Sirolimus blocks this pathway. The safety and efficacy of sirolimus treatment of LAM were investigated in clinical trials that compared sirolimus treatment...
69 KB (6,838 words) - 09:56, 30 July 2024
Lymphangioma (section Sirolimus)
lymphatics feeding into the lymphocele." Sirolimus is used to treat lymphangioma. Treatment with sirolimus can decrease pain and the fullness of venous...
22 KB (2,577 words) - 02:31, 9 September 2024
Immunosuppressive drug (section Sirolimus)
Everolimus is an analog of sirolimus and also is an mTOR inhibitor. Zotarolimus is a semi-synthetic derivative of sirolimus used in drug-eluting stents...
29 KB (3,378 words) - 13:22, 5 September 2024
MTOR inhibitors (section Sirolimus)
sites for mTOR and FKBP12. The bacterial natural product rapamycin or sirolimus, a cytostatic agent, has been used in combination therapy with corticosteroids...
57 KB (6,278 words) - 21:51, 24 August 2024
needed] It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR)...
27 KB (2,534 words) - 22:53, 12 July 2024
(mTORC1) led to successful use of rapamycin analog sirolimus in clinical trials and FDA approval of sirolimus for treatment of LAM. TSC1 and TSC2 form a tumor...
100 KB (11,094 words) - 23:14, 30 August 2024
medications (dapsone, sulfasalazine), immunosuppressants (cyclosporin, sirolimus) or other medications like omalizumab can be used. These options are explained...
50 KB (5,739 words) - 01:05, 5 September 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
57 KB (5,140 words) - 13:01, 20 August 2024
Sirolimus, a compound that inhibits mTOR signalling, is being studied to treat plexiform neurofibromas. The combination of erlotinib with sirolimus was...
30 KB (3,257 words) - 07:19, 4 August 2024
provide a "scaffold" to open the artery. An anti-rejection-type medication, sirolimus, helps to limit the overgrowth of normal cells while the artery heals...
2 KB (178 words) - 20:25, 12 March 2024
hypomagnesemia, hyperglycemia, diabetes mellitus, itching, lung damage (sirolimus also causes lung damage), and various neuropsychiatric problems such as...
43 KB (4,357 words) - 08:11, 15 July 2024
usually caused by the prolonged use of T cell suppressant drugs, such as sirolimus, tacrolimus, or ciclosporin. The Epstein-Barr virus, which infects >90%...
8 KB (776 words) - 14:33, 15 August 2024
and Drug Administration (FDA) were sirolimus-eluting stents (SES), which release a natural product called sirolimus, an immunosuppressant drug. SES were...
136 KB (14,025 words) - 17:02, 29 August 2024
cyclophosphamide, ciclosporin, tacrolimus, everolimus, thymoglobulin and sirolimus. Newer, so-called "biologic drugs" or monoclonal antibodies, are also...
25 KB (2,838 words) - 05:46, 13 August 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
23 KB (2,058 words) - 11:30, 1 July 2024
drug-eluting stents to be utilized were the paclitaxel-eluting stent and the sirolimus-eluting stent, both of which have received approval from the U.S. Food...
48 KB (5,361 words) - 13:22, 15 June 2024
substances that have been studied for GvHD treatment include, for example: sirolimus, pentostatin, etanercept, and alemtuzumab. In August 2017, the US FDA...
39 KB (4,445 words) - 07:04, 7 September 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
174 KB (16,058 words) - 01:45, 11 September 2024
after, in particular, high-dose therapy. Immunosuppressive drugs, such as sirolimus, mycophenolate mofetil, tacrolimus, ciclosporin, leflunomide and TNF inhibitors...
9 KB (828 words) - 17:16, 9 May 2024
disopyramide, Immunosuppressants such as tacrolimus, voclosporin and sirolimus, neuroleptics like clozapine, lurasidone and pimozide, as well as some...
42 KB (3,598 words) - 14:41, 6 August 2024
hypogammaglobulinemia (transient) requiring IVIgG replacement.[citation needed] Sirolimus (rapamycin, rapamune) which is a mTOR (mammalian target of rapamycin)...
26 KB (2,502 words) - 02:54, 15 July 2024
cyclophosphamide, mycophenolate, intravenous immunoglobulin, rituximab, sirolimus, alefacept, and the tyrosine kinase inhibitors, imatinib, nilotinib, and...
38 KB (3,293 words) - 18:29, 29 August 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
25 KB (2,350 words) - 19:31, 1 July 2024
coronary stent that combines Genous with an antiproliferative, biodegradable sirolimus drug elution. The Combo Stent was shown to be as effective as a paclitaxel-eluting...
3 KB (252 words) - 13:07, 15 September 2021
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
47 KB (4,718 words) - 01:43, 5 September 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
135 KB (14,086 words) - 21:47, 9 September 2024
2018). "Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre...
12 KB (923 words) - 06:22, 2 September 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
42 KB (3,900 words) - 01:11, 28 August 2024
triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
9 KB (706 words) - 02:50, 8 July 2024
ratio remained unchanged. Quetiapine (Seroquel) Repaglinide (Prandin) Sirolimus (Rapamycin, Rapamune) Tamoxifen (Nolvadex): Tamoxifen is metabolized by...
55 KB (5,720 words) - 16:53, 17 August 2024