Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. In addition, tetherin...
20 KB (2,458 words) - 23:57, 29 August 2023
Host switch (section Tetherin countermeasures)
acid is unknown. Tetherin is a defence protein in the innate immune response whose production is activation by interferon. Tetherin specifically inhibits...
31 KB (3,863 words) - 12:36, 25 January 2024
tetherin) and requires Vpu’s TM domain. however, the exact mechanism of how Vpu counteracts BST-2 is still unclear. In the absence of Vpu, tetherin binds...
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2011). "Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu". Journal of Virology...
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CD9 and CD81 CD316 IGSF8, (Immunoglobulin superfamily member 8) CD317 Tetherin or BST2 (bone marrow stromal antigen 2), is a lipid raft associated protein...
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defense against retroviruses, along with the APOBEC family of proteins, tetherin and TRIM22. TRIM5α belongs to the TRIM protein family (TRIM stands for...
16 KB (2,024 words) - 17:30, 25 March 2024
respect to retroviruses, relevant genes include TRIM5alpha, APOBEC, and Tetherin, representing directly antiviral effects Primes alveolar macrophages against...
56 KB (6,477 words) - 22:51, 28 May 2024
"Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin". Journal of Virology. 83, 4 (4): 1837–44. doi:10.1128/JVI.02211-08. PMC 2643743...
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host-specific factors that restrict replication of HIV-1 in macaques. Tetherin, a potent antiviral factor, was also discovered in his lab and shown to...
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cellular mechanisms through which Vpu counteracts BST2 (also designated Tetherin), an interferon-regulated host factor that strongly inhibits the release...
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viroporin Vpu promotes viral budding through interactions with CD4 and tetherin, though the precise molecular mechanism of this interaction is not known...
20 KB (1,967 words) - 00:33, 29 November 2023
(2014). "Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation". Journal...
10 KB (974 words) - 10:10, 20 May 2024