• Thumbnail for Tetherin
    Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. In addition, tetherin...
    20 KB (2,458 words) - 23:57, 29 August 2023
  • Thumbnail for Host switch
    acid is unknown. Tetherin is a defence protein in the innate immune response whose production is activation by interferon. Tetherin specifically inhibits...
    31 KB (3,863 words) - 12:36, 25 January 2024
  • Thumbnail for Vpu protein
    tetherin) and requires Vpu’s TM domain. however, the exact mechanism of how Vpu counteracts BST-2 is still unclear. In the absence of Vpu, tetherin binds...
    11 KB (1,419 words) - 04:26, 15 April 2024
  • Thumbnail for Ubiquitin
    2011). "Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu". Journal of Virology...
    98 KB (11,068 words) - 18:25, 16 July 2024
  • CD9 and CD81 CD316 IGSF8, (Immunoglobulin superfamily member 8) CD317 Tetherin or BST2 (bone marrow stromal antigen 2), is a lipid raft associated protein...
    96 KB (467 words) - 06:58, 14 October 2022
  • Thumbnail for TRIM5alpha
    defense against retroviruses, along with the APOBEC family of proteins, tetherin and TRIM22. TRIM5α belongs to the TRIM protein family (TRIM stands for...
    16 KB (2,024 words) - 17:30, 25 March 2024
  • Thumbnail for Interferon gamma
    respect to retroviruses, relevant genes include TRIM5alpha, APOBEC, and Tetherin, representing directly antiviral effects Primes alveolar macrophages against...
    56 KB (6,477 words) - 22:51, 28 May 2024
  • Thumbnail for AmfAR
    "Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin". Journal of Virology. 83, 4 (4): 1837–44. doi:10.1128/JVI.02211-08. PMC 2643743...
    62 KB (6,911 words) - 16:58, 9 June 2024
  • host-specific factors that restrict replication of HIV-1 in macaques. Tetherin, a potent antiviral factor, was also discovered in his lab and shown to...
    10 KB (989 words) - 02:39, 23 May 2024
  • cellular mechanisms through which Vpu counteracts BST2 (also designated Tetherin), an interferon-regulated host factor that strongly inhibits the release...
    18 KB (1,491 words) - 23:27, 23 July 2024
  • Thumbnail for Viroporin
    viroporin Vpu promotes viral budding through interactions with CD4 and tetherin, though the precise molecular mechanism of this interaction is not known...
    20 KB (1,967 words) - 00:33, 29 November 2023
  • (2014). "Feline immunodeficiency virus envelope glycoproteins antagonize tetherin through a distinctive mechanism that requires virion incorporation". Journal...
    10 KB (974 words) - 10:10, 20 May 2024