• Thumbnail for Persistent carbene
    nitrogen atoms in triazol-5-ylidene, there are two possible isomers, namely 1,2,3-triazol-5-ylidenes and 1,2,4-triazol-5-ylidenes. The triazol-5-ylidenes based...
    62 KB (6,933 words) - 11:59, 13 August 2024
  • Thumbnail for 3-Amino-1,2,4-triazole
    3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent. 3-AT is a competitive...
    7 KB (498 words) - 04:11, 26 May 2024
  • Thumbnail for Trazodone
    Trazodone (category 2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1,2,4-triazol-3-ones)
    21% Identifiers IUPAC name 2-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one CAS Number 19794-93-5 Y PubChem CID 5533...
    105 KB (9,933 words) - 15:41, 7 September 2024
  • Thumbnail for Anastrozole
    nonsteroidal benzyl triazole. It is also known as α,α,α',α'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile. Anastrozole is structurally related...
    27 KB (2,332 words) - 04:27, 27 February 2024
  • The triazol-5-ylidenes are a group of persistent carbenes which includes the 1,2,4-triazol-5-ylidene system and the 1,2,3-triazol-5-ylidene system. As...
    22 KB (2,758 words) - 23:40, 9 December 2023
  • Thumbnail for Deferasirox
    4-hydrazinobenzoic acid in the presence of base to give 4-(3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl)benzoic acid (deferasirox). Deferasirox ranked second on the list...
    11 KB (783 words) - 04:50, 7 September 2024
  • Thumbnail for Efinaconazole
    (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol CAS Number 164650-44-6 PubChem CID 489181 DrugBank DB09040...
    10 KB (715 words) - 01:12, 2 September 2024
  • Thumbnail for Nitrotriazolone
    Semicarbazide hydrochloride is condensed with formic acid to produce 1,2,4-triazol-3-one, which is nitrated with nitric acid to form nitrotriazolone. In...
    7 KB (445 words) - 11:35, 6 September 2023
  • Thumbnail for Cerium nitrates
    103°41'. dithallium diaquapentanitratocerate dihydrate. Bis{4-[(4H-1,2,4-triazol-4-yl)iminomethyl]pyridinium} diaquapentanitratocerate. (C8H8N5)2[Ce(NO3)5(H2O)2]...
    25 KB (2,646 words) - 11:06, 3 January 2024
  • Thumbnail for Letrozole
    half-life 2 days Excretion Kidney Identifiers IUPAC name 4,4'-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile CAS Number 112809-51-5 Y PubChem CID 3902...
    20 KB (1,820 words) - 06:05, 2 June 2024
  • Thumbnail for 2,4-Dinitrophenol
    explosive formulation constituents: 2,4-Dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine". Journal of Hazardous Materials. 280:...
    35 KB (3,728 words) - 18:23, 1 August 2024
  • Thumbnail for Fluconazole
    Kidney 61–88% Identifiers IUPAC name 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol CAS Number 86386-73-4 Y PubChem CID 3365 DrugBank DB00196 Y...
    31 KB (2,821 words) - 10:58, 27 May 2024
  • Thumbnail for Aprepitant
    5-bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a potent, orally active, long-acting morpholine...
    23 KB (2,210 words) - 20:52, 4 September 2024
  • Thumbnail for TPA-023
    (November 2005). "7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally selective...
    7 KB (638 words) - 14:12, 5 September 2024
  • Thumbnail for Tebuconazole
    1-(4-Chlorophenyl)- 4,4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan- 3-ol Other names (±)-1-(4-Chlorophenyl)-4,4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan-3-ol...
    4 KB (198 words) - 17:45, 7 September 2024
  • Thumbnail for MRK-016
    3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective...
    3 KB (166 words) - 22:20, 3 December 2023
  • Thumbnail for Maraviroc
    4,4-Difluoro-N-[(1S)-3-{(1R,3s,5S)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-phenylpropyl] cyclohexanecarboxamide...
    12 KB (954 words) - 13:32, 23 April 2024
  • Thumbnail for Rizatriptan
    Excretion 82% urine; 12% feces Identifiers IUPAC name N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine CAS Number 145202-66-0 Y PubChem...
    11 KB (669 words) - 03:31, 8 September 2024
  • Thumbnail for Isavuconazonium
    (methylamino)acetyl]oxy}methyl)pyridin-2-yl]carbamoyl}oxy)ethyl]-1H-1,2,4-triazol-4-ium CAS Number 742049-41-8 sulfate: 946075-13-4 Y PubChem CID 6918606...
    25 KB (1,437 words) - 21:56, 19 August 2024
  • Thumbnail for Paclobutrazol
    is brominated and the resulting compound treated with the sodium salt of 1,2,4-triazole in a nucleophilic substitution reaction. The final reduction reaction...
    23 KB (2,246 words) - 19:27, 9 August 2024
  • Thumbnail for Posaconazole
    Posaconazole (category 1,2,4-Triazol-3-ones)
    1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2- hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one...
    14 KB (827 words) - 12:14, 7 September 2024
  • Thumbnail for Terconazole
    (4-isopropyl-1-piperazinyl)phenoxy]methyl}-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole. Terconazole has a melting point of 126.3 °C (259.34 °F). The molecular...
    17 KB (1,964 words) - 00:17, 9 March 2024
  • Thumbnail for Itraconazole
    Itraconazole (category 1,2,4-Triazol-3-ones)
    4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-Δ2-1,2,4-triazolin-5-one CAS Number 84625-61-6 Y...
    26 KB (2,397 words) - 16:07, 20 May 2024
  • Thumbnail for Fosaprepitant
    ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid CAS Number 172673-20-0 Y 265121-04-8 (dimeglumine)...
    6 KB (248 words) - 21:04, 4 September 2024
  • Thumbnail for Hexaconazole
    Hexaconazole Names Systematic IUPAC name 2-(2,4-Dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)hexan-2-ol Identifiers CAS Number 79983-71-4 Y 3D model (JSmol)...
    3 KB (78 words) - 14:55, 21 May 2024
  • Thumbnail for Talazoparib
    Identifiers IUPAC name (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one CAS Number...
    16 KB (1,230 words) - 04:49, 15 September 2024
  • Thumbnail for List of benzodiazepines
    4]diazepin-2(3H)-one 21738192 Compound 6a 9.5 † 7-chloro-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one JC-184 7-bromo-5-(2-thienyl)-1H-benzo[e]...
    108 KB (3,088 words) - 07:42, 22 July 2024
  • Thumbnail for MRK-409
    humans at doses above 1 mg. "1,2,4-Triazolo(4,3-b)pyridazine, 7-cyclobutyl-3-(2,6-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-". "MRK-409"...
    4 KB (319 words) - 15:54, 30 March 2024
  • Thumbnail for Deucravacitinib
    Identifiers IUPAC name 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)phenyl)amino)-N-(trideuteromethyl)pyridazine-3-carboxamide CAS...
    12 KB (697 words) - 09:25, 1 July 2024
  • Thumbnail for Doravirine
    Identifiers IUPAC name 3-Chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinyl}oxy)benzonitrile...
    4 KB (199 words) - 08:43, 10 July 2024