• Thumbnail for Antithrombin
    (thrombin) and factor Xa. Antithrombin is also termed antithrombin III (AT III). The designations antithrombin I through to antithrombin IV originate in early...
    46 KB (5,418 words) - 12:45, 29 August 2024
  • Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III. This deficiency may be inherited or acquired. It is a rare...
    5 KB (474 words) - 23:41, 27 November 2023
  • Thumbnail for Fresh frozen plasma
    rechecking laboratory values. Use in antithrombin III deficiency: FFP can be used as a source of antithrombin III in patients who are deficient of this...
    17 KB (1,769 words) - 09:45, 14 January 2024
  • Thumbnail for Coagulation
    Factor V or high levels of FVIII, also may lead to a thrombotic tendency. Antithrombin is a serine protease inhibitor (serpin) that degrades the serine proteases:...
    64 KB (6,553 words) - 13:35, 26 September 2024
  • Thumbnail for Anticoagulant
    pig intestines and bovine lungs. UFH binds to the enzyme inhibitor antithrombin III (AT), causing a conformational change that results in its activation...
    78 KB (8,755 words) - 15:35, 24 September 2024
  • Thumbnail for CSL Limited
    (Rh(D) immunoglobulin G) Tetanus Immunoglobulin-VF Thrombotrol-VF (antithrombin III) Vivaglobin, sub-cutaneous human immune globulin indicated for the...
    31 KB (2,916 words) - 01:35, 15 August 2024
  • hydrogen bonding. Some examples of heparin binding proteins include antithrombin III. It is thought that much protein interaction with heparin is not direct...
    7 KB (884 words) - 16:14, 24 October 2023
  • compete for similar sites on factor Va. Factor Xa is inhibited by the antithrombin III/heparin system, which also acts to inhibit thrombin. Deficiencies of...
    25 KB (3,112 words) - 19:03, 28 February 2024
  • Thumbnail for Nephrotic syndrome
    particularly those caused by a decrease in blood antithrombin III levels due to leakage. Antithrombin III counteracts the action of thrombin. Thrombosis...
    57 KB (6,360 words) - 06:38, 6 October 2024
  • Thumbnail for Fondaparinux
    direct factor Xa inhibitors, it mediates its effects indirectly through antithrombin III, but unlike heparin, it is selective for factor Xa. Fondaparinux is...
    9 KB (711 words) - 10:19, 16 August 2023
  • Thumbnail for Glycocalyx
    Extracellular superoxide dismutase (SOD3) Angiotensin converting enzyme Antithrombin-III Lipoprotein lipase Apolipoproteins Growth factors Chemokines The enzymes...
    19 KB (2,192 words) - 08:58, 29 July 2024
  • Thumbnail for Warfarin necrosis
    S deficiency, activated protein C resistance (Factor V Leiden) and antithrombin III deficiency. Although the above hypothesis is the most commonly accepted...
    11 KB (1,332 words) - 18:31, 11 March 2023
  • Thumbnail for Serpin
    ovalbumin, to give what was initially called the alpha1-antitrypsin-antithrombin III-ovalbumin superfamily of serine proteinase inhibitors, but was subsequently...
    137 KB (14,301 words) - 15:34, 20 September 2024
  • Thumbnail for Thrombocythemia
    By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin...
    11 KB (1,066 words) - 01:55, 17 March 2024
  • Thumbnail for Protein S
    Defekte von Antithrombin III, Protein C und Protein S" [Molecular biological basis and diagnosis of hereditary defect of antithrombin III, protein c and...
    14 KB (1,777 words) - 17:34, 10 April 2024
  • Thumbnail for Heparan sulfate
    divided into two functional subcategories, those that generate an antithrombin III binding site (HS3ST1 and HS3ST5) and those that generate a herpes simplex...
    36 KB (4,151 words) - 06:37, 27 May 2024
  • Thumbnail for Thrombus
    cascade. Heparin works by binding to and activating the enzyme inhibitor antithrombin III, an enzyme that acts by inactivating thrombin and factor Xa. In contrast...
    21 KB (2,279 words) - 02:02, 18 September 2024
  • proteins Coagulation: increase circulating level of factors 2, 7, 9, 10, antithrombin III, plasminogen increase platelet adhesiveness Fluid balance: salt (sodium)...
    27 KB (343 words) - 01:20, 8 October 2024
  • Thumbnail for Pulmonary heart disease
    screen- to detect chronic venous thromboembolism (proteins C and S, antithrombin III, homocysteine levels) The diagnosis of pulmonary heart disease is not...
    14 KB (1,323 words) - 04:52, 10 April 2024
  • Thumbnail for Cardiopulmonary bypass
    requiring CPB. A small percentage of patients, such as those with an antithrombin III deficiency, may exhibit resistance to heparin. In these patients, patients...
    34 KB (4,038 words) - 03:34, 8 October 2024
  • lead to mutations through intrastrand and interstrand switching. The antithrombin III gene's coding region is an example of an imperfect inverted repeat...
    31 KB (3,451 words) - 20:17, 11 September 2024
  • Thumbnail for Budd–Chiari syndrome
    mutation (3%), protein C deficiency (5%), protein S deficiency (4%), and antithrombin III deficiency(1%). Budd–Chiari syndrome may be the presenting sign of...
    22 KB (2,301 words) - 17:55, 30 September 2024
  • Thumbnail for Dalteparin sodium
    stroke or heart attack. Dalteparin acts by potentiating the activity of antithrombin III, inhibiting formation of both Factor Xa and thrombin. It is normally...
    6 KB (483 words) - 19:31, 5 January 2024
  • transaminase ASX asymptomatic A-T ataxia-telangiectasia AT antithrombin angiotensin AT-III antithrombin III ATA antitransglutaminase antibodies ATB antibiotic...
    19 KB (13 words) - 21:38, 27 August 2024
  • Thumbnail for Dermatan sulfate
    moving fraction with a low molecular weight of 7000 Da and affinity for antithrombin III) and 20% dermatan sulfate with a high molecular weight (25,000 Da)...
    4 KB (334 words) - 07:07, 2 September 2023
  • thrombin. Unlike thrombin, reptilase is resistant to inhibition by antithrombin III. Thus, the reptilase time is not prolonged in blood samples containing...
    2 KB (189 words) - 06:33, 14 December 2023
  • Thumbnail for Bivalirudin
    thrombosis-thrombocytopenia syndrome. It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin...
    28 KB (2,792 words) - 20:16, 23 April 2024
  • 100 x 109 L-1) or by testing the levels of fibrin metabolites and antithrombin III.[citation needed] Elevated serum levels of certain proteins, in particular...
    33 KB (3,744 words) - 07:18, 5 September 2024
  • Thumbnail for Virchow's triad
    Leiden mutation, coagulation factor II G2021A mutation, deficiency of antithrombin III, protein C or S deficiency, nephrotic syndrome, changes after severe...
    10 KB (707 words) - 23:21, 30 August 2024
  • Thumbnail for Thrombophilia
    severe in their propensity to cause thrombosis. The main ones are antithrombin III deficiency, protein C deficiency and protein S deficiency. Milder rare...
    47 KB (5,585 words) - 01:20, 24 September 2024