• Thumbnail for Vitamin B12
    Vitamin B12 (redirect from Cobalamin)
    Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which...
    112 KB (12,246 words) - 22:03, 13 August 2024
  • Thumbnail for Cobalamin biosynthesis
    Cobalamin biosynthesis is the process by which bacteria and archea make cobalamin, vitamin B12. Many steps are involved in converting aminolevulinic acid...
    36 KB (3,654 words) - 06:20, 10 June 2024
  • Thumbnail for Methylcobalamin
    Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano group at the cobalt...
    10 KB (836 words) - 22:47, 23 January 2024
  • Thumbnail for Cyanocobalamin
    stable cobalamin analogs. The products are usually extracted and purified by phenol-methylene chloride extraction or by column chromatography. Cobalamin analogs...
    30 KB (2,655 words) - 03:29, 5 August 2024
  • Thumbnail for Vitamin B12 deficiency
    Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin...
    118 KB (13,134 words) - 19:21, 1 August 2024
  • Thumbnail for Cobalamin riboswitch
    Cobalamin riboswitch is a cis-regulatory element which is widely distributed in 5' untranslated regions of vitamin B12 (Cobalamin) related genes in bacteria...
    22 KB (2,354 words) - 23:55, 30 June 2024
  • Thumbnail for Intrinsic factor
    Intrinsic factor (IF), cobalamin binding intrinsic factor, also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells...
    13 KB (1,453 words) - 04:02, 10 March 2024
  • Thumbnail for Methionine synthase
    the cobalamin-independent form, while algae have either one of the two, depending on species. Many different microorganisms express both the cobalamin-dependent...
    30 KB (3,437 words) - 07:25, 16 May 2024
  • Thumbnail for Hydroxocobalamin
    B12 and a member of the cobalamin family of compounds. It is found in both raw and cooked beef, together with other cobalamins. Hydroxocobalamin, or another...
    21 KB (2,021 words) - 18:44, 15 July 2024
  • methyl group to Hcy to form Met. Methionine Syntheses can be cobalamin-dependent and cobalamin-independent: Plants have both, animals depend on the...
    28 KB (3,051 words) - 10:03, 4 June 2024
  • Transcobalamins are carrier proteins which bind cobalamin (B12). Transcobalamin I (TC-1), also known as haptocorrin (HC), R-factor, and R-protein is encoded...
    3 KB (330 words) - 06:11, 5 May 2024
  • Adenosylcobinamide-GDP ribazoletransferase (EC 2.7.8.26, CobS, cobalamin synthase, cobalamin-5'-phosphate synthase, cobalamin (5'-phosphate) synthase) is an enzyme with systematic...
    2 KB (238 words) - 19:48, 4 April 2024
  • Thumbnail for Homocystinuria
    of which is CBS deficiency. Others include the re-methylation defects (cobalamin defects, methionine synthase deficiency, MTHFR) and vitamin deficiencies...
    13 KB (1,361 words) - 20:21, 16 August 2024
  • Thumbnail for Cob(I)yrinic acid a,c-diamide adenosyltransferase
    adenosyltransferase) EC 2.5.1.17 is an enzyme which catalyses the conversion of cobalamin (vitamin B12) into one of its coenzyme forms, adenosylcobalamin (coenzyme...
    7 KB (631 words) - 13:35, 26 August 2023
  • Molloy, Anne M. (2014). "Guidelines for the diagnosis and treatment of cobalamin and folate disorders". British Journal of Haematology. 166 (4): 496–513...
    8 KB (794 words) - 02:22, 3 December 2023
  • Thumbnail for Shar Pei
    Suchodolski, Jan S.; Steiner, Jörg M. (1 March 2010). "Association Study of Cobalamin Deficiency in the Chinese Shar Pei". Journal of Heredity. 101 (2): 211–217...
    19 KB (2,106 words) - 16:20, 8 August 2024
  • Thumbnail for Megaloblastic anemia
    is not elevated in folic acid deficiency. Direct measurement of blood cobalamin remains the gold standard because the test for elevated methylmalonic...
    13 KB (1,255 words) - 19:34, 7 August 2024
  • Particularly of note is the cobalt complex, cobalamin (Vitamin B12) commonly used as a dietary supplement. Cobalamin is an important complex used in the manufacture...
    42 KB (5,188 words) - 00:17, 27 June 2024
  • Thumbnail for Cobalt
    acid rain. Cobalt is the active center of a group of coenzymes called cobalamins. Vitamin B12, the best-known example of the type, is an essential vitamin...
    96 KB (10,294 words) - 12:45, 13 August 2024
  • Thumbnail for MMACHC
    similar to TonB, a bacterial protein involved in energy transduction for cobalamin uptake. The MMACHC gene product catalyzes the decyanation of cyanocobalamin...
    9 KB (1,111 words) - 22:27, 26 April 2024
  • Thumbnail for Macaw
    well as other herbivorous animals, use the clay licks as a source of cobalamin, otherwise known as vitamin B12. Macaws and their feathers have attracted...
    19 KB (2,017 words) - 11:34, 6 June 2024
  • Thumbnail for Haptocorrin
    Ferreira D, Yue WW, Froese DS (May 2023). "The complex machinery of human cobalamin metabolism". J Inherit Metab Dis. 46 (3): 406–20. doi:10.1002/jimd.12593...
    14 KB (1,810 words) - 04:17, 1 April 2024
  • Thumbnail for Pernicious anemia
    B12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. Vitamin B12 deficiency is also prevalent in patients having...
    56 KB (6,027 words) - 12:46, 25 April 2024
  • Pyridoxal-5-Phosphate Pyridoxamine Vitamin B7 (biotin) Vitamin B9 (folate) Vitamin B12 (cobalamin) Choline Vitamin A (e.g. retinol (see also - provitamin A carotenoids))...
    5 KB (381 words) - 04:59, 1 April 2024
  • generally used to measure the amount of cobalamin in food. Its growth rate is proportional to the amount of cobalamin in the growth medium. However, lactis...
    3 KB (330 words) - 06:09, 8 November 2023
  • Thumbnail for Nicotinate-nucleotide—dimethylbenzimidazole phosphoribosyltransferase
    intermediate for the lower ligand of cobalamin. It is one of the enzymes of the anaerobic pathway of cobalamin biosynthesis, and one of the four proteins...
    9 KB (928 words) - 17:58, 23 January 2024
  • catalyzing difficult biochemical reactions, especially folic acid and cobalamin (vitamin B12). Among other honors, she was elected to the National Academy...
    15 KB (1,328 words) - 04:30, 23 July 2024
  • Thumbnail for Hypersegmented neutrophil
    1996). "Neutrophil nuclear segmentation in mild cobalamin deficiency: relation to metabolic tests of cobalamin status and observations on ethnic differences...
    6 KB (487 words) - 08:14, 18 January 2024
  • Thumbnail for Methylmalonic acidemias
    disorder or clinical syndrome. Also known as vitamin B12, this form of cobalamin is a required cofactor of methylmalonyl-CoA mutase. Even with a functional...
    49 KB (4,433 words) - 18:08, 16 June 2024
  • Thumbnail for S-Adenosyl methionine
    one of the two classes of methionine synthases (i.e. cobalamin-dependent (EC 2.1.1.13) or cobalamin-independent (EC 2.1.1.14)). This methionine can then...
    23 KB (2,421 words) - 11:10, 25 June 2024