Epothilones are a class of potential cancer drugs. Like taxanes, they prevent cancer cells from dividing by interfering with tubulin, but in early trials...
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Utidelone (redirect from Epothilone D)
It was approved for use in China in 2021. Utidelone is a member of the epothilone class of natural products, which are metabolites produced by the soil-dwelling...
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synthesis of polyketide natural products and drugs such as Oseltamivir and Epothilone. Aldol reactions Kohlpainter, Christian; Schulte, Markus; Falbe, Jürgen;...
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denticulata, zaragozic acid A, a potent inhibitor of sterol synthesis, and epothilone A and B, which have been proven to be very effective anticancer drugs...
22 KB (2,511 words) - 09:57, 9 January 2025
semi-synthetic analog of epothilone B, a natural chemical compound produced by Sorangium cellulosum. The structural difference between Epothilone B and Ixabepilone...
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antigen (PSMA) and has also developed, with Bristol-Myers Squibb, an epothilone-folic acid conjugate (BMS-753493), described at a 2008 conference. In...
9 KB (663 words) - 19:58, 12 September 2024
Sagopilone is a fully synthetic macrolide of the epothilone family with the molecular formula C30H41NO6S. The mechanism of action is similar to taxanes...
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List of chemotherapeutic agents (section Epothilones)
Daunorubicin Decitabine Docetaxel Doxifluridine Doxorubicin Epirubicin Epothilone Erlotinib Etoposide Exatecan Fludarabine Fluorouracil Fotemustine Gefitinib...
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resulting in apoptosis. Epothilone A and epothilone B exhibit both antifungal and cytotoxic properties. These epothilones are competitive inhibitors...
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; Sorensen, E. J.; Danishefsky, S. J. (1996). "Total Synthesis of (−)-Epothilone A". Angew. Chem. Int. Ed. Engl. 35 (2324): 2801. doi:10.1002/anie.199628011...
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Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
42 KB (3,865 words) - 06:23, 16 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
176 KB (16,443 words) - 02:48, 23 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
9 KB (689 words) - 09:24, 18 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
44 KB (4,070 words) - 01:23, 12 February 2025
used for localized cancer, gemcitabine, vinorelbine, etoposide, and epothilones are sometimes effective. Those with bone metastases benefit from regular...
140 KB (15,850 words) - 04:24, 16 February 2025
benzothiazoles. In addition to vitamin B1, the thiazole ring is found in epothilone. Other important thiazole derivatives are benzothiazoles, for example...
12 KB (1,151 words) - 11:33, 2 October 2024
and legs. Chemotherapy drugs associated with CIPN include thalidomide, epothilones, vinca alkaloids, taxanes, proteasome inhibitors, and the platinum-based...
155 KB (17,490 words) - 23:35, 18 February 2025
Vinflunine§ Vinorelbine#) Block microtubule disassembly Taxanes (Cabazitaxel Docetaxel# Larotaxel Ortataxel† Paclitaxel# Tesetaxel) Epothilones (Ixabepilone)...
34 KB (3,131 words) - 13:10, 17 February 2025
Gramicidin Zwittermicin A Antibiotic precursors ACV-Tripeptide Cytostatics Epothilone Fabclavine Bleomycin Immunosuppressants Ciclosporin (Cyclosporine A) Siderophores...
16 KB (1,833 words) - 15:06, 20 December 2023
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
43 KB (4,357 words) - 16:37, 12 January 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
45 KB (4,051 words) - 02:37, 8 February 2025
epithelium – epitope – EPO906 – epoetin alfa – epoetin beta – epothilone – epothilone B – epothilone D – epratuzumab – Epstein-Barr virus – EPT – ER – ER+ –...
69 KB (5,119 words) - 11:20, 3 June 2024
than most alternatives. Chiral pool synthesis is used to build a part of epothilone (an alternative to paclitaxel) from readily available enantiopure (–)-pantolactone...
5 KB (515 words) - 11:57, 6 September 2023
Vinflunine§ Vinorelbine#) Block microtubule disassembly Taxanes (Cabazitaxel Docetaxel# Larotaxel Ortataxel† Paclitaxel# Tesetaxel) Epothilones (Ixabepilone)...
31 KB (2,815 words) - 06:31, 16 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
73 KB (6,477 words) - 10:53, 17 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
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"Preclinical Pharmacology and Structure-Activity Studies of Epothilones". In Mulzer JH (ed.). The Epothilones: An Outstanding Family of Anti-Tumor Agents: From...
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undergraduate group led by a Wellesley College professor found that rats given epothilone B, a drug that binds to microtubules, took over a minute longer to fall...
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derivatives, such as erythromycins, tetracyclines, avermectins, and antitumor epothilones. Eukaryotic cells feature the compartmentalized membrane-bound organelles...
71 KB (7,366 words) - 15:44, 14 February 2025
Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Febantel Felodipine Fenbendazole Fentanyl...
42 KB (3,900 words) - 06:17, 16 January 2025