Macrophages (/ˈmækroʊfeɪdʒ/; abbreviated Mφ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such...
92 KB (10,131 words) - 14:06, 1 July 2024
The terms "macrophage" and "microphage" are used in ecology to describe heterotrophs that consume food in two different ways. Both macrophages and microphages...
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Macrophage polarization is a process by which macrophages adopt different functional programs in response to the signals from their microenvironment....
26 KB (3,077 words) - 07:06, 18 October 2023
Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages,...
17 KB (1,672 words) - 11:59, 30 August 2023
Regulatory macrophages (Mregs) represent a subset of anti-inflammatory macrophages. In general, macrophages are a very dynamic and plastic cell type and...
18 KB (1,836 words) - 10:07, 7 November 2023
An alveolar macrophage, pulmonary macrophage, (or dust cell) is a type of macrophage, a professional phagocyte, found in the airways and at the level of...
33 KB (3,862 words) - 16:23, 12 June 2024
Macrophage activation syndrome is a severe, potentially life-threatening, complication of several chronic rheumatic diseases of childhood. It occurs most...
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Macrophage elastase (EC 3.4.24.65, metalloelastase, human macrophage metalloelastase (HME), MMP-12) is an enzyme. This enzyme catalyses the following chemical...
2 KB (200 words) - 14:49, 26 August 2023
Smoker's macrophages are alveolar macrophages whose characteristics, including appearance, cellularity, phenotypes, immune response, and other functions...
28 KB (2,982 words) - 03:59, 10 April 2024
Bone-marrow-derived macrophage (BMDM) refers to macrophage cells that are generated in a research laboratory from mammalian bone marrow cells. BMDMs can...
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known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other...
17 KB (2,101 words) - 11:11, 21 December 2023
alveolar macrophages, also known as pulmonary foam cells, are cells found in bronchoalveolar lavage (BAL) specimens that consist of macrophages containing...
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CFU-GM (redirect from Granulocyte-macrophage progenitor)
CFU-GM (Colony Forming Unit–Granulocyte–Macrophage), also known as granulocyte–macrophage progenitor (GMP), is a colony forming unit. It is derived from...
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Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1α...
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Adipose tissue macrophages (ATMs) comprise resident macrophages present in adipose tissue. Besides adipocytes, adipose tissue contains the stromal vascular...
22 KB (2,339 words) - 05:38, 22 April 2024
Dermal macrophages are macrophages in the skin that facilitate skin homeostasis by mediating wound repair, hair growth, and salt balance. Their functional...
20 KB (2,371 words) - 23:00, 5 January 2024
A macrophage-activating factor (MAF) is a lymphokine or other receptor based signal that primes macrophages towards cytotoxicity to tumors, cytokine secretion...
8 KB (888 words) - 10:57, 29 July 2024
Macrophage migration inhibitory factor (MIF), also known as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase...
23 KB (2,498 words) - 21:29, 27 March 2024
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation...
44 KB (4,593 words) - 17:52, 18 April 2024
A tingible body macrophage (TBM) is a type of macrophage predominantly found in germinal centers of lymph nodes. They contain many phagocytized, apoptotic...
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Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role...
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Kupffer cell (redirect from Stellate macrophage)
Kupffer cells, also known as stellate macrophages and Kupffer–Browicz cells, are specialized cells localized in the liver within the lumen of the liver...
15 KB (1,861 words) - 05:25, 31 October 2023
Siderophage (redirect from Hemosiderin-laden macrophage)
A siderophage is a hemosiderin-containing macrophage. Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart...
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Tumor-associated macrophages (TAMs) are a class of immune cells present in high numbers in the microenvironment of solid tumors. They are heavily involved...
22 KB (2,507 words) - 23:16, 25 July 2024
particular mutation or signal. Excessive activation of neutrophils, monocytes/macrophages and dendritic cells leads to auto-inflammatory symptoms, while T cell...
18 KB (2,089 words) - 15:34, 21 August 2024
Epithelioid cell (redirect from Epithelioid macrophage)
cells (also called epithelioid histiocytes) are derivatives of activated macrophages resembling epithelial cells. Structurally, epithelioid cells (when examined...
19 KB (2,118 words) - 07:53, 6 August 2024
granulocyte-macrophage colony-stimulating factor receptor, also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte-macrophage colony-stimulating...
22 KB (2,709 words) - 04:21, 13 August 2024
g., monocytic phagocytes, osteoclasts), by circulating macrophages, and by tissue macrophages (e.g., Kupffer cells, microglia). Human CD68 is a Type I...
12 KB (1,369 words) - 13:37, 10 May 2024
Foam cell (redirect from Foamy macrophage)
Foam cells, also called lipid-laden macrophages, are a type of cell that contain cholesterol. These can form a plaque that can lead to atherosclerosis...
17 KB (2,058 words) - 16:39, 19 August 2024
Phagocyte (section Macrophages)
discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution...
74 KB (8,280 words) - 14:50, 17 August 2024