Nilotinib, sold under the brand name Tasigna marketed worldwide by Novartis, is a medication used to treat chronic myelogenous leukemia (CML) which has...
21 KB (1,811 words) - 18:02, 16 August 2024
these changes resulted in the discovery of nilotinib. Nilotinib is a selective Bcr-Abl kinase inhibitor. Nilotinib is 10-30 fold more potent than imatinib...
56 KB (6,473 words) - 03:56, 5 July 2024
of imatinib. A second TK inhibitor, nilotinib, was approved by the FDA for the same indication. In 2010, nilotinib and dasatinib were also approved for...
34 KB (3,877 words) - 01:25, 22 July 2024
journal). ALL and CML therapies have targeted JAK2 as well as BCR-ABL using nilotinib and ruxolitinib within murine models to downregulate downstream cytokine...
29 KB (3,538 words) - 15:01, 5 December 2023
currently available inhibitors to treat CML are imatinib, dasatinib, nilotinib, bosutinib and ponatinib. Gastrointestinal stromal tumors (GIST) are known...
43 KB (5,251 words) - 10:44, 24 June 2024
This is a list of adverse effects of the anti-cancer drug nilotinib, sorted by frequency of occurrence. Very common (>10% incidence) adverse effects include:...
5 KB (463 words) - 16:57, 20 March 2022
sirolimus, alefacept, and the tyrosine kinase inhibitors, imatinib, nilotinib, and dasatinib. Experimental therapies under investigation include endothelin...
38 KB (3,291 words) - 01:18, 9 May 2024
Sorafenib (Nexavar) Sunitinib (Sutent) Dasatinib (Sprycel) Lapatinib (Tykerb) Nilotinib (Tasigna) Bosutinib (Bosulif) Ponatinib (Iclusig) Asciminib (Scemblix)...
20 KB (2,234 words) - 01:21, 22 July 2024
Approval of Dasatinib and Nilotinib for Resistant Leukemia MD Anderson researchers demonstrate the efficacy of dasatinib and nilotinib, leading to FDA approval...
55 KB (5,332 words) - 18:57, 17 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
31 KB (3,430 words) - 11:40, 29 July 2024
distinguishes dasatinib from other CML treatments, such as imatinib and nilotinib. Although dasatinib only has a plasma half-life of three to five hours...
22 KB (1,994 words) - 04:41, 3 January 2024
Stalevo (carbidopa/levodopa/entacapone) Parkinson's disease Tasigna (nilotinib) Chronic myelogenous leukemia (first-line treatment) 998 2012 39% NICE...
144 KB (12,089 words) - 12:58, 16 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
68 KB (5,999 words) - 22:36, 15 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
149 KB (15,717 words) - 06:34, 13 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
92 KB (8,671 words) - 18:15, 17 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
24 KB (1,703 words) - 18:20, 18 August 2024
nikethamide (INN) Niktimvo Nilandron nileprost (INN) nilestriol (INN) nilotinib (USAN) nilprazole (INN) Nilstat niludipine (INN) nilutamide (INN) nilvadipine...
9 KB (417 words) - 07:03, 15 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
64 KB (7,427 words) - 21:08, 3 August 2024
ampicillin and amoxicillin; 2) anti-cancer medications, i.e., lorlatinib, nilotinib, imatinib (these three drugs are tyrosine kinase inhibitors that may also...
84 KB (8,872 words) - 03:05, 14 August 2024
Mitomycin L01DC04 Ixabepilone L01EA01 Imatinib L01EA02 Dasatinib L01EA03 Nilotinib L01EA04 Bosutinib L01EA05 Ponatinib L01EA06 Asciminib L01EB01 Gefitinib...
12 KB (877 words) - 15:36, 25 January 2024
Interferon-α Interleukin-2 Melphalan Methotrexate Mitoxantrone Nelarabine Nilotinib Oblimersen Pegaspargase Pentostatin Ponatinib Prednisone Rituximab Tretinoin...
1 KB (70 words) - 18:51, 14 November 2023
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
13 KB (1,177 words) - 00:03, 12 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
121 KB (13,799 words) - 20:57, 19 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
60 KB (6,879 words) - 14:26, 16 July 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
10 KB (579 words) - 06:46, 26 June 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
28 KB (2,570 words) - 16:18, 29 November 2023
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
26 KB (2,420 words) - 06:06, 17 August 2024
generation Bcr-Abl tyrosine-kinase inhibitor nilotinib (red) in complex with an Abl kinase domain (blue). Nilotinib is used to treat chronic myelogenous leukemia...
10 KB (1,179 words) - 18:31, 8 August 2024
mycophenolate, and tyrosine kinase inhibitors like erlotinib, dasatinib, and nilotinib. There is no clinically relevant drug interaction between rabeprazole...
67 KB (6,229 words) - 10:26, 19 August 2024
factor Kinase inhibitors: Agerafenib Axitinib Dasatinib Imatinib Masitinib Nilotinib Pazopanib Quizartinib Sorafenib Sunitinib Toceranib TGFβ See here instead...
10 KB (1,131 words) - 19:14, 31 March 2024