Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma)...
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In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant resulted in the...
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Phocomelia (redirect from Thalidomide syndrome)
appendage. A prominent cause of phocomelia is the mother's use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined...
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the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding...
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Cereblon E3 ligase modulator (redirect from Development of analogs of thalidomide)
immune responses) containing an imide group. The IMiD class includes thalidomide and its analogues (lenalidomide, pomalidomide, mezigdomide and iberdomide)...
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Teratology (section Thalidomide)
Chemical agents Prescription and recreational drugs (e.g., alcohol, thalidomide) Environmental toxins and contaminants (e.g., heavy metals such as mercury...
43 KB (4,756 words) - 17:35, 15 July 2024
considered a side effect. For information regarding birth defects, see thalidomide. Somnolence (drowsiness; ~40%) Edema (~60%) Hypotension (low blood pressure)...
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Josée Lake (section Thalidomide)
Canadian paralympic gold medallist swimmer, and thalidomide survivor. She was president of the Thalidomide Victims Association of Canada in 2019. Lake was...
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Stereochemistry (section Thalidomide example)
example of the importance of stereochemistry relates to the thalidomide disaster. Thalidomide is a pharmaceutical drug, first prepared in 1957 in Germany...
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1962) is an English thalidomide survivor and activist. She is a past chair of the National Advisory Committee of the Thalidomide Trust, the organisation...
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Wonder Drug (book) (redirect from Wonder Drug: The Secret History of Thalidomide in America and its Hidden Victims)
Wonder Drug: The Secret History of Thalidomide in America and Its Hidden Victims is a nonfiction book authored by Jennifer Vanderbes and published by...
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Grünenthal (section Thalidomide (Contergan))
the teratogenic drug thalidomide, marketed as the sleeping pill Contergan and promoted as a morning sickness preventive. Thalidomide caused severe birth...
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English rock musician, actor, writer and performance artist. He has thalidomide-induced phocomelia. Between 1980 and 1995 Fraser was a drummer with several...
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a British thalidomide survivor, painter, lace maker, and carriage driver with the RDA. Mercer was a representative of the global thalidomide community...
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Thalidomide!! A Musical is a British musical written and composed by Mat Fraser, who was born with phocomelia as a result of the drug thalidomide being...
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adjusted in people with kidney problems. Lenalidomide is closely related to thalidomide, which is known to cause severe birth defects, so its use during pregnancy...
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William McBride (doctor) (section Thalidomide case)
Australian obstetrician. He published a letter on the teratogenicity of thalidomide following the findings of a midwife named Pat Sparrow, which resulted...
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Enantioselective synthesis (section Thalidomide)
following the thalidomide disaster the development and licensing of drugs changed dramatically. First synthesized in 1953, thalidomide was widely prescribed...
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the other enantiomer is harmful, like salbutamol and thalidomide. The (R) enantiomer of thalidomide is effective against morning sickness, while the (S)...
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Heinrich Mückter (section Invention of thalidomide)
thalidomide was first made available on 1 October 1957, and it became the second best-selling medication in Germany after Bayer Aspirin. Thalidomide was...
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Helen B. Taussig (section Banning of thalidomide)
rather than by sound. Taussig is also known for her work in banning thalidomide and was widely recognized as a highly skilled physician. She was the...
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Terrence 'Terry' Wiles (born 12 January 1962) was one of the most disabled thalidomide babies born in the UK. He has since become known internationally through...
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compound of pomalidomide, thalidomide, was originally discovered to inhibit angiogenesis in 1994. Based upon this discovery, thalidomide was taken into clinical...
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gain support for the survivors of thalidomide. Her efforts resulted in life-time compensation for Canadian "thalidomiders", as well as a special fund for...
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deficiency), drugs (e.g. anticancer drugs, tetracyclines, many hormones, thalidomide), and environmental chemicals (e.g. mercury, lead, dioxins, PBDEs, HBCD...
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Chiral drugs (section Thalidomide)
wildly in their pharmacokinetic, pharmacodynamic profile. The tragedy of thalidomide illustrates the potential for extreme consequences resulting from the...
41 KB (4,547 words) - 13:45, 15 August 2024
activity of thalidomide in the chick and zebrafish was cast into doubt due to a 2013 report that pomalidomide (a more potent thalidomide analogue) does...
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antagonist. Racemization of pharmaceutical drugs can occur in vivo. Thalidomide as the (R) enantiomer is effective against morning sickness, while the...
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seek compensation for mothers who had taken the morning sickness drug thalidomide, which led to their children having severely deformed limbs. In 1984...
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1939) is a London art dealer and Thalidomide parent activist. He is the father of a daughter, Louise, disabled by thalidomide. Mason was educated at Highgate...
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