CD27 is a member of the tumor necrosis factor receptor superfamily. It is currently of interest to immunologists as a co-stimulatory immune checkpoint...
10 KB (1,133 words) - 07:09, 15 October 2024
that in humans is encoded by CD70 gene. CD70 is also known as a ligand for CD27. In physiological condition the expression of CD70 on immune cells is transient...
10 KB (1,089 words) - 07:18, 15 October 2024
superfamily—CD27, CD40, OX40, GITR and CD137. Another two stimulatory checkpoint molecules belong to the B7-CD28 superfamily—CD28 itself and ICOS. CD27: This...
31 KB (3,473 words) - 17:20, 19 November 2024
receptor. In humans, CD27 is a good marker for plasma cells; naïve B cells are CD27−, memory B-cells are CD27+ and plasma cells are CD27++. The surface antigen...
24 KB (2,793 words) - 18:41, 30 May 2024
promote the secretion of immunoglobulins though CD27/CD70 interactions. B cells begin expressing CD27 at the beginning of the centroblast stage and lose...
6 KB (638 words) - 20:33, 20 July 2024
Election Returns: District Definitions California Voter Foundation map - CD27 34°15′54″N 117°56′06″W / 34.26500°N 117.93500°W / 34.26500; -117.93500...
63 KB (644 words) - 01:42, 15 December 2024
distinguished by the cell surface marker CD27, although some subsets do not express CD27. Memory B cells that lack CD27 are generally associated with exhausted...
24 KB (3,168 words) - 14:40, 30 April 2024
umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70 in the Journal of Experimental Medicine. He is senior fellow in...
17 KB (1,622 words) - 01:02, 9 December 2024
CD226 or CRTAM) and TNF receptor super-family (TNFRSF) (such as 41-BB, OX40, CD27, GITR, HVEM, CD40, BAFFR, BAFF and others). Additionally, some co-stimulatory...
16 KB (1,951 words) - 06:29, 22 August 2024
receptors (BCR), high levels of IgM, Toll-like receptors (TLRs), CD21, CD1, CD9, CD27 with low to negligible levels of secreted-IgD, CD23, CD5, and CD11b that...
12 KB (1,506 words) - 10:52, 17 July 2024
domain, and includes several other non-cytokine ligands like receptors, CD40, CD27 and CD30, besides the ligands on which the family is named (TNF). Chemokine...
6 KB (442 words) - 05:35, 18 May 2024
immunotherapy for solid tumors and hematologic malignancies. It is an anti-CD27 antibody and helps activate T-cells. This drug was developed by Celldex Therapeutics...
3 KB (183 words) - 11:50, 27 December 2021
immature B cells. Memory B cells with increased CD27+/IgD—are less susceptible to immunosuppression. CD27-/IgD- memory B cells are associated with increased...
136 KB (14,834 words) - 21:34, 20 December 2024
supplied by CELTECH Sp. z o.o. in Poland. Scania 6×4 semi-truck Sweden Fuel semi-trucks CD27 Kayman 0 / 73 Supplied by CELTECH Sp. z o.o. in Poland....
197 KB (5,825 words) - 22:40, 21 December 2024
autoimmunity BAFF-R Low peripherial B-cell numbers, decreased antibody responses CD27 Hypogammaglobulinemia, absent memory B cells CD19 complex (CD19,CD81, CD21)...
35 KB (3,368 words) - 21:13, 24 September 2024
death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds...
8 KB (1,004 words) - 17:32, 4 January 2024
binding domain, and includes several other non-cytokine ligands like CD40, CD27 and CD30, besides the ligands on which the family is named. Seven transmembrane...
35 KB (3,951 words) - 06:50, 2 December 2024
expressing both naïve T cells markers, such as CD45RA+, CD45RO-, high levels of CD27, CD28, IL-7Rα (CD127), CD62L, and C-C chemokine receptor 7 (CCR7), as well...
17 KB (2,103 words) - 01:19, 11 November 2023
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
11 KB (1,335 words) - 22:36, 11 October 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
33 KB (3,930 words) - 21:04, 3 September 2024
genes: UNC13D, STX11, RAB27A, STXBP2, LYST, PRF1 1, SH2D1A, BIRC4, ITK, CD27, and MAGT1. Secondary HLH (sHLH) is associated with, and thought to be promoted...
29 KB (3,306 words) - 22:34, 12 November 2024
combination with other immunotherapy drugs blocking LAG3, B7-H3, KIR, OX40, PARP, CD27, and ICOS. Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was...
35 KB (3,450 words) - 03:38, 30 September 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
27 KB (3,103 words) - 10:19, 17 November 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
14 KB (1,446 words) - 16:23, 9 December 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
75 KB (9,574 words) - 10:20, 13 October 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
39 KB (4,995 words) - 22:41, 14 December 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
15 KB (1,878 words) - 00:38, 28 October 2024
bone marrow. Human B1 cells have been found to have marker profile of CD20+CD27+CD43+CD70- and could either be CD5+ or CD5-, which has been debated since...
11 KB (1,484 words) - 15:52, 8 May 2024
c d CD13 CD14 CD15 CD16 A B CD18 CD19 CD20 CD21 CD22 CD23 CD24 CD25 CD26 CD27 CD28 CD29 CD30 CD31 CD32 A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41...
25 KB (3,052 words) - 15:34, 14 September 2024
DuoBody-CD3xB7H4 (GEN1047) CD3, B7H4 Genmab Solid tumors II HexaBody-CD27 (GEN1053/BNT313) CD27 50:50 Genmab/BioNTech Solid tumors I GEN1056 (BNT322) Undisclosed...
26 KB (1,908 words) - 12:54, 15 December 2024