An enamine is an unsaturated compound derived by the condensation of an aldehyde or ketone with a secondary amine. Enamines are versatile intermediates...

The Stork enamine alkylation involves the addition of an enamine to a Michael acceptor (e.g., an α,β -unsaturated carbonyl compound) or another electrophilic...

pattern. Non-carbon nucleophiles such as water, alcohols, amines, and enamines can also react with an α,β-unsaturated carbonyl in a 1,4-addition. Some...

Shevchenko National University of Kyiv. He is also a scientific advisor of Enamine Ltd (Ukraine) and Lumobiotics GmbH (Germany). Source: Igor V. Komarov graduated...

reactions. In 1963, G. Stork reported the first enamine alkylation reaction for ketones - Stork enamine alkylation reaction. In 1976, Meyers reported the...

is widely used to convert ketones to enamines. Enamines derived from piperidine are substrates in the Stork enamine alkylation reaction. Upon treatment...

aldehydes toward nucleophilic addition by formation of enamines (e.g. used in the Stork enamine alkylation): International Union of Pure and Applied Chemistry...

titanium tetrachloride. In the Stork enamine alkylation, secondary amines form enamines when exposed to ketones. These enamines then react (possibly enantio­selectively)...

the modern field of asymmetric organocatalysis. Researches on asymmetric enamine catalysis applied to important intermediates in steroids synthesis is due...

from o-nitrotoluenes 1.[1][2][3] The first step is the formation of an enamine 2 using N,N-dimethylformamide dimethyl acetal and pyrrolidine.[4] The desired...

varying proportions. The active species is the hexafluoropropylamine; any enamine is converted into this by the hydrogen fluoride byproduct as the reaction...

[3+3]cycloaddition between a cyclic enone and an enamine catalyzed by n-butyllithium is a Stork enamine / 1,2-addition cascade reaction: Iron[pyridine(diimine)]...

bonded are far more common. Isothiazones are produced by oxidation of enamine-thiones. The ring structure of isothiazole is incorporated into larger...

of proline in the transition state determine the reaction outcome. An enamine is formed during the reaction and only one proline molecule is involved...

ammonia or a primary amine gives an imine With secondary amine gives an enamine With Grignard and organolithium reagents to give, after aqueous workup...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

reason, it forms a stable chloramine. It is commonly used to generate enamines. Morpholine is widely used in organic synthesis. For example, it is a building...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

and reduction by dihydroprecondylocarpine acetate synthase (DPAS), an enamine intermediate is formed. The intermediate undergoes fragmentation to produce...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

is a form of inverse-electron demand Diels-Alder reaction in which an enamine reacts with a 1,2,4-triazine to form the pyridine nucleus. The reaction...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

pairs include: ketone – enol: H−O−C=C ⇌ O=C−C−H, see keto–enol tautomerism enamine – imine: H−N−C=C ⇌ N=C−C−H cyanamide – carbodiimide guanidine – guanidine...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...

ketone) initially forms a phenylhydrazone which isomerizes to the respective enamine (or 'ene-hydrazine'). After protonation, a cyclic [3,3]-sigmatropic rearrangement...

electron delocalisation with the indole ring.[citation needed] LSD also has enamine-type reactivity because of the electron-donating effects of the indole...

subsequent hydrolysis of the remaining aluminium and iron. Acetals, imines, and enamines can be converted back into ketones by treatment with excess water under...

Nitrogen Amine Enamine Ammonium Hydrazo Nitrene Imine Oxime Hydrazone Azo Amide Imidate Amidine Carbamate Imide Nitrile Isonitrile Cyanate Isocyanate...