• Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • Thumbnail for SV40
    SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
    19 KB (2,245 words) - 11:19, 30 June 2024
  • Thumbnail for Three prime untranslated region
    Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The...
    20 KB (2,555 words) - 11:24, 22 February 2024
  • Thumbnail for CPEB
    CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine...
    19 KB (2,236 words) - 21:48, 18 August 2024
  • Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA...
    15 KB (1,894 words) - 16:46, 28 November 2023
  • Thumbnail for Post-transcriptional modification
    tail. The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA...
    11 KB (1,432 words) - 23:35, 24 July 2024
  • The cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements...
    9 KB (1,178 words) - 13:13, 22 February 2024
  • Thumbnail for Mature messenger RNA
    of a mature mRNA molecule occurs in 3 steps: Capping of the 5' end Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine...
    6 KB (596 words) - 00:20, 15 February 2023
  • Thumbnail for Primary transcript
    modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly...
    25 KB (3,184 words) - 12:37, 17 August 2024
  • Thumbnail for Messenger RNA
    early stop codon, which, upon translation, produces a shorter protein. Polyadenylation is the covalent linkage of a polyadenylyl moiety to a messenger RNA...
    49 KB (5,922 words) - 14:24, 18 August 2024
  • Thumbnail for U1A polyadenylation inhibition element (PIE)
    The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A...
    2 KB (175 words) - 17:50, 16 January 2022
  • Thumbnail for Gene
    Finally, the ends of gene transcripts are defined by cleavage and polyadenylation (CPA) sites, where newly produced pre-mRNA gets cleaved and a string...
    110 KB (12,568 words) - 07:41, 2 July 2024
  • Thumbnail for Long terminal repeat
    type 1 provirus, polyadenylation signals present in the 5' long terminal repeat (LTR) are disregarded while the identical polyadenylation signals present...
    11 KB (1,378 words) - 11:06, 3 December 2023
  • Thumbnail for Cell nucleus
    protein translation. The three main modifications are 5' capping, 3' polyadenylation, and RNA splicing. While in the nucleus, pre-mRNA is associated with...
    87 KB (9,882 words) - 23:43, 24 August 2024
  • Thumbnail for Gene expression
    decapping. Another modification is 3′ cleavage and polyadenylation. They occur if polyadenylation signal sequence (5′- AAUAAA-3′) is present in pre-mRNA...
    102 KB (11,438 words) - 16:50, 17 July 2024
  • Thumbnail for Alternative splicing
    viral proteins. In addition, the primary transcript contained multiple polyadenylation sites, giving different 3' ends for the processed mRNAs. In 1981, the...
    62 KB (7,809 words) - 17:56, 21 May 2024
  • Thumbnail for Macular degeneration
    ARMS2 gene though destabilization of its mRNA through deletion of the polyadenylation signal. ARMS2 protein may localize to the mitochondria and participate...
    90 KB (9,840 words) - 22:49, 25 August 2024
  • Thumbnail for GLD-2
    specific RNAs, forming a poly(A) tail, which is a process known as polyadenylation. For RNA specificity, GLD-2 associates with an RNA-binding protein...
    10 KB (1,396 words) - 10:08, 17 October 2022
  • major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation. Eukaryotic...
    39 KB (4,540 words) - 18:39, 20 July 2024
  • encodes one or more polyadenylation signals. Once the signals are transcribed into the mRNA, the proteins cleavage and polyadenylation specificity factor...
    13 KB (1,631 words) - 10:55, 5 June 2024
  • Thumbnail for Protein biosynthesis
    process of post-transcriptionally modifying pre-mRNA through capping, polyadenylation and splicing to produce a mature mRNA molecule ready for export from...
    40 KB (4,342 words) - 18:58, 2 April 2024
  • Immediacy, Expectancy: principles for treating combat stress reaction U1A polyadenylation inhibition element (PIE), an RNA element Collingwood Football Club...
    3 KB (420 words) - 20:18, 22 February 2024
  • Thumbnail for DNA virus
    terminates transcription upon reaching a specific signal, such as a polyadenylation site. dsDNA viruses make use of several mechanisms to replicate their...
    25 KB (2,893 words) - 04:22, 4 July 2023
  • Thumbnail for RNA polymerase
    template-independent addition of adenines at its new 3′ end, in a process called polyadenylation. Given that DNA and RNA polymerases both carry out template-dependent...
    41 KB (4,799 words) - 19:34, 17 April 2024
  • Thumbnail for RNA splicing
    related to Splicing. cDNA DBASS3/5 Exon junction complex mRNA capping Polyadenylation Post-transcriptional modification RNA editing SWAP protein domain,...
    37 KB (4,486 words) - 15:02, 23 July 2024
  • Thumbnail for BRCA1
    (September 1999). "Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50". Science. 285 (5433): 1576–9. doi:10.1126/science.285...
    121 KB (13,581 words) - 14:59, 8 August 2024
  • Thumbnail for Transcription (biology)
    template-independent addition of adenines at its new 3' end, in a process called polyadenylation. Beyond termination by a terminator sequences (which is a part of a...
    58 KB (6,787 words) - 20:17, 9 August 2024
  • behind another vehicle Surveillance, following someone's movements Polyadenylation, adding a poly(-A) tail to a nucleic acid Tail (disambiguation) This...
    471 bytes (98 words) - 00:11, 15 July 2021
  • Thumbnail for Facioscapulohumeral muscular dystrophy
    on the type of 4qA allele. A polyadenylation signal is within exon 3. Because exon 3 and its containing polyadenylation signal are not contained within...
    174 KB (16,320 words) - 05:33, 15 August 2024
  • Thumbnail for Directionality (molecular biology)
    3′-end of nascent messenger RNA is the site of post-transcriptional polyadenylation, which attaches a chain of 50 to 250 adenosine residues to produce...
    9 KB (1,191 words) - 13:38, 29 May 2024