Scrapie (/ˈskreɪpi/) is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform...

uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...

with overlapping signs and symptoms. TSEs in non-human mammals include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle – popularly...

protease-resistant form designated PrPRes such as the disease-causing PrPSc (scrapie) and an isoform located in mitochondria. The misfolded version PrPSc is...

either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The United Kingdom was afflicted with an outbreak...

astroglial hypertrophy in Scrapie, Kuru, Multiple Sclerosis and old age together with a note on the possible nature of the scrapie agent". Journal of Neurology...

the central nervous system in cattle. It is a fatal disease, similar to scrapie in sheep and goats, caused by a prion. A major epizootic affected the UK...

protein leading to a variety of spongiform encephalopathies such as kuru, scrapie and Creutzfeldt–Jakob disease. Ice VII, stable at room temperature but...

is a hypothetical infectious particle once theorized to be the cause of scrapie and other degenerative diseases of the central nervous system. It was thought...

to study and develop scrapie-resistant sheep. An infectious, persistent, and spontaneous disease, animals infected with scrapie must be quarantined and...

cow disease) in cattle, Creutzfeldt–Jakob disease (CJD) in humans, and scrapie in sheep. Natural infection causing CWD affects members of the deer family...

clinical trial that attempted to eliminate scrapie from sheep by breeding out susceptibility to it. Scrapie can kill up to twenty-five percent of sheep...

his 1998 PNAS review article on Prions, Prusiner wrote: "The idea that scrapie prions were composed of an amyloidogenic protein was truly heretical when...

hypersensitivity and inflammation. Hay mites are a suspected reservoir for scrapie, a prion disease of sheep. The mite Varroa destructor is a serious pest...

the possibility of transmission of scrapie, a deadly, degenerative prion disease of sheep and goats, though scrapie does not appear to be transmissible...

among the first to find evidence indicating that the infectious agent in Scrapie does not contain nucleic acid: a finding that was instrumental in understanding...

conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease...

In one-third of people with sporadic CJD, deposits of "prion protein (scrapie)", PrPSc, can be found in the skeletal muscle and/or the spleen. Diagnosis...

uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...

conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one population of animals, while others, like foot-and-mouth...

degenerative disease in humans. Kuru was shown to have remarkable similarity to scrapie, a disease of sheep and goats caused by an unconventional infectious agent...

have spontaneously developed the disease as well as sheep infected with scrapie, a similar disease in sheep, the inclusion of brain and spinal cord tissue...

although other reports have shown no significant effect, and treatment of scrapie in mice and sheep has also shown no effect. Possible reasons for the lack...

animals Bovine spongiform encephalopathy Camel spongiform encephalopathy Scrapie Chronic wasting disease Transmissible mink encephalopathy Feline spongiform...

mortality rate. Includes bovine spongiform encephalopathy (mad cow disease), scrapie, and kuru among others. Neonatal encephalopathy (hypoxic-ischemic encephalopathy):...

to, Bovine spongiform encephalopathy (BSE) "Mad cow disease" in cattle, scrapie in sheep and goats, and Creutzfeldt–Jakob disease (CJD) in humans. Bastian...

minutes. The 263K scrapie prion is inactivated relatively quickly by such sterilization procedures; however, other strains of scrapie, and strains of Creutzfeldt-Jakob...

Sclerotylosis SCOT deficiency Scott–Bryant–Graham syndrome Scott syndrome Scrapie Scurvy Scoliosis Scoliosis as part of NF Scoliosis with unilateral unsegmented...

Fibrils in brain of Rocky Mountain elk with chronic wasting disease contain scrapie amyloid. Guiroy DC, Williams ES, Song KJ, Yanagihara R, Gajdusek DC. Laboratory...

easily transmitted to pregnant women. Also of concern are the prion disease scrapie and the virus that causes foot-and-mouth disease (FMD), as both can devastate...