In biology, histones are highly basic proteins abundant in lysine and arginine residues that are found in eukaryotic cell nuclei and in most Archaeal phyla...
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Nucleosome (redirect from Histone post-translational modification)
eight proteins called histones, which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B...
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Epigenetics (section Histone modifications)
Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering...
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Histone H1 is one of the five main histone protein families which are components of chromatin in eukaryotic cells. Though highly conserved, it is nevertheless...
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Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl-CoA...
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both histone and non-histone proteins. HDACs allow histones to wrap the DNA more tightly. This is important because DNA is wrapped around histones, and...
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The histone code is a hypothesis that the transcription of genetic information encoded in DNA is in part regulated by chemical modifications (known as...
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Histone methylation is a process by which methyl groups are transferred to amino acids of histone proteins that make up nucleosomes, which the DNA double...
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Histone acetylation and deacetylation are the processes by which the lysine residues within the N-terminal tail protruding from the histone core of the...
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Histone variants are proteins that substitute for the core canonical histones (H3, H4, H2A, H2B) in nucleosomes in eukaryotes and often confer specific...
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variants of histone H3. These are denoted as Histone H3.1, Histone H3.2, Histone H3.3, Histone H3.4 (H3T), Histone H3.5, Histone H3.X and Histone H3.Y but...
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The histone fold is a structural motif located near the C-terminus of histone proteins, characterized by three alpha helices separated by two loops. This...
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In molecular biology, a histone octamer is the eight-protein complex found at the center of a nucleosome core particle. It consists of two copies of each...
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molecular biology, a chromatosome is a result of histone H1 binding to a nucleosome, which contains a histone octamer and DNA. The chromatosome contains 166...
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remodeling is principally carried out by 1) covalent histone modifications by specific enzymes, e.g., histone acetyltransferases (HATs), deacetylases, methyltransferases...
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Histone methyltransferases (HMT) are histone-modifying enzymes (e.g., histone-lysine N-methyltransferases and histone-arginine N-methyltransferases),...
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Histone H4 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a...
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Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are chemical compounds that inhibit histone deacetylases. Since deacetylation of histones...
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Histone-modifying enzymes are enzymes involved in the modification of histone substrates after protein translation and affect cellular processes including...
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Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. The other histone proteins are: H1, H2B...
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proteins which remain after the histones have been removed, are classified as non-histone proteins. The non-histone proteins, are a large group of heterogeneous...
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Histone H2A.Z is a protein encoded by the H2AZ1 gene in humans. Function Histones are basic nuclear proteins that are responsible for the nucleosome structure...
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The Histone Database is a comprehensive database of histone protein sequences including histone variants, classified by histone types and variants, maintained...
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H3K4me3 (section Understanding histone modifications)
modification to the DNA packaging protein Histone H3 that indicates tri-methylation at the 4th lysine residue of the histone H3 protein and is often involved in...
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Similar to other histone proteins, histone H2B has a distinct histone fold that is optimized for histone-histone as well as histone-DNA interactions....
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S phase (section Histone synthesis)
transcription of histone genes, S-phase entry also regulates histone production at the RNA level. Instead of polyadenylated tails, canonical histone transcripts...
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H3K27me3 (section Understanding histone modifications)
modification to the DNA packaging protein histone H3. It is a mark that indicates the tri-methylation of lysine 27 on histone H3 protein. This tri-methylation...
28 KB (2,629 words) - 18:35, 18 September 2024
H3K27ac (section Histone modifications)
packaging protein histone H3. It is a mark that indicates acetylation of the lysine residue at N-terminal position 27 of the histone H3 protein. H3K27ac...
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H3F3A (redirect from Histone H3.3)
Histone H3.3 is a protein that in humans is encoded by the H3F3A and H3F3B genes. It plays an essential role in maintaining genome integrity during mammalian...
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Bacterial DNA binding protein (redirect from Dinoflagellate histone-like proteins)
commonly referred to as histone-like and have many similar traits with the eukaryotic histone proteins. Eukaryotic histones package DNA to help it to...
19 KB (2,263 words) - 01:58, 11 December 2023