Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used...

extensive, and are as follows: Azathioprine and 6-mercaptopurine: Azathioprine is metabolised to 6-mercaptopurine which in turn is inactivated by the action...

step that azathioprine undergoes in the body is the conversion to 6-mercaptopurine (6-MP; see Pharmacokinetics), which is itself an immunosuppressant prodrug...

nonenzymatically cleaved to mercaptopurine, that acts as a purine analogue and an inhibitor of DNA synthesis. Mercaptopurine itself can also be administered...

transplantation to control rejection reactions. It is nonenzymatically cleaved to mercaptopurine, a purine analogue that inhibits DNA synthesis. By preventing the clonal...

Decitabine Doxifluridine Fludarabine Fluorouracil Gemcitabine Hydroxyurea Mercaptopurine Methotrexate Nelarabine Pemetrexed Tioguanine (formerly Thioguanine)...

Health Organization's List of Essential Medicines, such as amoxicillin, mercaptopurine, pyrimethamine and zidovudine. In 2012, under prosecution by the United...

Immunosuppressive drugs used with ulcerative colitis include: Mercaptopurine, also known as 6-Mercaptopurine, 6-MP and Purinethiol. Azathioprine, also known as Imuran...

are marketed for this purpose.[citation needed] Azathioprine and 6-mercaptopurine (6-MP) are the most commonly used immunosuppressants for maintenance...

diagnosis, prognosis, and treatment, such as treatment of leukemia with 6-mercaptopurine where toxicity largely depends on polymorphisms in multiple different...

152.18 g/mol) may refer to : Mercaptopurine, an immunosuppressive drug Tisopurine, a treatment of gout "Mercaptopurine". The American Society of Health-System...

purines, and in 1950, she developed the anti-cancer drugs tioguanine and mercaptopurine.: 66  She pursued graduate studies at night school at New York University...

alcohol. The term sulfhydryl- or mercapto- is used as a prefix, e.g. mercaptopurine. Many thiols have strong odors resembling that of garlic. The odors...

ulcerative colitis with TNF blockers, as well as with azathioprine, and/or mercaptopurine. TNF inhibitors put patients at increased risk of certain opportunistic...

involved in the metabolism of 6-mercaptopurine, caution should be taken before administering allopurinol and 6-mercaptopurine, or its prodrug azathioprine...

theophylline and chemotherapeutic agents, namely azathioprine and 6-mercaptopurine, because it could increase blood plasma concentrations of these drugs...

fluorouracil, cyclophosphamide, diethylstilbestrol diphosphate, L-DOPA, mercaptopurine, mitomycin, zidovudine Type IB Metabolic tissues (liver, GI mucosal...

central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities. A number...

(Cladribine Clofarabine Fludarabine) Nelarabine Rabacfosadine Thiopurine (Mercaptopurine# Tioguanine#) Pyrimidine Thymidylate synthase inhibitor (Capecitabine#...

Folic acid antagonists (methotrexate) Purine synthesis antagonists (6-mercaptopurine, azathioprine) Pyrimidine antagonists (cytarabine) Phenytoin Nitrous...

include, but are not limited to the following: 5-Fluorouracil (5-FU) 6-Mercaptopurine (6-MP) Capecitabine (Xeloda®) Cytarabine (Ara-C®) Floxuridine Fludarabine...

McDonald, John W. D.; MacDonald, John K. (2016-05-18). "Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis". The Cochrane Database...

inducing R139C) have been linked to clinical usage of thiopurines (e.g., mercaptopurine) in acute lymphoblastic leukemia as well as inflammatory bowel diseases...

S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents and immunosuppressive drugs. Genetic...

allopurinol 315-30-0 hypoxanthine 68-94-0 C5H4N4O2 xanthine 69-89-6 C5H4N4S mercaptopurine 50-44-2 C5H4O cyclopentadienone C5H4O2 furfural C5H4O2S b-thiophenic...

treat IBD (3% of patients), including sulfasalazine, mesalamine, 6-mercaptopurine, and azathioprine. Pancreatitis may present as symptomatic (in 2%) or...

daunorubicin, doxorubicin, amrubicin, idarubicin 1953  – US FDA approves mercaptopurine (6 MP), an immunosuppressive agent 1956  – Metastatic choriocarcinoma...

receive therapy with antimetabolite drugs such as methotrexate and 6-mercaptopurine (6-MP). People who are high-risk receive higher drug doses of these...

Cladribine (also known as 2CDA or Leustatin) Etoposide Methotrexate 6-mercaptopurine Vinblastine Surgery Radiation therapy Patients and families can gain...

many purine analogues were tested, culminating in the discovery of 6-mercaptopurine (6-MP), which was subsequently shown to be a highly active antileukemic...