of GABAA receptor channels such as benzodiazepines and barbiturates, was designated GABAС receptor. Native responses of the GABAC receptor type occur...
35 KB (3,892 words) - 05:20, 16 May 2024
GABAA-rho receptor (previously known as the GABAC receptor) is a subclass of GABAA receptors composed entirely of rho (ρ) subunits. GABAA receptors including...
17 KB (1,673 words) - 04:15, 27 October 2024
A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside...
16 KB (1,590 words) - 01:49, 26 October 2023
GABAA-ρ receptors (formerly classified as GABAC receptors but now this nomenclature has been deprecated). Given the large number of GABAA receptors, a great...
55 KB (5,956 words) - 21:34, 11 October 2024
(Z)-4-Amino-2-butenoic acid (category GABAA-rho receptor agonists)
(cis-4-aminocrotonic acid) is a GABA receptor partial agonist selective for the GABAA-ρ (previously known as GABAC) subtype. cis-4-Aminocrotonic acid at...
3 KB (160 words) - 00:19, 21 October 2024
receptor was discovered and named GABAC, but recently it has been categorized as a sub-type of the GABAA receptor. Thus, the iontropic GABA receptors...
7 KB (687 words) - 19:31, 11 February 2023
Theories of general anaesthetic action (section GABAA receptor is a major target of general anesthetics)
Cys-loop receptor superfamily includes inhibitory receptors (GABAA receptors, GABAC receptors, glycine receptors) and excitatory receptors (nicotinic...
63 KB (6,813 words) - 14:04, 5 October 2024
Ligand-gated ion channel (redirect from Ionotropic receptor)
Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow...
29 KB (2,597 words) - 03:43, 7 April 2024
Allopregnanolone (category GABAA receptor positive allosteric modulators)
JH (October 2007). "Neuroactive steroids and human recombinant rho1 GABAC receptors". The Journal of Pharmacology and Experimental Therapeutics. 323 (1):...
50 KB (4,782 words) - 13:47, 19 July 2024
Aripiprazole (category D2-receptor agonists)
induce receptor conformations (i.e., facilitate receptor shapes) in such a way as to not only prevent receptor internalization (and, thus, lower receptor density)...
106 KB (9,750 words) - 20:06, 22 October 2024
binding to its receptors which include the ligand gated ion channels, GABAA and GABAC and the G-protein couple receptors GABAB. The GABAB receptor has been...
33 KB (4,007 words) - 16:01, 21 October 2024
PMID 10542332. Billups D, Hanley JG, Orme M, et al. (2001). "GABAC receptor sensitivity is modulated by interaction with MAP1B". J. Neurosci. 20...
5 KB (613 words) - 02:22, 19 October 2022
London. This project led to the description of what is now called the GABAC receptor and the award of a PhD in 1988. After a career break for family reasons...
8 KB (764 words) - 19:20, 1 October 2024
GABA(C) receptors by protein kinase C". Mol. Pharmacol. 57 (5): 847–856. PMID 10779366. Billups D, Hanley JG, Orme M, et al. (2001). "GABAC receptor sensitivity...
7 KB (944 words) - 23:13, 3 March 2023
Molecular neuroscience (section Receptors)
neurotransmitter. GABAA and GABAC receptors are known to be ionotropic, while the GABAB receptor is metabotropic. GABAA receptors mediate fast inhibitory...
26 KB (3,050 words) - 19:05, 1 April 2024
(+)-cis-2-Aminomethylcyclopropane carboxylic acid (category GABAA-rho receptor agonists)
Chebib, M (2004). "Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability". The...
3 KB (138 words) - 12:06, 18 September 2023
channels, weakly inhibits AMPA, kainate, GABAC and 5-HT3 receptors, and slightly potentiates GABAA and glycine receptors. It also has been shown to activate...
26 KB (2,427 words) - 15:22, 18 October 2024
R. (March 2007). "(3-Aminocyclopentyl)methylphosphinic acids: Novel GABAC receptor antagonists". Neuropharmacology. 52 (3): 779–787. doi:10.1016/j.neuropharm...
6 KB (565 words) - 09:30, 3 January 2024
Carla (2008). "Molecular Dynamics Simulations of GABA Binding to the GABAC Receptor: The Role of Arg104". Biophysical Journal. 95 (9): 4115–4123. Bibcode:2008BpJ...
8 KB (785 words) - 05:59, 6 January 2024
Nitrous oxide (category GABAA receptor positive allosteric modulators)
channels, weakly inhibits AMPA, kainate, GABAC and 5-HT3 receptors, and slightly potentiates GABAA and glycine receptors. It also has been shown to activate...
95 KB (9,781 words) - 14:36, 30 October 2024
N4-Chloroacetylcytosine arabinoside (category GABAA-rho receptor agonists)
Y; Liu, H; Yan, Y; Li, Y (2008). "Identification and expression of GABAC receptor in rat testis and spermatozoa". Acta Biochimica et Biophysica Sinica...
2 KB (54 words) - 15:13, 5 May 2023
splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–6135. doi:10...
3 KB (406 words) - 22:11, 3 March 2023
splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–35. doi:10...
4 KB (456 words) - 21:44, 26 November 2023
(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid (category GABAA-rho receptor antagonists)
(TPMPA) is a GABA antagonist selective for the GABAA-ρ (previously known as GABAC) subtype. Li, Shifeng; Zhang, Yunbin; Liu, Haixiong; Yan, Yuanchang; Li...
2 KB (65 words) - 12:04, 18 April 2023
splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". J. Biol. Chem. 278 (8): 6128–35. doi:10...
7 KB (879 words) - 23:22, 16 July 2024
S2CID 196600490. Billups D, Hanley JG, Orme M, Attwell D, Moss SJ (2000). "GABAC receptor sensitivity is modulated by interaction with MAP1B". J. Neurosci. 20...
9 KB (1,060 words) - 18:59, 6 July 2024
splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2". The Journal of Biological Chemistry. 278...
3 KB (359 words) - 21:44, 26 November 2023