Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Proteins responsible...
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Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses. In order for paracrine factors...
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Two-component regulatory system (redirect from Signal transduction histidine kinase)
"conspicuously absent" from animals. Two-component systems accomplish signal transduction through the phosphorylation of a response regulator (RR) by a histidine...
26 KB (2,790 words) - 01:31, 31 March 2024
promoted. The effector component of the signaling pathway begins with signal transduction. In this process, the signal, by interacting with the receptor, starts...
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G protein (redirect from G protein signaling)
their discovery of "G-proteins and the role of these proteins in signal transduction in cells". The 2000 Nobel Prize in Physiology or Medicine to Eric...
24 KB (2,754 words) - 20:56, 30 July 2024
Calcium signaling is the use of calcium ions (Ca2+) to communicate and drive intracellular processes often as a step in signal transduction. Ca2+ is important...
19 KB (2,271 words) - 18:47, 25 March 2024
Ethylene signaling pathway is a signal transduction in plant cells to regulate important growth and developmental processes. Acting as a plant hormone...
24 KB (2,898 words) - 12:51, 6 July 2024
Hormone (redirect from Hormone signalling)
protein. Relay and amplification of the received hormonal signal via a signal transduction process: This then leads to a cellular response. The reaction...
40 KB (4,214 words) - 20:12, 18 August 2024
Cell surface receptor (category Cell signaling)
changes in the metabolism and activity of a cell. In the process of signal transduction, ligand binding affects a cascading chemical change through the cell...
21 KB (2,456 words) - 22:14, 21 November 2023
Functional selectivity (category Signal transduction)
agonism”, “biased signaling”, "ligand bias" and “differential engagement”) is the ligand-dependent selectivity for certain signal transduction pathways relative...
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GRB2 (category Signal transduction)
protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the...
82 KB (9,365 words) - 15:39, 31 March 2024
resource of signal transduction pathways in humans Artavanis-Tsakonas S, Rand MD, Lake RJ (April 1999). "Notch signaling: cell fate control and signal integration...
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Temporal feedback (category Signal transduction)
trigger, polarization in budding yeast, mammalian calcium signal transduction, EGF receptor signaling, platelet activation, and Xenopus oocyte maturation are...
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G protein-coupled receptor (category Signal transduction)
principal signal transduction pathways involving the G protein-coupled receptors: the cAMP signal pathway and the phosphatidylinositol signal pathway....
82 KB (9,384 words) - 18:56, 11 June 2024
Organ of Corti (section Auditory transduction)
strip of epithelial cells allows for transduction of auditory signals into nerve impulses' action potential. Transduction occurs through vibrations of structures...
17 KB (2,095 words) - 05:40, 26 October 2023
Because certain signal transduction pathways oppose the STAT3-Ser/Hes3 signaling axis, blockers (inhibitors) of these signal transduction pathways promote...
26 KB (3,347 words) - 03:17, 6 August 2024
independent MAP kinase signal transduction pathways. The acronym MEK derives from MAPK/ERK Kinase. MEK is a member of the MAPK signaling cascade that is activated...
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Toll-like receptor (redirect from TLR signalling pathway)
immune mechanisms on signal transduction. The fly response to fungal or bacterial infection occurs through two distinct signalling cascades, one of which...
61 KB (6,763 words) - 10:28, 1 August 2024
Sphingomyelin (section Signal transduction)
significant roles in signaling pathways: the degradation and synthesis of sphingomyelin produce important second messengers for signal transduction. Sphingomyelin...
17 KB (1,972 words) - 21:12, 19 May 2024
Imd pathway (category Signal transduction)
The Imd pathway is a broadly-conserved NF-κB immune signalling pathway of insects and some arthropods that regulates a potent antibacterial defence response...
23 KB (2,455 words) - 19:21, 2 April 2024
Glycoprotein 130 (redirect from Interleukin 6 signal transducer)
often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement. As with other type I cytokine receptors...
18 KB (2,202 words) - 01:16, 14 June 2024
GTPase (category Signal transduction)
fundamental cellular processes. Examples of these roles include: Signal transduction in response to activation of cell surface receptors, including transmembrane...
20 KB (2,306 words) - 18:17, 15 July 2024
Biochemical cascade (redirect from Signaling cascade)
intracellular signaling cascades, termed signal transduction pathways, that regulate specific cellular functions. Each signal transduction occurs with a...
99 KB (11,432 words) - 18:01, 29 April 2024
ANKK1 (category Signal transduction)
protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene contains a single nucleotide polymorphism that...
9 KB (1,105 words) - 16:23, 29 January 2023
Yoshimura, Akihiko (23 December 2002). "Control mechanism of JAK/STAT signal transduction pathway". FEBS Letters. 534 (1–3): 190–196. doi:10.1016/s0014-5793(02)03842-5...
62 KB (6,841 words) - 23:00, 17 August 2024
called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily...
34 KB (4,040 words) - 14:34, 19 July 2024
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger (called the autocrine agent) that binds to autocrine...
18 KB (2,105 words) - 01:40, 20 August 2024
PI3K/AKT/mTOR pathway (category Signal transduction)
inhibition: co-targeted therapeutic approaches in prostate cancer". Signal Transduction and Targeted Therapy. 5: 7. doi:10.1038/s41392-020-0109-y. ISSN 2059-3635...
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PMID 17444812. Kinnamon SC, Finger TE (2019). "Recent advances in taste transduction and signaling". F1000Research. 8: 2117. doi:10.12688/f1000research.21099.1....
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Peripheral chemoreceptors (section Signal transduction)
post-transduction signal processing that differentiates their responses. However, little is known about the specifics of either of these signaling mechanisms...
22 KB (2,643 words) - 18:11, 21 January 2024