Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those...
44 KB (3,710 words) - 19:17, 13 January 2025
Ticagrelor (section With clopidogrel)
whether clopidogrel is significantly influenced by such variants). Ticagrelor was found to result in a lower risk of stroke at 90 days than clopidogrel, which...
33 KB (3,133 words) - 06:31, 11 November 2024
clopidogrel to prevent these events. This interaction is possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4. Clopidogrel is...
42 KB (3,798 words) - 19:43, 13 January 2025
PCI. Prasugrel is associated with a higher bleeding risk compared to clopidogrel but has demonstrated superiority in reducing the composite endpoint of...
21 KB (2,024 words) - 11:42, 21 October 2024
ticlopidine but due to adverse effects it is not much used today. Ticlopidine, clopidogrel and prasugrel (Efient) are all thienopyridines that cause irreversible...
46 KB (5,282 words) - 08:16, 30 March 2024
extended-release dipyridamole, or clopidogrel alone. Clopidogrel and aspirin have similar efficacies and side effect profiles. Clopidogrel is more expensive and has...
45 KB (5,126 words) - 12:30, 17 November 2024
increase if they are used concomitantly with esomeprazole. Conversely, clopidogrel (Plavix) is an inactive prodrug that partially depends on CYP2C19 for...
31 KB (2,777 words) - 08:32, 19 October 2024
drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix), drugs that treat pain associated with ulcers, such as omeprazole...
39 KB (3,879 words) - 02:14, 11 August 2024
therapy. Often a combination of aspirin plus an ADP/P2Y inhibitor (such as clopidogrel, prasugrel, ticagrelor, or another) is used to obtain greater effectiveness...
18 KB (1,752 words) - 10:58, 11 August 2024
antiplatelet therapy (DAPT) which consists of a P2Y12 inhibitor, such as clopidogrel, which is taken at the same time as acetylsalicylic acid (aspirin). Dual...
38 KB (4,158 words) - 20:05, 25 August 2024
continued indefinitely, as well as another antiplatelet agent such as clopidogrel or ticagrelor ("dual antiplatelet therapy" or DAPT) for up to twelve...
129 KB (13,819 words) - 06:45, 5 January 2025
expensive. Both aspirin and clopidogrel may be useful in the first few weeks after a minor stroke or high-risk TIA. Clopidogrel has less side effects than...
187 KB (20,650 words) - 16:09, 10 January 2025
desirable. With the advent of newer and safer antiplatelet drugs such as clopidogrel and ticagrelor, its use remained limited. It was patented in 1973 and...
18 KB (1,724 words) - 08:54, 9 September 2024
BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel (AXIOMATIC-SSP)". ClinicalTrial.gov. U.S. National Library of Medicine...
4 KB (173 words) - 05:43, 28 June 2023
time. The risk of bleeding increases with the concurrent medications clopidogrel, cefoperazone, valproic acid, cefotetan, eptifibatide, tirofiban, and...
31 KB (2,684 words) - 19:41, 14 January 2025
patients presenting after cerebral ischemia. A triple therapy of aspirin, clopidogrel, and dipyridamole has been investigated, but this combination led to...
11 KB (891 words) - 17:40, 20 November 2024
risk may still find the potential benefits worth the associated risks. Clopidogrel plus aspirin (dual anti-platelet therapy) reduces cardiovascular events...
107 KB (10,943 words) - 21:17, 1 January 2025
medications that are affected include bisphosphonate derivatives, fluconazole, clopidogrel, and methotrexate. The mechanism of action of pantoprazole is to inhibit...
35 KB (2,695 words) - 07:35, 14 January 2025
of the heart's muscle cells. Antiplatelet drugs such as aspirin and clopidogrel can reduce platelet aggregation at the unstable atherosclerotic plaque...
14 KB (1,347 words) - 07:38, 31 August 2024
AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
32 KB (3,305 words) - 19:08, 12 December 2024
that G6PD deficiency could reduce the antiplatelet efficacy of clopidogrel (clopidogrel resistance). G6PD deficiency is the second most common human enzyme...
38 KB (3,970 words) - 13:02, 15 January 2025
AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
53 KB (5,257 words) - 15:53, 10 January 2025
AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
79 KB (7,691 words) - 01:26, 17 January 2025
aggregation and endothelial adherence. Platelet activation by ADP (blocked by clopidogrel) leads to the aforementioned conformational change in platelet gpIIb/IIIa...
5 KB (500 words) - 06:24, 21 December 2023
repaglinide and may lead to hypoglycemia. Co-administration of repaglinide and clopidogrel (a CYP2C8 inhibitor) may lead to a significant decrease in blood glucose...
10 KB (990 words) - 13:31, 19 December 2023
adenosine diphosphate-mediated platelet activation and aggregation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring...
15 KB (1,150 words) - 05:23, 3 March 2024
classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the...
16 KB (1,937 words) - 03:19, 16 January 2025
Antithrombotic therapy consists of antiplatelet agents, such as aspirin or clopidogrel, or anticoagulants, such as heparin or DOACs, depending on the indication...
11 KB (1,170 words) - 23:56, 26 June 2024
coronary stent thrombosis and strokes. Drugs in this class include: clopidogrel (Plavix), prasugrel (Effient), and ticlopidine (Ticlid). Tinoridine was...
2 KB (233 words) - 01:13, 30 May 2023
AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
32 KB (3,343 words) - 07:33, 30 December 2024