with everolimus.[medical citation needed] A phase IIa randomized, placebo-controlled everolimus clinical trial published in 2014 showed that everolimus improved...
27 KB (2,534 words) - 20:49, 4 October 2024
MTOR inhibitors (section Everolimus)
responses were noted. Everolimus is the second novel Rapamycin analog. Compared with the parent compound rapamycin, everolimus is more selective for the...
57 KB (6,280 words) - 19:28, 19 September 2024
Everolimus also showed evidence of effectiveness at treating epilepsy in some people with TSC. In 2017, the European Commission approved everolimus for...
50 KB (5,493 words) - 16:48, 12 July 2024
carcinoma over everolimus in 2015 and was approved by the FDA. Cabozantinib also demonstrated an overall survival benefit over everolimus and was approved...
56 KB (5,187 words) - 04:02, 20 September 2024
US Food and Drug Administration (FDA) approved it (in combination with everolimus) for the treatment of advanced renal cell carcinoma following one prior...
11 KB (934 words) - 11:38, 21 October 2024
prednisone, mycophenolate, cyclophosphamide, ciclosporin, tacrolimus, everolimus, thymoglobulin and sirolimus. Newer, so-called "biologic drugs" or monoclonal...
25 KB (2,838 words) - 02:41, 5 October 2024
PanNETs by the FDA based on improved progression-free survival (PFS): everolimus (Afinitor) is labeled for treatment of progressive neuroendocrine tumors...
28 KB (2,471 words) - 07:39, 19 October 2024
"Temporal trends in adverse events after everolimus-eluting bioresorbable vascular scaffold versus everolimus-eluting metallic stent implantation: A meta-analysis...
22 KB (2,555 words) - 08:28, 16 June 2024
Immunosuppressive drug (section Everolimus)
antibodies. It is also active against tumors that are PI3K/AKT/mTOR-dependent. Everolimus is an analog of sirolimus and also is an mTOR inhibitor. Zotarolimus is...
29 KB (3,378 words) - 02:54, 25 September 2024
immunoassay and latex agglutination turbidimetric immunoassay for evaluation of everolimus blood concentrations in renal transplant patients". Journal of Clinical...
20 KB (2,242 words) - 13:38, 9 October 2024
to shrink or stabilize subependymal giant cell tumors: rapamycin and everolimus. These both belong to the mTOR inhibitor class of immunosuppressants,...
5 KB (477 words) - 03:32, 19 February 2024
avoided through the use of alternate dosing regimens or analogs such as everolimus or temsirolimus. Lung toxicity is a serious complication associated with...
70 KB (6,960 words) - 14:00, 21 October 2024
(Nimotuzumab), BLISTO (Glimepiride + Metformin), CANMAb (Trastuzumab), Evertor (Everolimus), TACROGRAF (Tacrolimus), ALZUMAb (Itolizumab) and KRABEVA (Bevacizumab)...
31 KB (2,675 words) - 19:26, 20 October 2024
effective. In patients who continue to be refractory, mTOR inhibitors such as everolimus. The TPH inhibitor telotristat ethyl may be useful in controlling diarrhea...
17 KB (1,812 words) - 00:11, 31 August 2024
amenable to surgical removal and is causing symptoms, targeted therapy with everolimus or sunitinib can reduce symptoms and slow progression of the disease....
122 KB (12,840 words) - 02:36, 19 October 2024
"Therapeutic Response of CCKBR-Positive Tumors to Combinatory Treatment with Everolimus and the Radiolabeled Minigastrin Analogue [177Lu]Lu-PP-F11N". Pharmaceutics...
7 KB (605 words) - 18:43, 1 January 2024
(reserpine/dihydralazine/hydrochlorothiazide) Hypertension Afinitor/Certican/Zortress (everolimus) Prevention of transplant rejection, various cancers 797 2012 80% Amturnide...
144 KB (12,145 words) - 21:14, 28 September 2024
having haemorrhages, 20% of them have life-threatening haemorrhages. Everolimus is US Food and Drug Administration-approved for the treatment of angiomyolipomas...
17 KB (1,884 words) - 05:41, 29 August 2024
transplantation and on detection of CAV. Medications including sirolimus and everolimus can slow disease progression. A repeat heart transplantation may be required...
21 KB (1,955 words) - 09:30, 6 October 2024
approach of choice for AMLs that can be managed by less invasive means. Everolimus is approved by the US Food and Drug Administration (FDA) for AML treatment...
100 KB (11,094 words) - 13:43, 12 September 2024
Phenobarbital Primidone Digoxin Lidocaine Ciclosporin Tacrolimus Sirolimus Everolimus Mycophenolate Gentamicin Tobramycin Amikacin Vancomycin Bronchodilator...
46 KB (4,510 words) - 13:42, 23 September 2024
1960-11-022 November 1960 1955 1962 ethotoin Peganone 1957-04-2222 April 1957 everolimus Afinitor/Votubia 2009-03-3030 January 2009 felbamate Felbatol 1993-07-2929...
70 KB (5,714 words) - 11:37, 30 September 2024
was criticism of delays in deciding on a policy for the prescription of Everolimus in the treatment of tuberous sclerosis. Twenty doctors addressed a letter...
21 KB (2,237 words) - 17:12, 18 October 2024
FDA-approved drug-eluting stents use sirolimus (also known as rapamycin), everolimus and zotarolimus. Biolimus A9-eluting stents, which utilize biodegradable...
48 KB (5,360 words) - 06:42, 22 September 2024
mTOR inhibitors used in the treatment of human cancers, temsirolimus and everolimus. mTOR inhibitors have found use in the treatment of a variety of malignancies...
119 KB (12,658 words) - 19:25, 19 September 2024
10% in strongly positive SRSS carcinoid tumors. Targeted therapy with everolimus (Afinitor) and sunitinib (Sutent) is approved by the FDA in unresectable...
87 KB (8,009 words) - 05:16, 19 October 2024
trial of SGN-75 (INN: vorsetuzumab mafodotin) for use in combination with everolimus in patients with renal cell carcinoma 9 October: milestone achievement...
35 KB (3,161 words) - 10:23, 14 October 2024
IL-1 receptor antagonists Anakinra mTOR Everolimus Ridaforolimus Sirolimus Temsirolimus Umirolimus Zotarolimus...
7 KB (299 words) - 13:45, 27 April 2024
PN, Rini BI, Donskov F, et al. (November 2015). "Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma". The New England Journal of Medicine...
21 KB (1,640 words) - 06:51, 18 September 2024
respond to a third sequential therapy as well. Adding an mTOR inhibitor, everolimus, can further slow the tumors' progression. Those with HER2-positive metastatic...
135 KB (15,182 words) - 15:11, 20 October 2024