• Thumbnail for Raltegravir
    Raltegravir, sold under the brand name Isentress, is an antiretroviral medication used, together with other medication, to treat HIV/AIDS. It may also...
    17 KB (1,458 words) - 17:06, 24 September 2024
  • for raltegravir (brand name Isentress). Research published at the time supported the conclusion that "[for people living with HIV,] raltegravir plus...
    6 KB (622 words) - 17:42, 23 December 2023
  • Lamivudine/raltegravir, sold under the brand name Dutrebis, is a fixed-dose combination antiretroviral medication used in the treatment of HIV/AIDS. It...
    3 KB (136 words) - 19:50, 20 December 2023
  • of tenofovir disoproxil to be taken once daily, and 400 mg pills of raltegravir to be taken twice daily. People initiating nPEP treatment typically receive...
    31 KB (3,370 words) - 15:50, 1 September 2024
  • Indinavir Lamivudine (3TC) Lopinavir Maraviroc Nelfinavir Nevirapine Raltegravir Ritonavir Saquinavir Tenofovir Tipranavir Zalcitabine (ddC) Zidovudine...
    26 KB (1,722 words) - 09:50, 2 November 2024
  • Thumbnail for Oxadiazole
    all known and appear in a variety of pharmaceutical drugs including raltegravir, butalamine, fasiplon, oxolamine, and pleconaril. The 1,2,3-isomer is...
    2 KB (152 words) - 20:09, 22 July 2019
  • Zanamivir J05AH02 Oseltamivir J05AH03 Peramivir J05AH04 Laninamivir J05AJ01 Raltegravir J05AJ02 Elvitegravir J05AJ03 Dolutegravir J05AJ04 Cabotegravir J05AP01...
    6 KB (538 words) - 04:59, 18 December 2023
  • Darunavir Lopinavir/ritonavir (lopinavir + ritonavir) Ritonavir Dolutegravir Raltegravir Abacavir/lamivudine (abacavir + lamivudine) Dolutegravir/lamivudine/tenofovir...
    67 KB (4,822 words) - 18:15, 10 November 2024
  • under clinical trial,[when?] and raltegravir became the first to receive FDA approval in October 2007. Raltegravir has two metal binding groups that...
    133 KB (15,784 words) - 05:42, 17 September 2024
  • Thumbnail for Merck & Co.
    2020 revenue. Other major products by the company include Isentress (raltegravir), an antiretroviral medication used to treat HIV/AIDS that had $857 million...
    99 KB (9,725 words) - 22:20, 5 November 2024
  • Thumbnail for HIV/AIDS
    United States consists of three medications—tenofovir, emtricitabine and raltegravir—as this may reduce the risk further. PEP treatment is recommended after...
    211 KB (21,185 words) - 04:17, 28 October 2024
  • 3.54% Johnson & Johnson HIV infection Jun-2006 Mon-20XX 61 Isentress Raltegravir 248,924 0.72% Merck & Co., Inc. HIV Infection Dec-1998 Mon-20XX 62 Janumet...
    29 KB (281 words) - 06:29, 12 August 2024
  • rafoxanide (INN) ralitoline (INN) ralitrexed (INN) raloxifene (INN) raltegravir (USAN) ramatroban (INN) ramciclane (INN) ramelteon (USAN) ramifenazone...
    5 KB (286 words) - 04:52, 6 September 2024
  • Pleconaril Picornavirus Schering-Plough Podophyllotoxin Genital wart Raltegravir HIV Integrase inhibitor Remdesivir COVID-19 viral RNA polymerase inhibitor...
    13 KB (513 words) - 14:31, 4 May 2024
  • Thumbnail for Cabotegravir/rilpivirine
    Bictegravir (BIC) Cabotegravir (CAB) Dolutegravir (DTG)# Elvitegravir (EVG) Raltegravir (RAL)# BI 224436† MK-2048† Maturation inhibitors Bevirimat† BMS-955176§...
    15 KB (1,230 words) - 02:38, 16 July 2024
  • Laboratory, Chilton, Oxfordshire, England, UK; a national research lab Raltegravir, an antiretroviral medication Zearalenone, an estrogenic metabolite Ral...
    2 KB (348 words) - 14:53, 13 June 2023
  • Thumbnail for Dapivirine Ring
    Bictegravir (BIC) Cabotegravir (CAB) Dolutegravir (DTG)# Elvitegravir (EVG) Raltegravir (RAL)# BI 224436† MK-2048† Maturation inhibitors Bevirimat† BMS-955176§...
    28 KB (2,975 words) - 02:18, 11 August 2024
  • Thumbnail for 1,3,4-Oxadiazole
    organic chemistry, but many of its derivatives are important. For example, raltegravir is an HIV drug which contains an 1,3,4-oxadiazole ring. Other pharmaceutical...
    4 KB (303 words) - 23:09, 2 October 2021
  • Thumbnail for Antiviral drug
    into the host cell genome. Examples of integrase inhibitors include raltegravir, elvitegravir, and dolutegravir. Once a virus genome becomes operational...
    55 KB (6,733 words) - 21:23, 24 October 2024
  • Thumbnail for Integrase
    Food and Drug Administration (U.S.) approved the integrase inhibitor Raltegravir (MK-0518, brand name Isentress). The second integrase inhibitor, elvitegravir...
    12 KB (1,288 words) - 02:08, 1 June 2024
  • Thumbnail for Drug design
    peptide HIV entry inhibitor Nonbenzodiazepines like zolpidem and zopiclone Raltegravir, an HIV integrase inhibitor SSRIs (selective serotonin reuptake inhibitors)...
    44 KB (5,022 words) - 08:47, 12 October 2024
  • integration, eventually leading to HIV integrase inhibitors such as raltegravir in 2008. Additionally, Montano et al. created a crystal structure of...
    7 KB (781 words) - 15:48, 31 March 2024
  • Thumbnail for Resistance mutation (virology)
    PMC 2586907. PMID 18558886. Hicks, Charles; Gulick, Roy M. (2009-04-01). "Raltegravir: The First HIV Type 1 Integrase Inhibitor". Clinical Infectious Diseases...
    12 KB (1,466 words) - 07:15, 22 August 2024
  • Thumbnail for MK-2048
    inhibitor, raltegravir, in that "MK-2048 has a dissociation half-life of 32 hours on wild-type integrase—more than four times that of raltegravir", and its...
    5 KB (393 words) - 21:08, 27 May 2024
  • of the first HIV integrase inhibitor to gain FDA approval, Isentress (raltegravir). Her lab also determined these inhibitors' mechanism of action and ways...
    14 KB (1,465 words) - 05:55, 16 April 2024
  • Thumbnail for Charles Flexner
    Flexner, C.; Goh, B. C. (2011). "Simultaneous determination of raltegravir and raltegravir glucuronide in human plasma by liquid chromatography-tandem mass...
    13 KB (1,572 words) - 23:39, 18 July 2024
  • Thumbnail for Sofosbuvir
    ciclosporin, darunavir/ritonavir, efavirenz, emtricitabine, methadone, raltegravir, rilpivirine, tacrolimus, or tenofovir disoproxil, were evaluated in...
    64 KB (5,828 words) - 23:44, 21 October 2024
  • of drugs used in the treatment of HIV. The first integrase inhibitor, raltegravir, was approved in 2007 and other drugs were in clinical trials in 2011...
    32 KB (4,154 words) - 08:34, 29 November 2023
  • Darunavir Lopinavir/ritonavir (lopinavir + ritonavir) Ritonavir Dolutegravir Raltegravir Abacavir/lamivudine (abacavir + lamivudine) Lamivudine/zidovudine (lamivudine...
    38 KB (2,574 words) - 03:03, 15 July 2024
  • Thumbnail for Nimâ Machouf
    Lessard, Serge Dufresne, and Richard Lalonde. "Switch from enfuvirtide to raltegravir in patients with undetectable viral load: efficacy and safety at 24 weeks...
    10 KB (679 words) - 16:53, 26 September 2024