The 2000 LPGA Tour was the 51st season since the LPGA Tour officially began in 1950. The season ran from January 13 to November 19. The season consisted of 36 official money events. Karrie Webb won the most tournaments, seven. She also led the money list with earnings of $1,876,853.
The U.S. Women's Open was the first tournament with a purse over $2,000,00 and a winner's share of $500,000. This was the last season that the du Maurier Classic (now known as the Canadian Women's Open) was considered an LPGA major. It was replaced as a major by the Women's British Open in 2001. There were seven first-time winners in 2000: Dorothy Delasin, Sophie Gustafson, Lorie Kane, Laurel Kean, Janice Moodie, Grace Park, and Charlotta Sörenstam.
The tournament results, leaders, and award winners are listed below.
The following table shows all the official money events for the 2000 season.[1] "Date" is the ending date of the tournament. The numbers in parentheses after the winners' names are the number of wins they had on the tour up to and including that event. Majors are shown in bold.
| Date | Tournament | Location | Winner | Score | Purse ($) | 1st prize ($) |
| Jan 16 | The Office Depot | Florida |  Karrie Webb (17) | 281 (−7) | 750,000 | 112,500 |
| Jan 23 | Subaru Memorial of Naples | Florida |  Nancy Scranton (3) | 275 (−13) | 850,000 | 127,500 |
| Feb 13 | Los Angeles Women's Championship | California |  Laura Davies (18) | 211 (−5) | 750,000 | 112,500 |
| Feb 19 | Cup Noodles Hawaiian Ladies Open | Hawaii | Betsy King (32) | 204 (−12) | 650,000 | 97,500 |
| Feb 27 | Australian Ladies Masters | Australia | Karrie Webb (18) | 274 (−14) | 750,000 | 112,500 |
| Mar 4 | LPGA Takefuji Classic | Hawaii | Karrie Webb (19) | 207 (−9) | 800,000 | 120,000 |
| Mar 12 | Welch's/Circle K Championship | Arizona |  Annika Sörenstam (19) | 269 (−19) | 700,000 | 105,000 |
| Mar 19 | Standard Register PING | Arizona | Charlotta Sörenstam (1) | 276 (−12) | 850,000 | 127,500 |
| Mar 26 | Nabisco Championship | California | Karrie Webb (20) | 274 (−14) | 1,250,000 | 187,500 |
| Apr 16 | Longs Drugs Challenge | California | Juli Inkster (23) | 275 (−13) | 700,000 | 105,000 |
| Apr 30 | Chick-fil-A Charity Championship | Georgia | Sophie Gustafson (1) | 206 (−10) | 900,000 | 135,000 |
| May 7 | The Philips Invitational | Texas | Laura Davies (19) | 275 (−5) | 850,000 | 127,500 |
| May 14 | Electrolux USA Championship | Tennessee | Pat Hurst (3) | 275 (−13) | 800,000 | 120,000 |
| May 21 | Firstar LPGA Classic | Ohio | Annika Sörenstam (20) | 197 (−19) | 650,000 | 97,500 |
| May 28 | LPGA Corning Classic | New York | Betsy King (33) | 276 (−12) | 800,000 | 120,000 |
| Jun 4 | Kathy Ireland Greens.com LPGA Classic | South Carolina |  Grace Park (1) | 274 (−14) | 750,000 | 112,500 |
| Jun 11 | Wegmans Rochester International | New York | Meg Mallon (12) | 280 (−8) | 1,000,000 | 150,000 |
| Jun 17 | Evian Masters | France | Annika Sörenstam (21) | 276 (−12) | 1,800,000 | 270,000 |
| Jun 25 | McDonald's LPGA Championship | Delaware | Juli Inkster (24) | 281 (−3) | 1,400,000 | 210,000 |
| Jul 2 | ShopRite LPGA Classic | New Jersey |  Janice Moodie (1) | 203 (−10) | 1,100,000 | 165,000 |
| Jul 9 | Jamie Farr Kroger Classic | Ohio | Annika Sörenstam (22) | 274 (−10) | 1,000,000 | 150,000 |
| Jul 16 | Japan Airlines Big Apple Classic | New York | Annika Sörenstam (23) | 206 (−7) | 900,000 | 135,000 |
| Jul 23 | U.S. Women's Open | Illinois | Karrie Webb (21) | 282 (−6) | 2,750,000 | 500,000 |
| Jul 30 | Giant Eagle LPGA Classic | Ohio | Dorothy Delasin (1) | 205 (−11) | 1,000,000 | 150,000 |
| Aug 6 | Michelob Light Classic | Missouri |  Lorie Kane (1) | 205 (−11) | 800,000 | 120,000 |
| Aug 13 | du Maurier Classic | Canada | Meg Mallon (13) | 282 (−6) | 1,200,000 | 180,000 |
| Aug 20 | Weetabix Women's British Open | England | Sophie Gustafson (2) | 282 (−10) | 1,250,000 | 178,000 |
| Aug 27 | Oldsmobile Classic | Michigan | Karrie Webb (22) | 265 (−23) | 750,000 | 112,500 |
| Sep 3 | State Farm Rail Classic | Illinois | Laurel Kean (1) | 198 (−18) | 900,000 | 135,000 |
| Sep 10 | First Union Betsy King Classic | Pennsylvania | Michele Redman (2) | 202 (−14) | 800,000 | 120,000 |
| Sep 24 | Safeway LPGA Golf Championship | Oregon | Mi Hyun Kim (3) | 215 (−1) | 800,000 | 120,000 |
| Oct 1 | New Albany Golf Classic | Ohio | Lorie Kane (2) | 277 (−11) | 1,000,000 | 150,000 |
| Oct 15 | Samsung World Championship | California | Juli Inkster (25) | 274 (−14) | 725,000 | 152,000 |
| Oct 22 | AFLAC Champions | Alabama | Karrie Webb (23) | 273 (−15) | 750,000 | 122,000 |
| Nov 5 | Mizuno Classic | Japan | Lorie Kane (3) | 204 (−12) | 850,000 | 127,500 |
| Nov 19 | Arch Wireless Championship | Florida | Dottie Pepper (17) | 279 (−9) | 1,000,000 | 215,000 |
Money List leaders
| Rank | Player | Country | Earnings ($) | Events |
| 1 | Karrie Webb | Australia | 1,876,853 | 22 |
| 2 | Annika Sörenstam | Sweden | 1,404,948 | 22 |
| 3 | Meg Mallon |  United States | 1,146,360 | 26 |
| 4 | Juli Inkster | United States | 980,330 | 19 |
| 5 | Lorie Kane | Canada | 929,189 | 30 |
| 6 | Pat Hurst | United States | 840,161 | 26 |
| 7 | Mi Hyun Kim | South Korea | 825,720 | 27 |
| 8 | Dottie Pepper | United States | 786,695 | 19 |
| 9 | Rosie Jones | United States | 643,054 | 25 |
| 10 | Michele Redman | United States | 585,694 | 28 |
Full 2000 Official Money List
French
Deutsch
Karrie Webb
Dorothy Delasin
Sweden
United States
Canada
South Korea