2009 swine flu pandemic timeline

This article covers the chronology of the 2009 novel influenza A (H1N1) pandemic.^[1] Flag icons denote the first announcements of confirmed cases by the respective nation-states, their first deaths (and other major events such as their first intergenerational cases, cases of zoonosis, and the start of national vaccination campaigns), and relevant sessions and announcements of the World Health Organization (WHO), the European Union (and its agency the European Centre for Disease Prevention and Control), and the U.S. Centers for Disease Control (CDC).

Unless otherwise noted, references to terms like S-OIV, H1N1 and such, all refer to this new A(H1N1) strain and not to sundry other strains of H1N1 which are endemic in humans, birds and pigs.

Take note that the date of the first confirmations of the disease or any event in a country may be before or after the date of the events in local time because of the International Dateline.

Mexico In La Gloria, Veracruz 60% of the town's population is sickened by a respiratory illness of unknown provenance. The government of Mexico believes it to be caused by H3N2 influenza, though at least one patient in La Gloria tested positive for A/H1N1. Two babies died in the outbreak but both were buried without testing.^[2]

United States In the ninth week of its routine influenza surveillance, the CDC reports on FluView that thirty-five states have reported widespread influenza activity, and 14 states have reported regional activity, but that although the rate of activity was high, that the proportion of deaths attributed to pneumonia and influenza (P&I) was below the epidemic threshold.^[3]

United States The CDC reports on the 10th week of FluView that thirty states reported widespread influenza activity and 18 states reported regional activity.^[4]

Mexico Earliest known onset of a case that is later to be confirmed as Swine-Origin Influenza A (H1N1) Virus Infection.^[5][6]

United States CDC FluView, Week 11: Widespread influenza activity in twenty-four states; regional activity in 19. Influenza activity continues to decrease.^[7]

United States Earliest known onset of a USA case later confirmed as swine flu, that of a nine-year-old girl residing in Imperial County, California.^[8][9] Thirteen states reported widespread influenza activity and 19 reported regional activity on the CDC's FluView, Week 12.^[10]

United States A sample is collected from a nine-year-old female patient which is later confirmed to contain the novel virus strain (genetically sequenced as A/California/05/2009(H1N1)).^[11][12]

United States Onset of illness for a ten-year-old boy residing in San Diego County, California; his case is eventually the first to be confirmed as swine flu in the US.^[9]

United States A nasopharyngeal swab is collected from a ten-year-old male patient in San Diego County, later confirmed as containing the novel virus and the first organism of that strain to be completely sequenced (A/California/04/2009(H1N1)).^[9][11][13]

Mexico In La Gloria, Veracruz, a four-year-old boy falls ill at the end of the outbreak. Only his sample, which was eventually sent abroad, tested positive for A(H1N1). Veracruz officials state that there were no plans to exhume the bodies of two infants who died in the outbreak.^[2]

United States CDC FluView, Week 13: Widespread influenza activity in four states, regional activity in 18.^[14]

European Union The media monitoring website MedISys reports on a Mexican article about the epidemiological alert.^[15][16]

Mexico Public health authorities begin investigating unusual cases of pneumonia.^[17] 400 people had reportedly sought treatment for pneumonia/influenza-like illness (ILI) in La Gloria the preceding week.^[17]

United States Biosurveillance firm Veratect reports the unusual respiratory illness in Mexico.^[18][19] Veratect publishes the alert "La Gloria: 'Strange' Respiratory Affects 60% of Local Population; Three Pediatric Deaths May be Associated with the Outbreak."^[17][18]

United States CDC FluView, Week 14: Widespread influenza activity in one state; regional activity in 14.^[20]

Mexico The General Directorate of Epidemiology (DGE) reports the outbreak of an ILI in a small community in Veracruz to the Pan American Health Organization (PAHO), which is the Regional Office of the World Health Organization (WHO).^[5][21] Furthermore, a 39-year-old woman dies of severe viral pneumonia in the city of San Luis Potosí; this is later believed to be the earliest known fatality related to the outbreak.^[22]

Mexico First death in Oaxaca due to what would later be identified as swine flu.^[23]

United States The U.S. Centers for Disease Control (CDC) is advised of a ten-year-old boy with a respiratory illness in San Diego County, California. Test results revealed an Influenza A virus but were negative for standard human strains. The San Diego County Health Department is notified.^[9]

United States The CDC receives its first sample from California (from the ten-year-old boy in San Diego County), and identifies the virus as a strain of swine influenza A(H1N1).^[9]

Mexico Authorities notify the PAHO of the atypical pneumonia.^[17]

United States Veratect publishes the alert "Atypical Pneumonia Cases Reported at Hospital" regarding the Oaxaca cases.^[17][18]

Mexico A case of atypical pneumonia in Oaxaca prompts enhanced national surveillance. A field investigation is started.^[5] Mexico contacts Canada to request more specialized testing.^[24]

United States The CDC receives a second sample from Southern California (taken from the nine-year-old girl in Imperial County), and again identifies the virus as a strain of swine influenza A(H1N1). The California Department of Public Health is notified.^[9]

Mexico Mexico sends 14 mucus samples to the CDC and dispatches health teams hospitals to look for patients showing severe influenza- or pneumonia-like symptoms.^[25]

United States CDC FluView, Week 15: "Nine states reported regional activity; 17 states reported local influenza activity; the District of Columbia and 22 states reported sporadic influenza activity; and two states reported no influenza activity. Seven human infections with swine influenza A (H1N1) virus have been confirmed." This is the first mention of A(H1N1) in FluView.^[26]

United States Veratect advises the CDC of the Mexican events.^[17][18] The CDC is already investigating the California and Texas cases.^[17][18][27]

United States The CDC alerts physicians to a similar novel strain of swine influenza A(H1N1) in two cases from Southern California in a Morbidity and Mortality Weekly Report Early Release on its website.^[28] Local investigations, including investigations in Texas, are already underway, and overall surveillance is enhanced.^[9][29] The Associated Press covers the alert, the first mention of the A(H1N1) outbreak in English-language news media.^[27][30][31]

Canada Canada receives the samples from Mexico for testing.^[24]

Mexico The Public Health Agency of Canada confirms Mexico cases of swine-origin influenza A (H1N1) virus (S-OIV) infection.^[5] Genetic sequence analysis reveals that the Mexican patients were infected with the same S-OIV strain detected in two California children.^[5] The PAHO is informed that a cluster in Mexico of severe respiratory illnesses has been laboratory-confirmed as S-OIV infection.^[5]

The WHO issues its first Disease Outbreak Notice on the matter, confirming the infection of a number of people in Mexico and the United States by "Swine Influenza A/H1N1 viruses... not... previously detected in pigs or humans".^[32]

Mexico The Minister of Health confirms the Mexican cases of human infection by swine influenza and states that it believes that some of these cases had resulted in death.^[33] Health authorities implement public health measures for all airport passengers and the vaccination of health care workers with seasonal influenza vaccine.^[5]

United States The CDC tells a press conference that seven of the 14 Mexican samples contained the same virus strain as the known in California and Texas, and that indications suggested that containment in the USA was "not very likely".^[33] The novel strain had already been reported on the CDC's Morbidity and Mortality Weekly Report website.^[28]

WHO Under the International Health Regulations (IHR), the Emergency Committee convenes for the first time since its establishment in 2007,^[34] resulting in the WHO Director-General declaring a formal "public health emergency of international concern,"^[35][36] (PHEIC),^[37] the first ever.

The PAHO Vaccination Week In The Americas starts.^[38] The 2009 Week was planned to emphasize the vaccination of entire families, and health worker immunization.^[38]

United States First closure of an entire school district, the Schertz-Cibolo-Universal City Independent School District outside San Antonio, Texas.^[39][40]

United States United States declares a Public Health Emergency.^[41]

WHO The Emergency Committee meets for the second time. The WHO Director-General issues a statement that containment of the outbreak is not feasible, and elevates the pandemic alert from Phase 3 to Phase 4.^[42]

European Union (EU) Health Commissioner advises Europeans not to travel to the United States or Mexico unless the need is urgent. This follows the first confirmed case in Spain.^[43]

Canada First six cases confirmed, four in Nova Scotia and two in British Columbia.^[44]

Mexico First seven confirmed deaths^[45]

Spain First confirmed case of swine flu, in Almansa, and thus the first case in Europe; A(H1N1) has spread from the WHO Region of the Americas to the WHO European Region.^[46]

( ) United Kingdom First two confirmed cases, in Scotland.^[47]

WHO Confirmed cases are now extant in four of six WHO regions (see map). As of 19:15 GMT seven countries have officially reported cases of swine influenza A(H1N1) infection.^[48]

Canada Confirmed: two cases and another four in Alberta and Ontario, respectively.^[49]

Israel First confirmed case in Israel and thus the WHO Eastern Mediterranean Region (color-coded yellow), the third region to be affected.^[50]

New Zealand First three confirmed cases in New Zealand and thus the WHO Western Pacific Region (color-coded red), the fourth region to be affected.^[51]

Spain The second confirmed case in Spain, in Valencia.^[52][53]

WHO The Emergency Committee meets for the third time,^[54] and the WHO raises its pandemic alert level from Phase 4 to Phase 5, its second highest.^[55] As of 1800 GMT, nine countries have officially reported 148 cases of swine influenza A(H1N1) infection.^[56]

ASEAN ASEAN officials are looking at coordinating measures to address the potential pandemic.^[57]

EU Foreign Relations Commissioner Benita Ferrero-Waldner announces that the halt of all travel to Mexico and disinfecting all airports due to the global flu outbreak is being considered.^[58]

Austria First confirmed case.^[56]

Germany First three confirmed cases, two in Bavaria and one in Hamburg.^[59]

Spain Eight more cases raises the total in Spain to 10, including the first human-to-human intergenerational transmission^[60] (in which the patient had not recently been to Mexico but was infected by another patient who had just visited Mexico, namely his girlfriend).^[61] This is the first intergenerational transmission to be documented in Europe.

United States First death outside Mexico, a 23-month-old Mexican child hospitalized in Texas.^[62] Ninety-one confirmed cases in the US to date.^[63]

South Africa First two cases reported within South Africa, by two women that travelled in Mexico weeks earlier. The cases were confirmed on 18 June 2009.

Canada Confirmed: One more case in Toronto, and eight more cases in Nova Scotia, and Alberta bringing total to 28.^[64]

Ireland First confirmed case.^[65]

Netherlands First confirmed case, a three-year-old child.^[66] The child returned from Mexico to the Netherlands on April 27, 2009. The parents test negative for A(H1N1).

Switzerland First confirmed case.^[67]

United States Four cases are confirmed in an outbreak at the University of Delaware; another 12 cases are deemed "probable". One of the confirmed cases is a baseball player, which results in the university cancelling sporting events, a concert by rapper Young Jeezy, and other school activities.^[68]

United Kingdom Three further confirmed cases of swine flu, giving a total of eight confirmed cases.^[69]

WHO As of 0600 GMT, 11 countries have officially reported 331 cases of influenza A(H1N1) infection.^[70]

Canada 51 confirmed cases.^[71]

Hong Kong

• 300 people are placed under quarantine at a hotel for seven days due to Hong Kong's first confirmed case there.^[72]
• Chief Executive Donald Tsang raises Hong Kong's response level from "serious" to "emergency".^[73]
• The Director of Health, Dr. PY Lam, orders Metropark Hotel in Wan Chai to be isolated for seven days.^[74]

Denmark First confirmed case (in Hvidovre).^[75]

France First two confirmed cases.^[76]

Mexico begins an unprecedented five-day shutdown to fight the spread of the flu.^[77]

United Kingdom First and second case of human to human (or intergenerational) transmission within the UK confirmed.^[78]

United States 155 confirmed cases, including two at George Washington University's Thurston Hall.^[79]

WHO As of 0600 GMT 15 countries have officially reported 615 cases of influenza A(H1N1) infection.^[80]

Canada The Canadian Food Inspection Agency confirms the first human-to-animal transmission of the virus after an Albertan returns from Mexico and infects a pig farm, the first known case of (reverse) zoonosis.^[81]

China suspends flights from Mexico.^[82]

South Korea First confirmed case.^[83]

United States There are more than 430 school closures in 18 states.^[84] CDC FluView Week 17: Widespread activity in seven states, regional activity in 12.^[85]

WHO As of 0600 GMT, 17 countries have officially reported 787 cases of (A)H1N1.^[80]

Arab League Health Ministers meet in Riyadh, to discuss human and technical support to be deployed in any Arab affected place.^[86]

Canada 101 confirmed cases after seven cases in British Columbia, three in Alberta, two in Nova Scotia and Ontario, and one in Quebec were confirmed.^[87]

Colombia First confirmed case in South America.^[87]

WHO As of 06:00 GMT, 20 countries have officially reported 985 cases of influenza A (H1N1) infection.^[88][89]

Canada A girl from Edmonton, Alberta was diagnosed with a severe case of the H1N1 virus.^[90]

WHO As of 06:00 GMT, 21 countries have officially reported 1,124 cases of influenza A (H1N1) infection.^[91]

United States

• Second confirmed death, the first of a U.S. resident, a pregnant special education teacher in Texas: Judy Trunnell. The 33-year-old gives birth to her second child via Caesarian section during her eighth month of pregnancy, in a coma whilst on life support.^[92][93] Judy Trunnell had several underlying medical conditions, most notably asthma.^[94][95][96]
• Several sailors in San Diego, California fall ill (including a sailor on the USS Dubuque, which results in the cancellation of its deployment). These are the first cases in the U.S. Navy.^[97]
• As the low level of virulence of novel A(H1N1) in the U.S. becomes established, the CDC issues revised criteria for school closures, effectively ending widespread shutdowns.^[98]

WHO As of 06:00 GMT, 22 countries have officially reported 1,516 cases of influenza A (H1N1) infection.^[99]

ASEAN A special regional summit to fight possible swine flu pandemic was held in Bangkok and was attended by senior ASEAN health officials along with those from China, Japan and South Korea.^[100]

Guatemala First confirmed case, and the first in Central America.^[101][102]

Poland First confirmed case.^[103]

Sweden First confirmed case.^[104]

WHO As of 18:00 GMT, 24 countries have officially reported 2,371 cases of influenza A (H1N1) infection.^[105]

Argentina First confirmed case.^[106]

Brazil First four confirmed cases.^[107][108]

Canada Reports suggest that an elderly woman who had swine flu has died in northern Alberta, marking the first death in Canada related to swine flu.^[109] Furthermore, an unusual case of zoonosis occurred when a swine flu inspector in improper gear caught the virus from an infected pig.^[110]

Netherlands Second case confirmed, a 53-year-old woman who had recently travelled to Mexico.^[111]

USA The New England Journal of Medicine establishes its H1N1 Influenza Center on its website.^[112]

WHO As of 16:00 GMT, 25 countries have officially reported 2,500 cases of influenza A (H1N1) infection.^[113]

Japan First three confirmed cases.^[114]

Panama First confirmed case.^{[115][116][117]}

WHO As of 06:00 GMT, 29 countries have officially reported 3,440 cases of influenza A(H1N1) infection.^[118]

Australia First confirmed case.^[119]

Brazil Two cases confirmed, one of which is thought to be the first case of human-to-human infection in Brazil.^[120]

Costa Rica First confirmed death, and also the first death outside of North America.^[121][122] Three other confirmed cases, all children, were contaminated by the patient who died.^[123]

Japan 4th confirmed case, a schoolmate of the first three cases.^[124]

Norway First two confirmed cases.^[125]

United States Third confirmed death, a Washington man with underlying heart disease.^[126] Also, the USA passes Mexico in the number of confirmed cases of infection, 1693 to 1364, thus becoming the nation-state with the most laboratory-confirmed cases of infection; Canada is third with 242 cases.^[127] CDC FluView Week 18: Widespread influenza activity in eight states, regional activity in 14.^[128]

WHO As of 07:30 GMT, 29 countries have officially reported 4,379 cases of influenza A(H1N1) infection.^[129]

China First confirmed case.^[130]

WHO As of 06:00 GMT, 30 countries have officially reported 4,694 cases of influenza A(H1N1) infection.^[131]

WHO As of 06:00 GMT, 30 countries have officially reported 5,251 cases of influenza A(H1N1) infection.^[132]

Canada The first case in Yukon Territory is confirmed.^[133]

Spain 100 cases confirmed.^[134]

WHO As of 06:00 GMT, 13 May 2009, 33 countries have officially reported 5,728 cases of influenza A(H1N1) infection.^[135]

Belgium First confirmed case.^[136]

Panama 10 more cases confirmed today. Total: 39.^[137]

WHO As of 06:00 GMT, 33 countries have officially reported 6,497 cases of influenza A(H1N1) infection.^[138]

Belgium Second confirmed case.^[139]

Colombia First domestic infections with three cases confirmed. Total: 10.^[140]

WHO As of 06:00 GMT, 34 countries have officially reported 7,520 cases of influenza A(H1N1) infection.^[141]

USA Fourth and fifth deaths confirmed, that of an Arizona woman suffering from a lung condition^[142][143] and a Texas man in Corpus Christi, respectively.^[144][145]

Malaysia First confirmed case.^[146] Malaysia is the 37th country to be affected by the virus.

Panama Four new cases confirmed today. Total: 43, 23 of whom are male and 20 of whom are female. 20 of the cases are under 15 years old.^[147]

WHO As of 06:00 GMT 36 countries have officially reported 8,451 cases of influenza A(H1N1) infection.

India First case confirmed, in Hyderabad.^[148] This marks the arrival of A(H1N1) in the fifth of the WHO's six regions, the South-East Asia Region.

Japan First domestic infection confirmed, in Kobe, a male high school student with no history of travel abroad.^[149] The Kobe Festival, planned for May 16 and 17, is cancelled.^[150]

Malaysia Second confirmed case.^[151] The first patient is now showing significant improvement from the treatment.

Panama 11 new confirmed cases. 54 total.^[152]

Turkey First confirmed case, that of an American tourist flying from the United States via Amsterdam, discovered at Istanbul's Atatürk International Airport.^[153]

United States CDC FluView Week 19: Widespread influenza activity in five states, regional activity in 13.^[154]

WHO As of 06:00 GMT 37 countries have officially reported 8,480 cases of influenza A(H1N1) infection.

Panama With 54 confirmed cases, Panama occupies second place, along with Canada, for the number of cases per country.

WHO As of 06:00 GMT, 40 countries have officially reported 8,829 cases of influenza A(H1N1) infection, including 74 deaths.^[155]

ECDC The European Centre for Disease Control releases its early findings on H1N1's pandemic potential.^[156]

Japan reports 96 confirmed cases;^[157] it now ranks fourth in the world in the number of infections. Thousands of schools in 21 cities in the Hyogo and Osaka prefectures are temporarily closed.^[158][159]

USA The sixth death in the US, and the first in New York—that of an assistant principal.^[160][161]

WHO As of 06:00 GMT, 40 countries have officially reported 9,830 cases of influenza A(H1N1) infection, including 79 deaths.^[162]

United States Seventh confirmed death, that of a 44-year-old Missouri man.^[163]

Japan 191 confirmed cases; Hyogo Prefecture has the most at 111.^[164]

Norway One more case confirmed today. Total: three.^[165]

Paraguay confirmed its first case and became the 43rd affected country.^[166]

Taiwan confirmed its first case and becomes the 44th affected country.^[167]

WHO As of 06:00 GMT, 40 countries have officially reported 10,243 cases of influenza A(H1N1) infection, including 80 deaths.^[168]

United States A patient dies in Arizona,^[169] and a 22-year-old man dies in Utah,^[170] the nation's eighth and ninth H1N1 fatalities. Roughly half of the influenza viruses detected by the CDC's routine influenza surveillance systems are now that of novel A(H1N1).^[1] An unusual number of outbreaks in schools is reported.^[171]

Japan 236 confirmed cases, including the first case in Shiga Prefecture,^[172] and the cities of Hachiōji and Kawasaki in the Greater Tokyo Area. Two female high school students from Tokyo who had recently attended a Model United Nations conference in New York are presumed to have become infected abroad.^[173][174]

Norway 1 more case confirmed today. Total: 4.^[165]

WHO As of 06:00 GMT, 41 countries have officially reported 11,034 cases of influenza A(H1N1) infection, including 85 deaths.^[175]

Japan 279 confirmed cases; more than 4,800 schools are closed in the Kobe region.^[176]

WHO As of 06:00 GMT, 42 countries have officially reported 11,168 cases of influenza A(H1N1) infection, including 86 deaths.^[177]

Japan 317 confirmed, including first confirmed in Saitama Prefecture.^[178] Third confirmed in Tokyo, a 25-year-old man who visited Osaka from May 14-20th.^[179]

Philippines First case confirmed.^[180]

WHO As of 06:00 GMT, 43 countries have officially reported 12,022 cases of influenza A(H1N1) infection, including 86 deaths.^[181]

Iceland First confirmed case. 4 more cases suspected.^[182][183] United States CDC FluView Week 20: Widespread influenza activity in four states; regional activity in 11.^[184]

Australia Two more confirmed cases, which now brings the national toll to 16.^[185]

Kuwait First confirmed cases, that of 18 U.S. soldiers.^[186]

WHO As of 06:00 GMT, 46 countries have officially reported 12,515 cases of influenza A(H1N1) infection, including 91 deaths.^[187]

Australia 22 Confirmed Cases.^[188]

Ireland Second confirmed case.^[189]

WHO As of 06:00 GMT, 46 countries have officially reported 12,954 cases of influenza A(H1N1) infection, including 92 deaths.^[190]

Argentina 14 Confirmed Cases. Total: 19.^[191]

Australia 61 confirmed cases.^{[192][193][194]}

Puerto Rico First confirmed case.^[195]

WHO As of 06:00 GMT, 48 countries have officially reported 13,398 cases of influenza A(H1N1) infection, including 95 deaths^[196]

Argentina 37 cases confirmed.^[197]

Dominican Republic First two confirmed cases.^[198]

Greece confirmed two more cases.^[199]

Romania First confirmed case.^[200]

Singapore First confirmed case. A 22-year-old woman picked up the virus after visiting New York.^[201]

United Kingdom Two new cases confirmed. Total: 186.^[202]

Uruguay confirmed its first two cases.^[203]

Australia 147 confirmed cases.^[204]

Singapore Three more cases confirmed. Total confirmed cases now stands at four.^[205]

United Kingdom Seventeen more confirmed cases. Total: 203.^[206]

Bolivia First 2 cases confirmed.^[207]

Venezuela First confirmed case.^[208]

WHO As of 06:00 GMT, 53 countries have officially reported 15,510 cases of influenza A(H1N1) infection, including 99 deaths^[209]

United Kingdom 14 confirmed cases. Total: 217.^[210]

Norway One new confirmed case. Total: 5.^[165]

Hungary First confirmed case^[211]

Uruguay 4 new confirmed cases. Total: 6.^[212]

Greece Another one case confirmed. Total: 4.^[213]

Estonia First confirmed case.^[214]

United States CDC FluView Week 21: Widespread influenza activity in five states, regional activity in 10.^[215]

Dominican Republic Nine more cases confirmed, for a total of 11 cases nationwide.^[216]

WHO As of 06:00 GMT, 62 countries have officially reported 17,410 cases of influenza A(H1N1) infection, including 115 deaths.^[217]

Bulgaria First confirmed case.^[218]

Bermuda First case confirmed.^[219]

Egypt First case confirmed.^[220]

Luxembourg First case confirmed.^[221]

Nicaragua First case confirmed.^[222]

WHO As of 06:00 GMT, 3 June 2009, 66 countries have officially reported 19,273 cases of influenza A(H1N1) infection, including 117 deaths.^[223]

Saudi Arabia First confirmed case.^[224]

Barbados First confirmed case.^[225]

Malaysia Three more cases confirmed. One of the patients is a 23-year-old student returned from the United States. Another two patients are German tourists who arrived in Singapore after having gone to Malaysia for holiday. Total: 5.^[226]

Trinidad and Tobago First confirmed case.^[227]

WHO As of 06:00 GMT, 69 countries have officially reported 21,940 cases of influenza A(H1N1) infection, including 125 deaths.^[228]

Australia 1006 cases confirmed.^[229]

Cayman Islands First case confirmed.^[230]

Dominican Republic First fatality, a 17-year-old pregnant girl. Total number of confirmed cases rises to 44.^[231]

Ukraine First confirmed case.

Malaysia One more case confirmed. Total: 7.^[232]

United States CDC FluView Week 22: Widespread influenza activity in eight states, regional activity in nine. "Approximately 89% of all influenza viruses being reported to CDC were novel influenza A (H1N1) viruses."^[233]

Chile Second death confirmed.

Martinique First case confirmed.^[234]

New Zealand Authorities have confirmed that a man traveling from North America has Influenza A(H1N1). Total: 14.^[235]

WHO As of 06:00 GMT, 73 countries have officially reported 25,288 cases of influenza A(H1N1) infection, including 139 deaths.^[236]

Dominica First confirmed case.^[237]

New Zealand Three more confirmed cases, two of which were from international flights. Total: 17.^[238]

WHO As of 06:00 GMT, 74 countries have officially reported 27,737 cases of influenza A(H1N1) infection, including 141 deaths.^[228]

Colombia First death confirmed.^[239]

French Polynesia First confirmed case in the islands.^[240]

Guatemala First death confirmed.^[241][242]

The WHO raises its Pandemic Alert Level to Phase 6, citing significant transmission of the virus.^{[243][244][245]}

Australia 1263 cases nationally, with more than 1000 cases in the State of Victoria alone.^[246]

British Virgin Islands First case confirmed in the islands.^[247]

Cuba Sixth case on the island, and that of the first citizen.^[248]

Palestinian Territories First case confirmed in the West Bank.^[247]

WHO As of 07:00 GMT, 12 June 2009, 74 countries have officially reported 29,669 cases of Influenza A (H1N1) infections, including 145 deaths.

Morocco First case confirmed.^[249]

Isle of Man First case confirmed.^[250]

Bolivia First two domestic infections. Total: 7.^[251]

Malaysia One more confirmed case. Total: 12.^[252]

United States Widespread influenza activity in eleven states, regional activity in six. "Over 98% of all subtyped influenza A viruses being reported to CDC were pandemic influenza A (H1N1) viruses."^[253]

Malaysia Five more cases of H1N1 confirmed. Total: 17.^[254]

United Kingdom First death confirmed.^[255]

Sri Lanka First confirmed case.^[256]

Monaco First confirmed case.^[257]

Malaysia Four more cases of H1N1 confirmed. One domestic infection confirmed. Total: 23.^[258]

Antigua and Barbuda First confirmed case.^[259]

Bangladesh First confirmed case.^[260]

Ethiopia First two cases confirmed.^[261]

Slovenia First confirmed case.^[262]

Philippines First death in Asia confirmed. H1N1 deaths now confirmed in 3 of 6 WHO regions.^[263]

Iraq First seven cases confirmed.^[264]

Japan 52 more cases confirmed. Total: 944.

Serbia First confirmed case.^[265]

United States CDC FluView Week 24: Widespread influenza activity in twelve states, regional activity in seven. "Over 99% of all subtyped influenza A viruses being reported to CDC were pandemic influenza A (H1N1) viruses."^[266]

United States CDC FluView Week 25: Widespread influenza activity in ten states, regional in 11 states.^[267]

Bosnia and Herzegovina First case confirmed.^[268]

Denmark First case of Oseltamivir (Tamiflu) resistance found. Confirmed by David Reddy, Roche's pandemic taskforce leader.^[269]

Kenya First confirmed case.^[270]

Mauritius First case confirmed.^[271]

Nepal First three confirmed cases.^[272]

South Africa South Africa National Health Department confirm community outbreak, with 7 new confirmed cases. The total of confirmed cases grew to 12640 within South Africa over the next few months.^{[citation needed]}

Guam First case confirmed.^[273]

Australia First confirmed death in NSW. National total: 10.^[274]

Japan Second case found with mutation resulting in Oseltamivir (Tamiflu) resistance.^[275]

United States CDC FluView Week 26: Widespread influenza activity in nine states, regional influenza activity in 12. "Over 97% of all subtyped influenza A viruses being reported to CDC were novel influenza A (H1N1) viruses."^[276]

Portugal First human-to-human transmission. Total: 38.^[277]

Syria First case confirmed.^[278]

Peru First two deaths confirmed.^[279]

WHO 429 deaths worldwide are reported.^[280]

Belize First five cases confirmed.^[281]

Tanzania First case confirmed.

United States CDC FluView Week 27: Widespread influenza activity in nine states, regional activity in 12. "Over 99% of all subtyped influenza A viruses being reported to CDC were novel influenza A (H1N1) viruses."^[282]

Colombia 6th death case confirmed out of 165 infected^[283]

Malaysia 39 more cases confirmed. Total: 710.

United Kingdom Another 2 deaths confirmed. Total Deaths: 17.

Brazil One more death confirmed. Total Deaths: 3.^[284]

Ecuador Third death confirmed. Total deaths: 3.^[285]

Brazil Fourth death confirmed.

Malaysia 32 more cases confirmed. Total: 804

New Zealand Two more deaths confirmed. Total deaths 9. Total confirmed cases: 1,984.

Singapore First flu-related death confirmed, that of a 49-year-old man with heart problems.^[286]

Sudan First two confirmed cases of H1N1 detected, from flights which had arrived from the U.K.^[287]

Hawaii First death, that of a sexagenarian with underlying health problems.^[288]

United States CDC FluView Week 28: Widespread influenza activity in seven states, regional activity in 13. "Over 99% of all subtyped influenza A viruses being reported to CDC were novel influenza A (H1N1) viruses."^[289]

Venezuela First death confirmed, that of an 11-year-old girl.^[290]

Singapore First death with H1N1 involvement confirmed, that of a 49-year-old male who also suffered from diabetes, hypertension and high cholesterol, from a heart attack caused by severe pneumonia.^[291]

Egypt First death confirmed.^[292]

Georgia First case confirmed.^[293]

Albania First case confirmed.^[294]

Guam First death confirmed.^[295]

Namibia First two H1N1 cases confirmed.^[296]

Canada The fourth case of mutation in the world from Tamiflu has been found in a 60-year-old man from Quebec, Canada.^[297]

Federated States of Micronesia First case confirmed, that of a 27-year-old male.^[298]

Northern Mariana Islands First two cases of H1N1 confirmed.^[299]

Hungary First death confirmed, that of a man with underlying heart and lung disease.^[300]

Tonga First death confirmed.^[301]

The WHO ceases the tracking of cumulative individual cases.^[302]

Arab League Health Ministers hold a summit after the death of a pilgrim who had returned from the Hajj. New regulations were promulgated for the Hajj: anyone younger than 12 or older than 65 or who have "chronic health problems" shall not be allowed to undertake the pilgrimage to Mecca.^[303]

Bhutan First case confirmed.^[304]

Malaysia First flu-related death confirmed, that of an obese 30-year-old male.^[305]

Canada Nova Scotia reports its first H1N1 death.^[306]

Cayman Islands First death reported, that of a man with underlying medical conditions.^[307]

Indonesia First H1N1 death confirmed, that of a 6-year-old girl suffering from severe pneumonia.^[308]

United States It is reported that thousands of Americans are being recruited for H1N1 vaccine testing at several research centers across the country.^[309] CDC FluView Week 29: Widespread influenza activity in four states, regional activity in eight. "Over 98% of all subtyped influenza A viruses being reported to CDC were novel influenza A (H1N1) viruses."^[310]

Norway An international 4H youth camp with 1,700 participants from fifteen nations is shut down after fifty Norwegian participants catch H1N1.^[311]

WHO 816 deaths worldwide are reported.^[312]

Germany Germany's federal infectious disease center, the Robert Koch Institute, states there were 3,810 confirmed cases of H1N1 in the country; nearly all of the cases are mild.^[313]

Israel First death confirmed, that of a 35-year-old man from Eilat.^[314]

Kosovo First case confirmed.^[315]

Saint Kitts and Nevis First death reported, that of a 28-year-old woman.^[316]

Saudi Arabia First death confirmed.^[317]

Japan Third case of Oseltamivir (Tamiflu) resistance.^[318]

Thailand In the first reported case of vertical transmission of A(H1N1), a baby is born infected.^[319]

Swaziland First case confirmed.^[320]

United Kingdom The NHS is not ready for a second wave of swine flu cases expected this autumn, a House of Lords committee has stated. It warned hospitals do not have enough intensive care beds to cope, and furthermore predicted that the recently established A(H1N1) flu helpline could be overwhelmed with calls.^[321]

United States The U.S. military wants to establish regional teams of military personnel to assist civilian authorities in the event of a significant outbreak of the H1N1 virus this fall, according to Defense Department officials.^[322]

Azerbaijan First two cases of A(H1N1) confirmed, those of people who had been on holiday in France and the U.K., respectively.^[323]

Belgium First death confirmed, that of a 34-year-old woman.^[324]

France First death confirmed, a 14-year-old girl in Brest.^[325]

Gabon First case confirmed.^[326]

Lebanon First death confirmed, that of a 30-year-old male.^[327]

Moldova First case confirmed.^[328]

Saudi Arabia Second H1N1 death confirmed, that a 28-year-old Indonesian woman.^[329]

Taiwan First death confirmed, that of a 39-year-old man.^[330]

WHO 1,154 deaths worldwide are reported.^[331]

France The cruise ship Voyager of the Seas, which had reported dozens of cases of H1N1 flu amongst its 5,000 passengers and crew, docks in France.^[332]

Australia First case of reverse zoonosis confirmed in a piggery in Dunedoo.^[333]

United States CDC FluView Week 30: Widespread influenza activity in four states, regional activity in 11. "Over 98% of all subtyped influenza A viruses being reported to CDC were novel influenza A (H1N1) viruses."^[334]

South Africa First confirmed death in South Africa. Total number of deaths at end of epidemic 93.^{[citation needed]}

India First death confirmed.^[335]

Netherlands First death confirmed, that of a 17-year-old male.^[336]

Solomon Islands First case confirmed.^[337]

WHO 1,462 deaths worldwide are reported.^[338]

United States CDC FluView Week 31: Widespread influenza activity in four states, regional activity in 10.^[339]

Costa Rica President Óscar Arias is confirmed to have swine flu, the first head of state known to have been infected.^[340]

WHO 1,799 deaths worldwide are reported.^[341]

Madagascar First case confirmed.^[342]

Democratic Republic of the Congo First H1N1 case confirmed.^[343]

United States CDC FluView Week 32: Widespread influenza activity in two states, regional activity in eight.^[344]

Malaysia Two more deaths confirmed. Total: 64 deaths.^[345]

Malta First death confirmed.^[345]

Malaysia Three more deaths confirmed. Total: 67 deaths.^[346]

Belarus First H1N1 case confirmed.^{[citation needed]}

Kuwait First death confirmed.^[347]

Malaysia One more death confirmed. Total: 68 deaths.^[348] The unusually high reported death rate, four times the global average,^[349] is investigated by the WHO.^[350]

Netherlands Second death confirmed, that of a 58-year-old male.^[336]

Chile H1N1 is found in turkeys on farms in Chile near the port city of Valparaiso in a unique zoonosis cluster.^[351]

Germany 13,740 A(H1N1) cases confirmed.^[352]

Oman First death confirmed.^[353]

United Arab Emirates First death confirmed.^[354]

United Kingdom First death confirmed in Northern Ireland, that of woman with underlying health conditions.^[355]

New Caledonia First death confirmed.^[356]

United States CDC FluView Week 33: Widespread influenza activity in two states, regional activity in 13. Activity appears to be increasing in the Southeast.^[357]

WHO At least 2,185 deaths worldwide are reported.^[358]

Greece First death confirmed.^[359]

Germany 14,325 H1N1 cases confirmed.^[360]

Kyrgyzstan First two cases confirmed, that of a husband and wife; the man had recently traveled to Dubai.^[361]

Malaysia One more death confirmed. Total: 69 deaths.^[362]

Malaysia One more death confirmed. Total: 70 deaths.^[363]

Angola First case confirmed.^[364]

Germany 14,940 H1N1 cases confirmed.^[365]

Iran First death confirmed^{[citation needed]}

Malaysia One more death confirmed. Total: 71 deaths.^[366]

Syria First death confirmed.^[367]

UN;Chile The United Nations issues a warning regarding the discovery of H1N1-infected turkeys on farms in Chile, an unusual case of zoonosis which raises concerns about possible increased genetic reassortment of the virus.^[368]

WHO Most countries in the Southern Hemisphere (represented by Chile, Argentina, New Zealand, and Australia) appear to have passed their peak of influenza activity and returned to baseline activity.^[358]

ECDC Based partially on data from the Southern Hemisphere, the ECDC forecasts a first wave of infections in autumn and winter which stresses hospitals in particular; it is noted, however, that "the overall interruption of essential services in (well-prepared) countries has been manageable".^[369]

Germany 15,567 H1N1 cases confirmed.^[370]

Bangladesh First death confirmed.^[371]

Brazil 602 H1N1 deaths confirmed, the highest number of any nation-state to date.^[372]

United States CDC FluView Week 34: Influenza activity, which had been largely stable or decreasing in prior weeks, increases in the U.S. "Six states and Puerto Rico reported geographically widespread influenza activity, 13 states reported regional influenza activity, 10 states and the District of Columbia reported local influenza activity, 19 states reported sporadic influenza activity, two states reported no influenza activity, and Guam and the U.S. Virgin Islands did not report." Furthermore, Region IV, i.e. the Southeast, reports increased out-patient ILI above its regional baseline.^[373]

WHO At least 2,837 deaths worldwide are reported.^[374]

Colombia President Álvaro Uribe is confirmed to have swine flu, the second Head of state known to have been infected.^[375]

Djibouti First seven cases confirmed.^[376]

United Arab Emirates Second death confirmed, that of a thirty-year-old Pakistani expatriate who died following Caesarian section.^[377]

Argentina The most H1N1 deaths per capita.^[378]

Bahrain First death confirmed, a South East Asian woman in her thirties with underyling medical conditions.^[377]

Sweden First death confirmed.^[379]

Macau First death confirmed.^[380]

Portugal 5,123 cases officially confirmed^[381]

Malaysia One more death confirmed. Total: 73 deaths.^[382]

Norway First death confirmed.^[383]

United States The CDC in its Morbidity and Mortality Weekly Report^[384] notes that 67% of thirty-six children who have died from H1N1 early in the epidemic had at least one serious chronic medical condition, with neurodevelopmental conditions such as developmental delay, epilepsy, and cerebral palsy being especially prominent.^[385] Roughly one in thirteen deaths have been of school-age children. More than 80% of the children who died were five or older, in contrast with the seasonal flu baseline of half or more of the influenza fatalities being four or younger.^[386]

Italy First death confirmed.^[387]

United States CDC FluView Week 35: Influenza increases in the U.S. with widespread influenza activity in 11 states and regional activity in 13; the proportion of outpatient visits for influenza-like illness (ILI) is above the national baseline, with four out of ten HHS Surveillance Regions reporting ILI above region-specific baselines. "97% of all subtyped influenza A viruses being reported to CDC were 2009 influenza A (H1N1) viruses."^[388]

WHO At least 3,205 deaths worldwide are reported.^[389]

Ecuador Ecuador's chief of presidential security, Col. John Merino, dies of H1N1 flu^[390] after twenty-eight days at Quito Military Hospital.^[391]

Faroe Islands First 44 cases confirmed.^[392]

Namibia First death confirmed, that of a 37-year-old businessman who had fallen ill in Angola.^[393]

Suriname First death confirmed.^[394]

Madagascar First death confirmed.^[395]

USA An outbreak is confirmed at the gaming convention PAX in Seattle, Washington.^{[396][397][398][399]}

Malawi First case confirmed.^[400]

Australia First case of Oseltamivir (Tamiflu) resistance found.^[401]

United States CDC FluView Week 36: Influenza activity continues to increase with widespread influenza activity in twenty-one states, regional influenza activity in nine. Seven of ten HHS Surveillance Regions report ILI activity above region-specific baselines. "99% of all subtyped influenza A viruses being reported to CDC were 2009 influenza A (H1N1) viruses."^[402]

WHO At least 3,486 deaths worldwide are reported.^[403]

Mozambique First death confirmed, that of a 29-year-old female with an unspecified chronic illness.^[404]

Malta Third death confirmed.^[405]

Netherlands The third and fourth deaths are confirmed, that of a 52-year-old man and an 85-year-old woman, respectively, both of whom had underlying medical conditions.^[406]

United Kingdom Health Minister Andy Burnham states that the second peak of swine flu has started as 5,000 people contracted the virus this week, compared to 3,000 the week before.^[405]

Martinique First death confirmed, that of an 18-month-old girl.^[407]

Malaysia One more death confirmed. Total: 77 deaths.^[408]

United States CDC FluView Week 37: Widespread influenza activity in twenty-six states, regional activity in 11. All of the HHS ILI regions report elevated levels of influenza activity above their region-specific baselines except for Region I (New England).^[409]

WHO Over 3,917 deaths worldwide are reported.^[410]

China A national vaccination campaign begins in China, making it the first country to issue the H1N1 vaccine.^[411]

United States The U.S. government orders a total of 251 million doses of H1N1 vaccine from manufacturers, up from the long-planned total of 195 million.^[412]

Portugal The first death confirmed, that of a Portuguese man living in France.^[413]

Germany First death confirmed, that of a 36-year-old woman who died of a so-called superinfection which included H1N1.^[414]

United States Forty-two schools are closed in eight states as the second wave of the pandemic begins in early autumn.^[415]

United States CDC FluView Week 38: Widespread influenza activity in twenty-seven states, regional activity in 18.^[416]

WHO At least 4,108 deaths worldwide are reported.^[417]

United States The second wave of the H1N1 pandemic begins to stress hospitals in the U.S. and prompts some school closures.^[415][418]

Cambodia First death confirmed, in Phnom Penh.^[419]

Ireland First case of reverse zoonosis in pigs.^[420]

Australia Mass vaccination drive begins, the second in the world.^[421]

Bulgaria First death confirmed.^[419]

China Sinovac Biotech Ltd., the first company worldwide to complete clinical trials for a vaccine, receives an order for an additional 3 million doses of H1N1 vaccine from the PRC government, making for a total of 6.3 million doses.^[422][423]

United States 46 states and Washington, D.C. begin ordering what becomes by the next day a cumulative total of 1,378,200 doses of the nasal-spray Live Attenuated Influenza Vaccine (LAIV)^[424] for H1N1.

United States CDC FluView Week 39: The proportion of deaths attributed to pneumonia and influenza (P&I) reaches the epidemic threshold with eight out of ten HHS ILI regions reporting region-specific ILI activity above region-specific baseline levels. Widespread influenza activity in thirty-seven states, regional activity in 11.^[425]

WHO At least 4,525 deaths worldwide are reported.^[426]

Tajikistan First case confirmed.^[426]

United States The CDC's 2009–10 influenza season officially begins.^[416][427]

United Nations Rich countries should make more vaccines available to poorer nations where the H1N1 virus is starting to hit, United Nations health officials said. They said increased readiness for swine flu was needed in developing countries with weaker medical systems and with large, young populations, who are most vulnerable to the disease. Some countries, such as the United States, Brazil and France, have agreed to make 10 percent of their national vaccine stockpile available to developing countries. Manufacturers have also donated about 150 million doses of vaccine.^[428]

China First death confirmed, in Lhasa, Tibet.^[429]

Tanzania First death confirmed.

Yemen Tamiflu resistance found.^[376]

Cuba First deaths confirmed, that of three pregnant women.^[430]

United States CDC FluView Week 40: The proportion of deaths attributed to pneumonia and influenza (P&I) is officially above the epidemic threshold. Moreover, for the first time all 10 HHS ILI regions reported ILI above region-specific baseline levels. Widespread influenza activity in forty-one states, and regional activity in eight, with only one state—Hawaii—reporting local influenza activity.^[431]

WHO At least 4,735 deaths worldwide are reported.^[432]

Norway first case of reverse zoonosis detected in Nord-Trøndelag.^[433]

Rwanda First cases confirmed.^[434]

São Tomé and Príncipe First cases confirmed.^[434]

Sweden Mass vaccination begins.^[435]

Vietnam Three cases of Tamiflu resistance (which developed during hospital treatment) are confirmed. The resistant strains were apparently not transmitted, and all three patients survived.^[436]

Mongolia First cases confirmed.^[437]

India Six more deaths confirmed. Total: 405 deaths.^[438]

Trinidad and Tobago First death confirmed.^[439]

United Kingdom The death toll passes 100. Total confirmed deaths: 106. The NHS confirms that second wave of swine flu has begun, with cases in Wales and Northern Ireland being especially high. The Minister of Health confirms that there were 27,000 cases in the last week in England alone, up from 14,000 the week before. The Minister of Health also announced that 415,000 H1N1 vaccinations shall take place on the week beginning 21 October, then 5,000,000 more vaccinations the week after. 20% of all hospitalized cases are now critical, up from 12% the week before. The government believes it can get 50,000,000 Britons vaccinated before Christmas.^[440]

United States An initial shortfall of swine flu vaccine is predicted shortly after the proportion of deaths attri