American college football season
The 2021 Mercer Bears football team represented Mercer University in the 2021 NCAA Division I FCS football season as a member of the Southern Conference (SoCon). The Bears were led by second-year head coach Drew Cronic and played their home games at Moye Complex in Macon, Georgia.
Date | Time | Opponent | Rank | Site | TV | Result | Attendance |
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| 7:00 p.m. | Point* | | | ESPN+ | W 69–0 | 8,727 |
September 11 | 4:00 p.m. | at No. 1 (FBS) Alabama* | | | SEC Network | L 14–48 | 95,396 |
September 25 | 2:00 p.m. | at Furman | | | ESPN+ | W 24–3 | 10,203 |
October 2 | 6:00 p.m. | Samford | | | ESPN+ | W 45–42 | 11,137 |
October 9 | 3:30 p.m. | at Western Carolina | | | ESPN+ | W 34–24 | 11,123 |
October 16 | 4:00 p.m. | VMI | | | ESPN+ | L 7–45 | 7,227 |
October 23 | 6:00 p.m. | Wofford | | | ESPN+/Nexstar | W 45–14 | 7,224 |
October 30 | 2:00 p.m. | at The Citadel | | | ESPN+ | W 34–7 | 8,438 |
November 13 | 3:00 p.m. | No. 22т Chattanooga | | | ESPN+ | W 10–6 | 8,527 |
November 20 | 1:00 p.m. | at No. 8 East Tennessee State | No. 21 | | ESPN3 | L 35–38 | 10,594 |
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