3-Hydroxyoctanoic acid
![]() | |
Names | |
---|---|
Preferred IUPAC name 3-Hydroxyoctanoic acid | |
Other names 3-Hydroxycaprylic acid; β-Hydroxyoctanoic acid | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChemSpider | |
MeSH | C101940 |
PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
| |
| |
Properties | |
C8H16O3 | |
Molar mass | 160.213 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
3-Hydroxyoctanoic acid is a beta-hydroxy acid that is naturally produced in humans, other animals, and plants.
3-Hydroxyoctanoic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 3 (HCA3), a G protein-coupled receptor protein which is encoded by the human gene HCAR3.[1][2] In plants, signalling chemical emitted by the orchid Cymbidium floribundum and recognized by Japanese honeybees (Apis cerana japonica).[3]
References
[edit]- ^ Offermanns, S; Colletti, S. L; Lovenberg, T. W; Semple, G; Wise, A; Ijzerman, A. P (June 2011). "International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)". Pharmacological Reviews. 63 (2): 269–90. doi:10.1124/pr.110.003301. PMID 21454438.
- ^ Offermanns, S.; Colletti, S. L.; IJzerman, A. P.; Lovenberg, T. W.; Semple, G.; Wise, A.; Waters, M. G.; CGTP Collaborators. "Hydroxycarboxylic acid receptors". IUPHAR/BPS Guide to Pharmacology. International Union of Basic and Clinical Pharmacology. Retrieved 13 July 2018.
- ^ Sugahara, M; Izutsu, K; Nishimura, Y; Sakamoto, F (2013). "Oriental orchid (Cymbidium floribundum) attracts the Japanese honeybee (Apis cerana japonica) with a mixture of 3-hydroxyoctanoic acid and 10-hydroxy- (E)-2-decenoic acid". Zoological Science. 30 (2): 99–104. doi:10.2108/zsj.30.99. PMID 23387843. S2CID 45520680.