4-Fluoro-L-threonine
Names | |
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IUPAC name 4-Fluoro-L-threonine | |
Systematic IUPAC name (2S,3S)-2-Amino-4-fluoro-3-hydroxybutanoic acid | |
Other names 4-Fluorothreonine | |
Identifiers | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
CompTox Dashboard (EPA) | |
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Properties | |
C4H8FNO3 | |
Molar mass | 137.110 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
4-Fluoro-l-threonine is an antibacterial produced by Streptomyces cattleya. It is formed by the fluorothreonine transaldolase catalysed transfer of fluoroacetaldehyde onto threonine.[1]
References
[edit]- ^ Murphy CD, O'Hagan D, Schaffrath C (2001). "Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews". Angew. Chem. Int. Ed. Engl. 40 (23): 4479–4481. doi:10.1002/1521-3773(20011203)40:23<4479::AID-ANIE4479>3.0.CO;2-1. PMID 12404452.