8-oxoguanine deaminase

8-oxoguanine deaminase
Identifiers
EC no.3.5.4.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
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NCBIproteins

8-oxoguanine deaminase (EC 3.5.4.32, 8-OGD) is an enzyme with systematic name 8-oxoguanine aminohydrolase.[1] This enzyme catalyses the following chemical reaction

8-oxoguanine + H2O urate + NH3

Zn2+ is bound in the active site.

References

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  1. ^ Hall RS, Fedorov AA, Marti-Arbona R, Fedorov EV, Kolb P, Sauder JM, Burley SK, Shoichet BK, Almo SC, Raushel FM (February 2010). "The hunt for 8-oxoguanine deaminase". Journal of the American Chemical Society. 132 (6): 1762–3. doi:10.1021/ja909817d. PMC 2820149. PMID 20088583.
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