Junction number | Destinations | Notes |
| A 6a north - Villejuif; Paris; Arcueil (E 5 north; E 15 north; E 50 east) | northbound exit and southbound entrance |
| A 6b north - Lille; Metz; Nancy; Rungis; Aéroport Orly; Créteil | northbound exit (Rue de Kuhlman) and southbound entrance |
| Massy; Longjumeau; Antony-Z.A. (N 20 north) | no northbound exit; N 20 joins southbound |
| N 20 south - Étampes; Orléans; La Ville-du-Bois; Linas; Montlhéry; Longjumeau | no southbound entrance; N 20 leaves southbound |
| A126 to A 6 south - Évry; Lyon; Chilly-Mazarin |
| N188 - Palaiseau; Antony; Massy; Villebon-sur-Yvette |
| N444 - Versailles; Igny; Bièvres; Cité scientifique | southbound exit and northbound entrance |
| Gare de Massy-Palaiseau | northbound exit and southbound entrance |
| N 188 - Orsay; Bures | southbound exit and northbound entrance |
| Chartres; Les Ulis; Orsay; Z.A. de Courtabœuf | southbound exit and northbound entrance |
| N118 - Les Ulis; Rouen; Versailles; Boulogne-Billancourt; Paris-Porte de Saint-Cloud; Z.A. de Courtabœuf | northbound exit and southbound entrance |
| N 104 - Lyon; Metz; Nancy; Évry; Orléans via N 20; Linas; Montlhéry; Arpajon |
10 | Dourdan; Limours; Saint-Arnoult-en-Yvelines |
Péage de Saint-Arnoult |
| A11 west - Ablis; Chartres; Le Mans; Rennes (E 50 west) | southbound exit and northbound entrance; E 50 joins northbound and leaves southbound |
11 | Étampes; Rambouillet; Allainville (N 191) |
12 | Chartres; Janville; Châteaudun (N 254) |
13 | Artenay (N154) |
14 | E60 east - Orléans-Nord; Montargis; Fontainebleau; Saran; Centre Routier; Fleury-les-Aubrais (A 701 east) | E60 joins southbound and leaves northbound |
| A71 south - Orléans-Centre; Orléans-la Source; Vierzon; Bourges; Limoges; Clermont-Ferrand (E9 south) |
15 | Meung-sur-Loire; Beaugency |
16 | Mer; Chambord; Beaugency (N 152) |
17 | Blois; Vendôme; La Chaussée-Saint-Victor (N 252) |
18 | Angers; Château-Renault; Amboise |
Péage de Monnaie |
| A 28 north - Rouen; Le Mans |
19 | Tours-Nord; Chartres; Le Mans; Angers; Laval; Aéroport Saint-Symphorien; Z.I. Tours-Nord (N 10; E 60 west) | E60 joins northbound and leaves southbound |
20 | Montlouis; Blois via Route nationale; Le Mans; Laval; Tours-Nord; Vouvray; Tours Val de Loire Airport (N 521) |
21 | Tours-Centre; Montlouis; Saint-Pierre-des-Corps; Amboise |
22 | Vierzon; Tours-Sud; Saint-Avertin (N 76; E 604) | southbound exit and northbound entrance |
23 | Châteauroux; Montbazon; Chambray; Loches (N 10; N 143) | southbound exit and northbound entrance |
23 | Tours-Sud; Saint-Avertin; Chambray-Centre (N 10) | northbound exit and southbound entrance |
24 | Saumur; Chambray-Sud; Joué-lès-Tours; Montbazon; Chinon (N 585) |
24.1 | Monts; Sorigny; Montbazon; Z.A. Isoparc |
Péage de Sorigny |
25 | Chinon; Sainte-Maure-de-Touraine; Loches |
26 | Châtellerault-Centre; Châtellerault-Nord; La Roche-Posay |
27 | Châtellerault-Sud; Châtellerault-Centre; Naintré (N 10) |
28 | Futuroscope; Jaunay-Clan; Chasseneuil-du-Poitou |
29 | Limoges; Poitiers-Centre; Parthenay; Saumur; Angers; Poitiers-Nord (N 147; E 62) |
30 | Angoulême; Poitiers-Sud; Poitiers-Centre; Vivonne; Lusignan (N 10) |
31 | Saint-Maixent-l'École; Lusignan (N 11) |
| A83 north - Angers; Nantes; La Roche-sur-Yon; Niort-Centre; Saint-Maixent-l'École |
32 | Limoges; Angoulême; Melle; Niort-Est; Niort-Centre; Marais Poitevin |
33 | Rochefort; La Rochelle; Surgères; Niort-Sud; Marais Poitevin (N 150; N 248; E 601) |
34 | Cognac; Surgères; Aulnay; Saint-Jean-d'Angély |
| A837 north - La Rochelle; Rochefort (E 602 north) | northbound exit and southbound entrance |
35 | E603 - Angoulême; Ile d'Oléron; Royan; Saintes (N 137) |
36 | Jonzac; Cognac; Pons |
37 | Montendre; Royan; Jonzac; Mirambeau |
38 | Blaye; Montendre; Saint-Ciers-sur-Gironde |
Péage de Virsac |
39a | Libourne; Saint-André-de-Cubzac; Bourg; Coutras; Saint-Antoine; Z.A. la Garosse (N 10) |
39b | Angoulême; Barbezieux (N 10 north; E 606 north) | northbound exit and southbound entrance |
40a | Royan via Route nationale; Saintes via RN; Blaye (N 137; E 606) | northbound exit and southbound entrance |
40b | Libourne; Saint-André-de-Cubzac; Bourg | northbound exit and southbound entrance |
41 | Ambès; Z.I. Bassens; Zone portuaire |
42 | Ambarès; Saint-Loubès (N 10 north) |
43 | Ambarès; Sainte-Eulalie; Carbon-Blanc |
44 | Carbon-Blanc; Bassens | southbound exit only |
45 | Lormont | southbound exit and northbound entrance |
1 | N 230 - Toulouse; Bayonne; Bassin d'Arcachon; Bordeaux; Périgueux | southbound exit and northbound entrance |
| A630 - Mérignac (E 5 south) | southbound exit and northbound entrance |