CagZ

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

CagZ
CagZ
	crystal structure of cag-z from helicobacter pylori
Identifiers
Symbol	CagZ
Pfam	PF09053
InterPro	IPR015139
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

In molecular biology, CagZ is a protein produced by Helicobacter pylori (Campylobacter pylori). It is a 23 kDa protein consisting of a single compact L-shaped domain, composed of seven alpha-helices that run antiparallel to each other. 70% of the amino acids are in alpha-helix conformation and no beta-sheet is present. CagZ is essential for the translocation of the pathogenic protein CagA into host cells.^[1]

References

^ Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G (July 2004). "Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system". J. Mol. Biol. 340 (4): 881–9. doi:10.1016/j.jmb.2004.05.016. PMID 15223328.

This article incorporates text from the public domain Pfam and InterPro: IPR015139

[pmid15223328-1] Cendron L, Seydel A, Angelini A, Battistutta R, Zanotti G (July 2004). "Crystal structure of CagZ, a protein from the Helicobacter pylori pathogenicity island that encodes for a type IV secretion system". J. Mol. Biol. 340 (4): 881–9. doi:10.1016/j.jmb.2004.05.016. PMID 15223328.

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