Chinese VX

Chinese VX^[1]
Names
	Preferred IUPAC name O-Butyl S-[2-(diethylamino)ethyl] methylphosphonothioate
	Other names CVX; EA-6043
Identifiers
CAS Number	468712-10-9 ;
3D model (JSmol)	Interactive image;
ChemSpider	486553;
PubChem CID	559704;
CompTox Dashboard (EPA)	DTXSID001336412 ;
	InChI InChI=1S/C11H26NO2PS/c1-5-8-10-14-15(4,13)16-11-9-12(6-2)7-3/h5-11H2,1-4H3 Key: BTVFLPKWKJBKNN-UHFFFAOYSA-N;
	SMILES CCCCOP(=O)(C)SCCN(CC)CC;
Properties
Chemical formula	C11H26NO2PS
Molar mass	267.37 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chinese VX (CVX), also known as EA-6043, is an organophosphate nerve agent of the V-series. It is a structural isomer of both VX and Russian VX.^[2]^[3]

References

^ Antonijevic, B.; Stojiljkovic, M. P. (1 March 2007). "Unequal Efficacy of Pyridinium Oximes in Acute Organophosphate Poisoning". Clinical Medicine & Research. 5 (1): 71–82. doi:10.3121/cmr.2007.701. PMC 1855336. PMID 17456837.
^ Wandhammer, Marielle; Carletti, Eugénie; Van der Schans, Marcel; Gillon, Emilie; Nicolet, Yvain; Masson, Patrick; Goeldner, Maurice; Noort, Daan; Nachon, Florian (13 May 2011). "Structural Study of the Complex Stereoselectivity of Human Butyrylcholinesterase for the Neurotoxic V-agents". Journal of Biological Chemistry. 286 (19): 16783–16789. doi:10.1074/jbc.M110.209569. PMC 3089521. PMID 21454498.
^ Patrice L. Abercrombie-Thomas, Ann Brozena, James H. Buchanan, Michael W. Ellzy, Frederic J. Berg, Kenneth B. Sumpter, Phillip G. Wilcox, David E. Tevault, Leonard C. Buettner, Ian J. Pardoe, Barry R. Williams, Melissa S. Hulet, Erik D. Emmons, Thermophysical Properties and Spectral Characterization of EA 6043 (PDF), Belcamp/Gunpowder: Department of the Army, Edgewood Arsenal Research Laboratories, archived (PDF) from the original on October 23, 2019, retrieved 2020-02-07{{citation}}: CS1 maint: multiple names: authors list (link)

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[1] Antonijevic, B.; Stojiljkovic, M. P. (1 March 2007). "Unequal Efficacy of Pyridinium Oximes in Acute Organophosphate Poisoning". Clinical Medicine & Research. 5 (1): 71–82. doi:10.3121/cmr.2007.701. PMC 1855336. PMID 17456837.

[2] Wandhammer, Marielle; Carletti, Eugénie; Van der Schans, Marcel; Gillon, Emilie; Nicolet, Yvain; Masson, Patrick; Goeldner, Maurice; Noort, Daan; Nachon, Florian (13 May 2011). "Structural Study of the Complex Stereoselectivity of Human Butyrylcholinesterase for the Neurotoxic V-agents". Journal of Biological Chemistry. 286 (19): 16783–16789. doi:10.1074/jbc.M110.209569. PMC 3089521. PMID 21454498.

[ECBC-TR-1269-3] Patrice L. Abercrombie-Thomas, Ann Brozena, James H. Buchanan, Michael W. Ellzy, Frederic J. Berg, Kenneth B. Sumpter, Phillip G. Wilcox, David E. Tevault, Leonard C. Buettner, Ian J. Pardoe, Barry R. Williams, Melissa S. Hulet, Erik D. Emmons, Thermophysical Properties and Spectral Characterization of EA 6043 (PDF), Belcamp/Gunpowder: Department of the Army, Edgewood Arsenal Research Laboratories, archived (PDF) from the original on October 23, 2019, retrieved 2020-02-07{{citation}}: CS1 maint: multiple names: authors list (link)

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v t e Neurotoxins
Animal toxins	Batrachotoxin Bestoxin Birtoxin Bungarotoxin Charybdotoxin Conotoxin Fasciculin Huwentoxin Poneratoxin Saxitoxin Tetrodotoxin Vanillotoxin Spooky toxin (SsTx) Epibatidine Zetekitoxin AB Dendrotoxin
Bacterial	Botulinum toxin Tetanospasmin
Cyanotoxins	Anatoxin-a Guanitoxin BMAA Saxitoxin
Plant toxins	Aconitine Bicuculline Penitrem A Picrotoxin Strychnine Tutin Rotenone Ginkgotoxin Cicutoxin Oenanthotoxin Thujone Volkensin Veratridine
Mycotoxins	Ibotenic acid Muscarine Muscimol
Pesticides	Fenpropathrin Tetramethylenedisulfotetramine Bromethalin Crimidine Methamidophos Endosulfan Fipronil Phenylsilatrane Chlorophenylsilatrane Sulfuryl fluoride Mipafox Schradan Dimefox
Nerve agents	Cyclosarin EA-3148 Novichok agent Sarin Soman Tabun VE VG VM VP VR VX GV EA-3990 EA-4056 T-1123 Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide) Fluorotabun Chinese VX EA-2192
Bicyclic phosphates	TBPS TBPO IPTBO
Cholinergic neurotoxins	Acetylcholine mustard Catecholine Choline mustard Ethylcholine mustard Hemicholinium mustard
Psychoactive drugs	Alcohol Nitrous oxide
Other	Dimethylcadmium Dimethylmercury Toxopyrimidine IDPN Tetraethyllead

Names

Preferred IUPAC name O-Butyl S-[2-(diethylamino)ethyl] methylphosphonothioate
Other names CVX EA-6043
Identifiers
CAS Number	468712-10-9^Y
3D model (JSmol)	Interactive image
ChemSpider	486553
PubChem CID	559704
CompTox Dashboard (EPA)	DTXSID001336412
InChI InChI=1S/C11H26NO2PS/c1-5-8-10-14-15(4,13)16-11-9-12(6-2)7-3/h5-11H2,1-4H3 Key: BTVFLPKWKJBKNN-UHFFFAOYSA-N
SMILES CCCCOP(=O)(C)SCCN(CC)CC
Properties
Chemical formula	C₁₁H₂₆NO₂PS
Molar mass	267.37 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Chinese VX

See also

References