DENND1A

DENND1A
Identifiers
Aliases	DENND1A, FAM31A, KIAA1608, DENN domain containing 1A
External IDs	OMIM: 613633; MGI: 2442794; HomoloGene: 17141; GeneCards: DENND1A; OMA:DENND1A - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	123,930,152 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	38,177,402 bp
RNA expression pattern
	Top expressed in
	monocyte; ; bone marrow cells; ; ventricular zone; ; mucosa of ileum; ; granulocyte; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; prefrontal cortex; ; blood;
	Top expressed in
	neural layer of retina; ; zygote; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; secondary oocyte; ; muscle of thigh; ; right kidney; ; spermatocyte; ; spermatid;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity; SH3 domain binding; lipid binding; phosphatidylinositol phosphate binding; phosphatidylinositol-3-phosphate binding;
Cellular component	membrane; plasma membrane; synapse; cell junction; soma; dendrite; clathrin-coated vesicle membrane; presynaptic membrane; cytoplasmic vesicle; clathrin-coated vesicle; nucleoplasm; cytosol; intracellular membrane-bounded organelle;
Biological process	endocytosis; regulation of Rab protein signal transduction; synaptic vesicle endocytosis; protein transport; positive regulation of GTPase activity; endocytic recycling;
	Sources:Amigo / QuickGO
Orthologs
	57706
	227801
	ENSG00000119522
	ENSMUSG00000035392
	Q8TEH3
	Q8K382
NM_020946; NM_024820; NM_001352964; NM_001352965; NM_001352966;
	NM_001352967; NM_001352968; NM_001393654; NM_001400446; NM_001400449
	NM_146122; NM_001362973; NM_001362977; NM_001362978
NP_065997; NP_079096; NP_001339893; NP_001339894; NP_001339895;
	NP_001339896; NP_001339897
	NP_666234; NP_001349902; NP_001349906; NP_001349907
	Wikidata
View/Edit Human	View/Edit Mouse

DENN domain-containing protein 1A is a protein that in humans is encoded by the DENND1A gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119522 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035392 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (Dec 2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.
^ "Entrez Gene: DENND1A DENN/MADD domain containing 1A".

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119522 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035392 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10997877-5] Nagase T, Kikuno R, Nakayama M, Hirosawa M, Ohara O (Dec 2000). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (4): 273–81. doi:10.1093/dnares/7.4.271. PMID 10997877.

[entrez-6] "Entrez Gene: DENND1A DENN/MADD domain containing 1A".

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DENND1A

References

Further reading