Daniel W. Nebert

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Daniel W. Nebert
Nebert in 2004
Born	Portland, Oregon
Nationality	American
Alma mater	Wesleyan University (BA) University of Oregon Medical School (MS, MD)
Known for	Discovery of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS), aryl hydrocarbon receptor (AHR) Standardizing gene nomenclature system, based on evolutionary divergence Discovery of the SLC39A8 gene encoding ZIP8 transporter of divalent cations
Spouse	Lucia Fung Jorge
Children	6
Scientific career
Fields	Biomedical sciences, medicine
Institutions	National Institutes of Health University of Cincinnati College of Medicine Cincinnati Children's Hospital Medical Center

Daniel Walter Nebert is an American physician-scientist. He is a professor emeritus at the University of Cincinnati College of Medicine. His research has revolved around the central theme of gene–environment interactions.

Nebert completed a BA degree at Wesleyan University in 1960.^[1] He went on to the five-year program at the University of Oregon Medical School; he completed a MS in biophysics and an MD in 1964.^[1] Nebert had a pediatric internship and residency at the University of California, Los Angeles Health Sciences Center from 1964 to 1966.^[1] He was a postdoctoral fellow at the National Cancer Institute from 1966 to 1968.^[1]

Nebert moved to the NICHD in 1968. He remained there until 1989, and served as section head and the chief of the Laboratory of Developmental Pharmacology.^[1]

Nebert then moved to the University of Cincinnati Medical Center in December 1989, where he was hired as a professor of environmental health.^[1][2] He also had an adjunct professor title in the Human Genetics Division, Department of Pediatrics and Molecular & Developmental Biology at Cincinnati Children's Hospital Medical Center beginning in 1991.^[3] He remained at the University of Cincinnati until retiring as a professor emeritus in 2013.^[1][2]

Nebert has published more than 670 papers in several scientific fields. In January 2025, Nebert's Google Scholar h-index was 140 with more than 82,500 citations.^[4]

Nebert was elected a Fellow of the American Association for the Advancement of Science in 1994, as a member of the medical sciences section.^[5][6]

• Nebert DW, Gonzalez FJ. P450 genes: structure, evolution, and regulation. Annu Rev Biochem. 1987;56:945-93. PMID: 3304150
• Zhang G, Nebert DW. Personalized medicine: Genetic risk prediction of drug response. Pharmacol Ther. 2017 Jul;175:75-90. PMID: 28213088
• Nebert DW. Aryl hydrocarbon receptor (AHR): "pioneer member" of the basic-helix/loop/helix per-Arnt-sim (bHLH/PAS) family of "sensors" of foreign and endogenous signals. Prog Lipid Res. 2017 Jul;67:38-57. PMID: 28606467
• Nebert DW, Liu Z. SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside. Hum Genomics. 2019 Sep 14;13(Suppl 1):51. PMID: 31521203

• Daniel W. Nebert publications indexed by Google Scholar