Etymemazine
Chemical compound
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Other names | Ethylisobutrazine |
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Formula | C20H26N2S |
Molar mass | 326.50 g·mol−1 |
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Etymemazine is an antipsychotic, antihistamine and anticholinergic drug of the phenothiazine chemical class, structurally related to cyamemazine and methotrimeprazine.[1]
Synthesis
[edit]Etymemazine can be synthesized by SN2 alkylation of 2-ethylphenothiazine (1) with 1-dimethylamino-2-methyl-3-chloropropane (2) using sodamide as a base.[2][3]
References
[edit]- ^ Milne GW (2002). "Etymemazine". Drugs: Synonyms and Properties (2nd ed.). Aldershot, Hampshire, England: Ashgate. p. 3945. ISBN 978-0-566-08491-1.
- ^ GB 789703 (1958 to Rhone Poulenc Sa).
- ^ Robert Michel Jacob, et al. U.S. patent 2,837,518 (1956 to Rhone Poulenc Sa)
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Antidepressants (Tricyclic antidepressants (TCAs)) |
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Antihistamines |
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Antipsychotics |
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