FBP1

FBP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFBP1, FBP, fructose-bisphosphatase 1
External IDsOMIM: 611570; MGI: 95492; HomoloGene: 55467; GeneCards: FBP1; OMA:FBP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000507
NM_001127628

NM_019395

RefSeq (protein)

NP_000498
NP_001121100

NP_062268

Location (UCSC)Chr 9: 94.6 – 94.64 MbChr 13: 63.01 – 63.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Fructose-1,6-bisphosphatase 1 is a protein that in humans is encoded by the FBP1 gene.[5]

Function

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Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165140Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000069805Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: Fructose-1,6-bisphosphatase 1". Retrieved 2014-04-19.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.