English: A: An individual cell migrating over 10 h through an EP bridge that connects EP islands (not a connection between only two cells). The cell expanded the elastic structure of the EP bridge, which returned to original size after the cell passed (0–6 h). The migrating cell exited the EP bridge through an elastic sheath and migrated into the EP island (7–10 h). EP bridge length remained relatively stable over 31 h as ECs grew underneath the bridge. The EP bridge measured 623 µm at 0 h and 562 µm at 31 h. B: Lysosome (red) and nucleus (blue) staining in EPs/ECs show nuclei co-localized with lysosomes in an EP bridge connecting two EP islands. C–D: F-actin (red), Golgi marker (green), and nucleus (blue) immunostaining show co-localization of nuclei and Golgi suggesting an individual cell expanded the EP bridge structure (C-Ci), while multiple cells were within another EP bridge (D). Scale bars: (A 0 h and 31 h, B, C, D), 50 µm; (A subpanels, Ci), 10 µm.