H2AFV

H2AZ2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesH2AZ2, H2A.Z-2, H2AV, H2A histone family member V, H2A.Z variant histone 2, H2AFV
External IDsMGI: 1924855; HomoloGene: 83271; GeneCards: H2AZ2; OMA:H2AZ2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_201517
NM_012412
NM_138635
NM_201436
NM_201516

NM_029938
NM_001347064

RefSeq (protein)

NP_036544
NP_619541
NP_958844
NP_958924
NP_958925

NP_001333993
NP_084214

Location (UCSC)Chr 7: 44.83 – 44.85 MbChr 11: 6.38 – 6.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Histone H2A.V is a protein that in humans is encoded by the H2AFV gene.[5]

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. Several transcripts have been identified for this gene.[5]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105968Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041126Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: H2AFV H2A histone family, member V".

Further reading

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[edit]
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Histone H2A.V