KIF1B

KIF1B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIF1B, CMT2, CMT2A, CMT2A1, HMSNII, KLP, NBLST1, kinesin family member 1B
External IDsOMIM: 605995; MGI: 108426; HomoloGene: 99835; GeneCards: KIF1B; OMA:KIF1B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_183416
NM_015074
NM_001365951
NM_001365952
NM_001365953

NM_001290995
NM_008441
NM_207682

RefSeq (protein)

NP_055889
NP_904325
NP_001352880
NP_001352881
NP_001352882

NP_001277924
NP_032467
NP_997565

Location (UCSC)Chr 1: 10.21 – 10.38 MbChr 4: 149.26 – 149.39 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin-like protein KIF1B is a protein that in humans is encoded by the KIF1B gene.[5][6][7]

Clinical significance

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It is associated with Charcot–Marie–Tooth disease, type 2A1.[7]

Interactions

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KIF1B has been shown to interact with GIPC1.[8]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000054523Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063077Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T, Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N (June 2001). "Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta". Cell. 105 (5): 587–97. doi:10.1016/S0092-8674(01)00363-4. PMID 11389829. S2CID 17303998.
  6. ^ Nagai M, Ichimiya S, Ozaki T, Seki N, Mihara M, Furuta S, Ohira M, Tomioka N, Nomura N, Sakiyama S, Kubo O, Takakura K, Hori T, Nakagawara A (May 2000). "Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2". Int J Oncol. 16 (5): 907–16. doi:10.3892/ijo.16.5.907. PMID 10762626.
  7. ^ a b "Entrez Gene: KIF1B kinesin family member 1B".
  8. ^ Bunn RC, Jensen M A, Reed B C (April 1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the Cytoskeleton". Mol. Biol. Cell. 10 (4): 819–32. doi:10.1091/mbc.10.4.819. ISSN 1059-1524. PMC 25204. PMID 10198040.

Further reading

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