Mastermind-like 3 (drosophila)

MAML3
Identifiers
Aliases	MAML3, CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3, Mastermind-like 3, mastermind like transcriptional coactivator 3, mam-3
External IDs	OMIM: 608991; MGI: 2389461; HomoloGene: 41284; GeneCards: MAML3; OMA:MAML3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	140,154,184 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	52,012,497 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; corpus epididymis; ; gingival epithelium; ; skin of hip; ; tail of epididymis; ; parotid gland; ; visceral pleura; ; sural nerve; ; parietal pleura; ; caput epididymis;
	Top expressed in
	paraxial mesoderm; ; tail of embryo; ; ureter; ; genital tubercle; ; female urethra; ; placenta; ; male urethra; ; stroma of kidney; ; ventricular zone; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	transcription coactivator activity;
Cellular component	nucleus; nucleoplasm; nuclear speck;
Biological process	Notch signaling pathway; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; positive regulation of transcription of Notch receptor target; positive regulation of Notch signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	55534
	433586
	ENSG00000196782
	ENSMUSG00000061143
	Q96JK9
	n/a
	NM_018717
	NM_001004176
	NP_061187
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Mastermind-like 3 (Drosophila) is a protein that in humans is encoded by the MAML3 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196782 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061143 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Mastermind-like 3 (Drosophila)".

Margolis RL, Abraham MR, Gatchell SB, Li SH, Kidwai AS, Breschel TS, Stine OC, Callahan C, McInnis MG, Ross CA (July 1997). "cDNAs with long CAG trinucleotide repeats from human brain". Human Genetics. 100 (1): 114–22. doi:10.1007/s004390050476. PMID 9225980. S2CID 25999127.
Lin SE, Oyama T, Nagase T, Harigaya K, Kitagawa M (December 2002). "Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling". The Journal of Biological Chemistry. 277 (52): 50612–20. doi:10.1074/jbc.M209529200. PMID 12386158.
Hu Z, Shi Y, Mo X, Xu J, Zhao B, Lin Y, Yang S, Xu Z, Dai J, Pan S, Da M, Wang X, Qian B, Wen Y, Wen J, Xing J, Guo X, Xia Y, Ma H, Jin G, Yu S, Liu J, Zhou Z, Wang X, Chen Y, Sha J, Shen H (July 2013). "A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations". Nature Genetics. 45 (7): 818–21. doi:10.1038/ng.2636. PMID 23708190. S2CID 7904277.
Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ (February 2003). "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway". Nature Genetics. 33 (2): 208–13. doi:10.1038/ng1083. PMID 12539049. S2CID 23417795.
Wu L, Sun T, Kobayashi K, Gao P, Griffin JD (November 2002). "Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors". Molecular and Cellular Biology. 22 (21): 7688–700. doi:10.1128/MCB.22.21.7688-7700.2002. PMC 135662. PMID 12370315.

This article on a gene on human chromosome 4 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196782 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061143 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Mastermind-like 3 (Drosophila)".

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Mastermind-like 3 (drosophila)

References

Further reading