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DeutschMandelamide amidase
| mandelamide amidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.5.1.86 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction
- (R)-mandelamide + H2O (R)-mandelate + NH3
Thus, the two substrates of this enzyme are (R)-mandelamide and H2O, whereas its two products are (R)-mandelate and NH3.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.
References
[edit]- Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(−)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol. 57 (10): 3028–32. PMC 183915. PMID 1660699.
