Mandelamide amidase

mandelamide amidase
Identifiers
EC no.3.5.1.86
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction

(R)-mandelamide + H2O (R)-mandelate + NH3

Thus, the two substrates of this enzyme are (R)-mandelamide and H2O, whereas its two products are (R)-mandelate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.

References

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  • Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(−)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol. 57 (10): 3028–32. PMC 183915. PMID 1660699.