Protein-coding gene in the species Homo sapiens
NF-kappa-B-repressing factor is a protein that in humans is encoded by the NKRF gene .[ 5] [ 6]
This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes.
The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm .[ 6]
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