POPDC3

POPDC3
Identifiers
Aliases	POPDC3, POP3, bA355M14.1, popeye domain containing 3, LGMDR26
External IDs	OMIM: 605824; MGI: 1930153; HomoloGene: 32540; GeneCards: POPDC3; OMA:POPDC3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	105,180,014 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	45,194,548 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; muscle of thigh; ; vastus lateralis muscle; ; thoracic diaphragm; ; gastrocnemius muscle; ; Skeletal muscle tissue of biceps brachii; ; glutes; ; deltoid muscle; ; triceps brachii muscle;
	Top expressed in
	triceps brachii muscle; ; temporal muscle; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; gastrocnemius muscle; ; digastric muscle; ; ankle; ; medial head of gastrocnemius muscle; ; soleus muscle; ; lumbar spinal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	cAMP binding; nucleotide binding; molecular function;
Cellular component	membrane; integral component of membrane; sarcolemma;
Biological process	biological process; regulation of membrane potential; heart development; skeletal muscle tissue development; striated muscle cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	64208
	78977
	ENSG00000132429
	ENSMUSG00000019848
	Q9HBV1
	Q9ES81
	NM_022361
	NM_024286
	NP_071756
	NP_077248
	Wikidata
View/Edit Human	View/Edit Mouse

Popeye domain-containing protein 3 is a protein that in humans is encoded by the POPDC3 gene.^[5]^[6]

Function

This gene encodes a member of the POP family of proteins which contain three putative transmembrane domains. This membrane associated protein is predominantly expressed in skeletal and cardiac muscle, and may have an important function in these tissues.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132429 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019848 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: popeye domain containing 3".
^ Andrée B, Hillemann T, Kessler-Icekson G, Schmitt-John T, Jockusch H, Arnold HH, Brand T (July 2000). "Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart". Dev. Biol. 223 (2): 371–82. doi:10.1006/dbio.2000.9751. PMID 10882522.

Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Gudbjartsson DF, Walters GB, Thorleifsson G, et al. (2008). "Many sequence variants affecting diversity of adult human height". Nat. Genet. 40 (5): 609–15. doi:10.1038/ng.122. PMID 18391951. S2CID 3005450.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Sulem P, Gudbjartsson DF, Rafnar T, et al. (2009). "Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche". Nat. Genet. 41 (6): 734–8. doi:10.1038/ng.383. PMID 19448622. S2CID 7425600.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132429 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019848 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: popeye domain containing 3".

[pmid10882522-6] Andrée B, Hillemann T, Kessler-Icekson G, Schmitt-John T, Jockusch H, Arnold HH, Brand T (July 2000). "Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart". Dev. Biol. 223 (2): 371–82. doi:10.1006/dbio.2000.9751. PMID 10882522.

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POPDC3

Function

References

Further reading