RCL1

RCL1
Identifiers
AliasesRCL1, RNAC, RPCL1, RNA terminal phosphate cyclase like 1
External IDsOMIM: 611405; MGI: 1913275; HomoloGene: 4217; GeneCards: RCL1; OMA:RCL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001286699
NM_001286700
NM_001286701
NM_005772

NM_021525

RefSeq (protein)

NP_001273628
NP_001273629
NP_001273630
NP_005763

NP_067500

Location (UCSC)Chr 9: 4.79 – 4.89 MbChr 19: 29.08 – 29.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

RNA 3'-terminal phosphate cyclase-like protein is an enzyme that in humans is encoded by the RCL1 gene.[5]

Copy number variants to the RCL1 gene are associated with a range of neuropsychiatric phenotypes,[6] and a missense variant associated with depression.[7]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120158Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024785Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: RCL1 RNA terminal phosphate cyclase-like 1".
  6. ^ Brownstein CA, Smith RS, Rodan LH, et al. (May 2021). "RCL1 copy number variants are associated with a range of neuropsychiatric phenotypes". Molecular Psychiatry. 26 (5): 1706–1718. doi:10.1038/s41380-021-01035-y. PMC 8159744. PMID 33597717.
  7. ^ Amin N, de Vrij FM, Baghdadi M, et al. (May 2018). "A rare missense variant in RCL1 segregates with depression in extended families". Molecular Psychiatry. 23 (5): 1120–1126. doi:10.1038/mp.2017.49. PMC 5984098. PMID 28322274.

Further reading

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