Robert H. Singer

Robert H. Singer
Robert H. Singer
Born
Boston, Massachusetts
Alma materOberlin College, Brandeis University
AwardsRosenstiel Award (2021)
Scientific career
FieldsCell biology, Molecular biology
InstitutionsAlbert Einstein College of Medicine, Janelia Research Campus
Academic advisorsSheldon Penman, David Yaffe

Dr. Robert H. Singer received an undergraduate degree in physical chemistry from Oberlin College, and a PhD in developmental biology from Brandeis University.[1] He did postdoctoral work in molecular biology at the Massachusetts Institute of Technology and the Weizmann Institute of Science in Rehovot, Israel.[2] Oberlin College granted Singer an Honorary Doctor of Science in 2016.[3] The Hebrew University of Jerusalem granted Singer an Honorary Doctorate in 2018.[4][5]

Singer holds the following positions at the Albert Einstein College of Medicine, New York: Professor and Co-Chair, Department of Anatomy and Structural Biology; Professor, Dominick P. Purpura Department of Neuroscience; Professor, Department of Cell Biology; Co-Director, Integrated Imaging Facility; and Co-Director, Gruss Lipper Biophotonics Center.[6] Singer is a senior fellow at the Janelia Research Campus of the Howard Hughes Medical Institute in Virginia.[7]

Singer's career has been focused on the cell biology of RNA, its isolation, detection, expression, and translation. A patent in situ hybridization technique his lab developed for detecting RNA in morphologically preserved cells revealed that messenger RNA can localize in specific cellular compartments. This work has given rise to the field of RNA transport and localization, enhanced by Singer's and his colleagues’ development of imaging technology and RNA reporters. His lab has shown that the dynamics of RNA transcription on a single gene can be interrogated by live cell imaging, as well as by multiplexed fluorescent probes.

Singer's laboratories at Einstein and Janelia have been instrumental in developing rapid and sensitive microscopy that can study single molecules of RNA in living cells and in devising methods to track them through their life cycle. This technology has implications for understanding the role of RNA in such disease processes as cancer metastasis and intellectual disability. He holds 12 patents on his work.[8]

Singer is a member of the US National Academy of Sciences,[9] American Academy of Arts and Sciences,[10] and is a Fellow of the American Association for the Advancement of Science.[11] In 2021, he received the Rosenstiel Award.[12]

References

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  1. ^ "Seminars & Events". Archived from the original on 2016-06-12. Retrieved 2016-07-05.
  2. ^ Singer, Robert H. (16 March 2015). "Reminiscences on my life with RNA: a self-indulgent perspective". RNA. 21 (4): 508–509. doi:10.1261/rna.050922.115. PMC 4371258. PMID 25780116.
  3. ^ "Commencement 2021". 14 December 2017.
  4. ^ "Honorary Doctorates - the Hebrew University of Jerusalem". Archived from the original on 2008-10-16. Retrieved 2018-08-23.
  5. ^ "Academic Honors & Events". Albert Einstein College of Medicine. Archived from the original on September 8, 2015.
  6. ^ "Robert H. Singer, Ph.D." Albert Einstein College of Medicine. Archived from the original on April 24, 2018.
  7. ^ "Robert H. Singer, PhD". Howard Hughes Medical Institute. Archived from the original on May 27, 2016.
  8. ^ "Patents | Laboratory of Robert H. Singer, Ph.D. | Albert Einstein College of Medicine". Archived from the original on 2007-08-10. Retrieved 2016-07-05.
  9. ^ "2013 NAS Members and Foreign Associates Elected". www.nasonline.org. Archived from the original on 2024-02-15. Retrieved 2024-02-15.
  10. ^ "Members: ALPHABETICAL INDEX OF ACTIVE MEMBERS" (PDF). Bulletin of the American Academy of Arts and Sciences. 70 (1). American Academy of Arts & Sciences: 182–202. 2016. ISSN 0002-712X. JSTOR 26407302. Archived (PDF) from the original on 2018-10-09. Retrieved 2024-07-12.
  11. ^ "New AAAS Fellows Recognized for Their Contributions to Advancing Science | American Association for the Advancement of Science (AAAS)". www.aaas.org.
  12. ^ "Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research". www.brandeis.edu. Archived from the original on 2021-05-08. Retrieved 2024-02-15.
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