Protein-coding gene in the species Homo sapiens
Synaptotagmin-like protein 1 is a protein that in humans is encoded by the SYTL1 gene .[ 5] [ 6]
SYTL1 has been shown to interact with RAB27A .[ 7] [ 8] [ 9]
^ a b c GRCh38: Ensembl release 89: ENSG00000142765 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028860 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Catz SD, Babior BM, Johnson JL (November 2002). "JFC1 is transcriptionally activated by nuclear factor-kappaB and up-regulated by tumour necrosis factor alpha in prostate carcinoma cells" . The Biochemical Journal . 367 (Pt 3): 791–9. doi :10.1042/BJ20020345 . PMC 1222920 PMID 12137562 . ^ "Entrez Gene: SYTL1 synaptotagmin-like 1" .^ Fukuda M (April 2003). "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells" . The Journal of Biological Chemistry . 278 (17): 15390–6. doi :10.1074/jbc.M213090200 PMID 12590134 . ^ Strom M, Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport" . The Journal of Biological Chemistry . 277 (28): 25423–30. doi :10.1074/jbc.M202574200 PMID 11980908 . ^ Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (March 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain" . The Journal of Biological Chemistry . 277 (11): 9212–8. doi :10.1074/jbc.M112414200 PMID 11773082 . Fukuda M, Mikoshiba K (March 2001). "Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins". Biochemical and Biophysical Research Communications . 281 (5): 1226–33. doi :10.1006/bbrc.2001.4512 . PMID 11243866 . McAdara Berkowitz JK, Catz SD, Johnson JL, Ruedi JM, Thon V, Babior BM (June 2001). "JFC1, a novel tandem C2 domain-containing protein associated with the leukocyte NADPH oxidase" . The Journal of Biological Chemistry . 276 (22): 18855–62. doi :10.1074/jbc.M011167200 PMID 11278853 . Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (March 2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain" . The Journal of Biological Chemistry . 277 (11): 9212–8. doi :10.1074/jbc.M112414200 PMID 11773082 . Strom M, Hume AN, Tarafder AK, Barkagianni E, Seabra MC (July 2002). "A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport" . The Journal of Biological Chemistry . 277 (28): 25423–30. doi :10.1074/jbc.M202574200 PMID 11980908 . Fukuda M (April 2003). "Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells" . The Journal of Biological Chemistry . 278 (17): 15390–6. doi :10.1074/jbc.M213090200 PMID 12590134 . Johnson JL, Ellis BA, Noack D, Seabra MC, Catz SD (November 2005). "The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase" . The Biochemical Journal . 391 (Pt 3): 699–710. doi :10.1042/BJ20050380 . PMC 1276972 PMID 16004602 . Schmid M, Fellermann K, Fritz P, Wiedow O, Stange EF, Wehkamp J (April 2007). "Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease". Journal of Leukocyte Biology . 81 (4): 907–15. doi :10.1189/jlb.0906581 . PMID 17200145 . S2CID 30032616 . 
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