法司努单抗 - 维基百科,自由的百科全书

法司努单抗
单克隆抗体
种类?
目標HNGF英语Nerve growth factor
臨床資料
ATC碼
  • 未分配
识别信息
CAS号1190239-42-9
ChemSpider
  • none
UNII
KEGG
化学信息
化学式C6406H9896N1700O2026S46
摩尔质量144,618.27 g·mol−1

法司努单抗INN:Fasinumab)是一种人单克隆抗体,设计用于治疗急性坐骨神经痛[1][2]该药物由梯瓦制药工业有限公司再生元制药公司合作开发。目前正处于III期试验(NCT03245008、NCT02683239和NCT03161093)。[3]

参考资料

[编辑]
  1. ^ Fasinumab (PDF). Statement On A Nonproprietary Name Adopted By The USAN Council. American Medical Association. [2023-12-06]. (原始内容存档 (PDF)于2020-04-14). 
  2. ^ Tiseo PJ, Ren H, Mellis S. Fasinumab (REGN475), an antinerve growth factor monoclonal antibody, for the treatment of acute sciatic pain: results of a proof-of-concept study. Journal of Pain Research. 2014, 7: 523–530. PMC 4155988可免费查阅. PMID 25210473. doi:10.2147/JPR.S65974可免费查阅. 
  3. ^ Oo WM, Hunter DJ. Nerve Growth Factor (NGF) Inhibitors and Related Agents for Chronic Musculoskeletal Pain: A Comprehensive Review. BioDrugs. November 2021, 35 (6): 611–641. PMID 34807432. S2CID 244509341. doi:10.1007/s40259-021-00504-8.