CCRL1

ACKR4
Identifiers
AliasesACKR4, CC-CKR-11, CCBP2, CCR-11, CCR10, CCR11, CCRL1, CCX CKR, CCX-CKR, CKR-11, PPR1, VSHK1, atypical chemokine receptor 4
External IDsOMIM: 606065; MGI: 2181676; HomoloGene: 49474; GeneCards: ACKR4; OMA:ACKR4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178445
NM_016557

NM_145700

RefSeq (protein)

NP_057641
NP_848540

NP_663746

Location (UCSC)Chr 3: 132.6 – 132.62 MbChr 9: 103.96 – 104 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

C-C chemokine receptor type 11 is a protein that in humans is encoded by the CCRL1 gene.[5][6]

The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. Alternatively spliced transcript variants encoding the same protein have been described.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129048Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079355Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Khoja H, Wang G, Ng CT, Tucker J, Brown T, Shyamala V (May 2000). "Cloning of CCRL1, an orphan seven transmembrane receptor related to chemokine receptors, expressed abundantly in the heart". Gene. 246 (1–2): 229–38. doi:10.1016/S0378-1119(00)00076-7. PMID 10767544.
  6. ^ a b "Entrez Gene: CCRL1 chemokine (C-C motif) receptor-like 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.