Settlement[ nb 1] Founded, Relocated (reason) Founders Indians Languages [ 3] Comments Province Coordinates Image San José de Chiquitos 1698 Felipe Suárez, Fr. Dionisio Ávila Penoquis Chiquitano (Penoqui) Chiquitos Province 17°51′0″S 60°45′0″W / 17.85000°S 60.75000°W / -17.85000; -60.75000 San Rafael de Velasco 1695, 1701 (epidemic), 1705 (epidemic), 1719 (fire), 1750 Juan Bautista Zea, Francisco Hervás Chiquitano José Miguel de Velasco Province 16°47′13″S 60°40′26″W / 16.7869°S 60.6738°W / -16.7869; -60.6738 San Javier 1691, 1696 (incursion of Paulistas ; relocated to the San Miguel River), 1698 (Paulistas; relocated closer to Santa Cruz ), 1708 (Spanish from Santa Cruz capturing Indians; relocated away from Santa Cruz ) José de Arce, (Antonio de Rivas?) Piñocas Chiquitano (Piñoco) Ñuflo de Chávez Province 16°16′29″S 62°30′26″W / 16.2748°S 62.5072°W / -16.2748; -62.5072 San Miguel de Velasco 1721 Felipe Suárez, (Francisco Hervás) Migueleño Chiquitano Founded because San Rafael was growing too big José Miguel de Velasco Province 16°41′54.96″S 60°58′5.16″W / 16.6986000°S 60.9681000°W / -16.6986000; -60.9681000 Concepción 1699, 1707, 1708, 1722 Francisco Lucas Caballero, Francisco Hervás Chiquitanos Chiquitano (Bésɨro) Ñuflo de Chávez Province 16°07′55″S 62°01′34″W / 16.13194°S 62.02611°W / -16.13194; -62.02611 Santa Ana de Velasco 1755 Julian Knogler Covarecas and Curuminacas Otuke (Covareca, Curuminaca) José Miguel de Velasco Province 16°35′1″S 60°41′16″W / 16.58361°S 60.68778°W / -16.58361; -60.68778 San Ignacio de Velasco 1748 Diego Contreras, Michael Streicher (also known as Areijer) Ugaraños Ignaciano Chiquitano Partially settled by inhabitants of former San Ignacio de Zamucos José Miguel de Velasco Province 16°22′0″S 60°57′0″W / 16.36667°S 60.95000°W / -16.36667; -60.95000 San Juan Bautista 1699, 1705 (epidemic)-closed,[ nb 2] reopened in 1713 in a new location Juan Bautista Zea, Juan Patricio Fernández Suberecas, Petas, Piñocas Chiquitano (Piñoco) Founded because San José had grown too big Chiquitos Province 17°54′S 60°22′W / 17.900°S 60.367°W / -17.900; -60.367 San Ignacio de Zamucos 1716 (attempts of founding), 1723; abandoned in 1745 (fights between Zamucos and Ugarone) Felipe Suárez, Juan Bautista Zea, Agustín Castañares Ayoreo Cordillera Province 19°10′S 60°38′W / 19.167°S 60.633°W / -19.167; -60.633 Santo Corazón 1760, 1788 Antonio Gaspar, José Chueca Otukes Otuke Ángel Sandoval Province 17°58′S 58°48′W / 17.967°S 58.800°W / -17.967; -58.800 Santiago de Chiquitos 1754, 1764 Gaspar Troncoso, Gaspar Campos Santiagueño Chiquitano Chiquitos Province 18°20′24″S 59°35′54″W / 18.34000°S 59.59833°W / -18.34000; -59.59833