OR10A4

OR10A4
Identifiers
Aliases	OR10A4, JCG5, OR10A4P, olfactory receptor family 10 subfamily A member 4
External IDs	MGI: 109148; HomoloGene: 23241; GeneCards: OR10A4; OMA:OR10A4 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,877,619 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	106,699,015 bp
RNA expression pattern
	Top expressed in
	testicle; ; bone marrow cells; ; corpus callosum; ; placenta;
	Top expressed in
	respiratory epithelium; ; nasal epithelium; ; olfactory epithelium; ; gastrula;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; axon guidance; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	283297
	18314
	ENSG00000170782
	ENSMUSG00000073897
	Q9H209
	Q7TRM9
	NM_207186
	NM_020598
	NP_997069
	NP_065623
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 10A4 is a protein that in humans is encoded by the OR10A4 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170782 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000073897 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR10A4 olfactory receptor, family 10, subfamily A, member 4".

External links

OR10A4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170782 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000073897 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR10A4 olfactory receptor, family 10, subfamily A, member 4".

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OR10A4

See also

References

Further reading

External links