List of state highways in South Carolina

This article relies largely or entirely on a single source. Relevant discussion may be found on the talk page. Please help improve this article by introducing citations to additional sources. Find sources: "List of state highways in South Carolina" – news · newspapers · books · scholar · JSTOR (September 2020)

This article may be too long to read and navigate comfortably. Consider splitting content into sub-articles, condensing it, or adding subheadings. Please discuss this issue on the article's talk page. (July 2022)

State Highways of South Carolina
Highway marker of SC 9, SC 34, and SC 121
System information
Maintained by SCDOT
Length	41,414 mi[1] (66,649 km)
Formed	1922 (1922)
State	South Carolina Highway nn (SC nn)
System links
South Carolina State Highway System Interstate US State Scenic

This is a List of state highways in South Carolina. These state highways are owned and maintained by the U.S. state of South Carolina, through the South Carolina Department of Transportation (SCDOT).

Since its establishment, there have been countless removals and reestablishment of highways in the state (check notes for current or last form count). Typically, it is that one highway wins favor over another, while the other highway is either absorbed or downgraded to a secondary road.

Number	Length (mi)	Length (km)	Southern or western terminus	Northern or eastern terminus	Formed	Removed	Notes
SC 1	—	—	Georgia state line southwest of Limehouse	SC 12 in West Columbia	01922-01-011922	01928-01-011928
SC 2	3.940	6.341	US 21/US 176/US 321 in Cayce	US 378 in West Columbia	01922-01-011922	current
SC 3	—	—	SC 50 in Columbia	NC 202 at the North Carolina state line near Nichols	01922-01-011922	01928-01-011928	First form
SC 3	96.310	154.996	US 278 / Mill Pond Road in Grays	US 321 in Swansea	01928-01-011928	current	Second form
SC 4	54.430	87.597	US 78 east of Aiken	US 21 / US 21 Bus. / US 601 Truck near Wilkinson Heights	01922-01-011922	current
SC 5	51.719	83.234	US 521 near Van Wyck	I-85 / SC 198 in Blacksburg	01922-01-011922	current
SC 6	116.092	186.832	US 76 in Ballentine	US 52 / SC 6 Truck / Main Street Extension in Moncks Corner	01922-01-011922	current
SC 7	—	—	Georgia state line southwest of Calhoun Falls	NC 51 at the North Carolina state line near Fort Mill	01922-01-011922	01942-01-011942	First form
SC 7	5.920	9.527	US 17 in Charleston	US 52 / US 78 in North Charleston	01956-01-011956	current	Second form
SC 8	—	—	SR 8 at the Georgia state line near Starr	US 29 at the North Carolina state line northeast of Blacksburg	01922-01-011922	01927-01-011927	First form
SC 8	44.030	70.859	US 276 west of Cleveland	US 25 / SC 418 in Ware Place	01928-01-011928	current	Second form
SC 9	259.570	417.737	SC 65 in Cherry Grove Beach	NC 9 at the North Carolina state line near Fingerville	01922-01-011922	current
SC 10	22.790	36.677	SC 28 northwest of McCormick	US 25 Bus. / US 178 / SC 34 in Greenwood	01922-01-011922	current
SC 11	119.850	192.880	I-85 southwest of Fair Play	SC 150 in Gaffney	01922-01-011922	current
SC 12	—	—	Georgia state line south of North Augusta	SC 2 in West Columbia	01922-01-011922	01928-01-011928	First form
SC 12	—	—	SC 26 in Hancock	NC 25 at the North Carolina state line northeast of Hancock	01929-01-011929	01938-01-011938	Second form
SC 12	28.250	45.464	US 1 in West Columbia	I-20 / US 601 south of Lugoff	01940-01-011940	current	Third form
SC 13	—	—	SC 14 in Pickens	SC 2 in Easley	01922-01-011922	01928-01-011928	First form
SC 13	—	—	SR 13 at the Georgia state line southwest of Westminster	Greenville	01928-01-011928	01946-01-011946	Second form
SC 14	—	—	SC 15 in Anderson	NC 283 at the North Carolina state line near Rocky Bottom	01922-01-011922	01937-01-011937	First form
SC 14	59.240	95.338	US 76 Bus. in Laurens	I-26 / Landrum Road in Landrum	01942-01-011942	current	Second form
SC 15	—	—	SC 2 in Calhoun	SC 92 near Cross Anchor	01922-01-011922	01935-01-011935
SC 16	—	—	SC 2 in Columbia	NC 16 at the North Carolina state line northeast of Bowling Green	01922-01-011922	01931-01-011931	First form
SC 16	—	—	SC 48 in Columbia	SC 12 in Columbia	01939-01-011939	01948-01-011948	Second form
SC 16	9.550	15.369	SC 48 in Columbia	US 176 / Clement Road in Columbia	01964-01-011964	current	Third form
SC 17	—	—	SR 17 at the Georgia state line southwest of Westminster	SC 2 in Seneca	01922-01-011922	01928-01-011928
SC 18	—	—	SC 20 in Abbeville	Georgia state line northwest of Long Creek	01922-01-011922	01938-01-011938	First form
SC 18	39.040	62.829	US 176 / SC 18 Truck / SC 215 in Union	NC 18 at the North Carolina state line near Blacksburg	01938-01-011938	current	Second form
SC 19	28.750	46.269	Savannah River Site south of New Ellenton	US 25 / SC 121 southwest of Trenton	01922-01-011922	current
SC 20	53.210	85.633	Washington Street / Trinity Street in Abbeville	McBee Avenue / River Street / Richardson Street in Greenville	01922-01-011922	current
SC 21	—	—	Georgia state line at North Augusta	North Carolina state line near Cleveland	01922-01-011922	01928-01-011928
SC 22	—	—	SC 21 in Greenwood	SC 97 in Great Falls	01922-01-011922	01952-01-011952	First form
SC 22	29.390	47.299	US 501 near Cool Spring	US 17 / Kings Road west of Briarcliff Acres	02001-01-012001	current	Second form; projected to become part of I-73
SC 23	—	—	SC 3 in Pee Dee	NC 22 at the North Carolina state line near Dillon	01922-01-011922	01928-01-011928	First form
SC 23	47.060	75.736	US 221 / SC 28 in Modoc	US 1 in Batesburg–Leesville	01929-01-01c. 1929	current	Second form
SC 24	—	—	Georgia state line near Mountain Rest	US 78 east of Dorchester	01922-01-011922	01938-01-011938	First form
SC 24	30.660	49.342	US 76 / US 123 / Oak Street in Westminster	US 29 Bus. / US 76 / US 178 / SC 28 Bus. / SC 81 in Anderson	01938-01-011938	current	Second form
SC 25	—	—	SC 21 in Hodges	SC 20 in Donalds	01922-01-011922	01929-01-011929
SC 26	—	—	SC 40 north of Georgetown	North Carolina state line near Fort Mill	01922-01-011922	01933-01-011933	First form
SC 26	—	—	US 301 in Orangeburg	US 1 in Lugoff	01935-01-011935	01951-01-011951	Second form
SC 27	—	—	SC 19 / SC 21 in Trenton	SC 2 east of Dorchester	01922-01-011922	01927-01-011927	First form
SC 27	19.511	31.400	SC 61 in Givhans	US 176 near Sandridge	01929-01-01c. 1929	current	Second form
SC 28	131.220	211.178	SR 28 at the Georgia state line near Mountain Rest SR 28 at the Georgia state line northwest of Beech Island	SR 28 at the Georgia state line near Clarks Hill US 278 / SC 125 in Beech Island	01922-01-011922	current
SC 28Y	—	—	SC 72 southwest of Abbeville	SC 28 southwest of Abbeville	01941-01-01c. 1941	01957-01-011957
SC 28Y	—	—	SC 28 in Yemassee	US 17/US 21 in Yemassee	01938-01-011938	01947-01-011947
SC 29	—	—	SC 21 in Travelers Rest	North Carolina state line near Cleveland	01922-01-011922	01925-01-01c. 1925
SC 30	—	—	Beaufort	North Carolina state line near McColl	01922-01-011922	01933-01-011933	First form
SC 30	—	—	US 221 in Watts Mills	SC 92 near Cross Anchor	01935-01-011935	01956-01-011956	Second form
SC 30	3.050	4.908	SC 171 in James Island	Lockwood Drive in Charleston	01995-01-01c. 1995	current	Third form; projected to become part of an extension of I-526
SC 31	—	—	—	Goose Creek	01922-01-011922	01951-01-011951	First form
SC 31	—	—	SC 7 in Charleston	SC 642 in North Charleston	01985-01-01c. 1985	01990-01-01c. 1990	Second form
SC 31	28.097	45.218	SC 707 near Socastee	SC 9 in Little River	02002-01-01c. 2002	current	Third form; projected to become part of I-74
SC 32	—	—	SC 30 near Henderson	SC 6 near Jacksonboro	01922-01-011922	01925-01-01c. 1925
SC 32	—	—	SC 30 in Gardens Corner	SC 6 in Jacksonboro	01926-01-01c. 1926	01951-01-011951
SC 33	19.360	31.157	US 301 / US 601 / SC 4 / Andrew Dibble Street in Orangeburg	SC 267 northwest of Lone Star	01922-01-011922	current
SC 34	185.930	299.225	US 25 Bus. / US 178 Bus. / SC 10 in Greenwood	US 301 / US 501 / SC 9 / SC 57 in Dillon	01922-01-011922	current
SC 35	—	—	SC 41 in Darlington	North Carolina state line near Pageland	01922-01-011922	01938-01-011938	First form
SC 35	5.630	9.061	I-77 in Cayce	US 378 / Seminole Drive in Columbia	01996-01-01c. 1996	current	Second form
SC 36	—	—	Near Ridgeland	US 21 in Rowesville	01922-01-011922	01951-01-011951
SC 37	15.430	24.832	US 278 north of Barnwell	SC 39 southwest of Springfield	01922-01-011922	current
SC 38	43.694	70.319	US 501 east of Sellers	NC 38 at the North Carolina state line near Bennettsville	01922-01-011922	current
SC 39	100.889	162.365	US 278 / Savannah Drive southwest of Williston	US 221 in Cold Point	01922-01-011922	current
SC 40	—	—	US 17 / US 78 / SC 2 in Charleston	North Carolina state line north of Loris	01922-01-011922	01933-01-011933
SC 41	—	—	SC 2 near Goose Creek	SC 50 near Cheraw at the North Carolina state line northeast of Lake View	01922-01-011922	01928-01-011928	First form
SC 41	—	—	US 301 near New Zion	New Zion	01935-01-01c. 1935	01938-01-011938	Second form
SC 41	121.5	195.5	US 17 / Dingle Road in Mount Pleasant	NC 41 at the North Carolina state line northeast of Lake View	01938-01-011938	current	Third form
SC 42	—	—	SC 3 in Sumter	SC 34 in Bishopville	01922-01-011922	01925-01-01c. 1925	First form
SC 42	—	—	SC 33 northeast of Cope	SC 4 in Orangeburg	01937-01-011937	01947-01-011947	Second form
SC 43	—	—	SR 70 at the Georgia state line southwest of McCormick	US 1 / US 21 / SC 2 / SC 5 / SC 215 in West Columbia	01923-01-011923	01952-01-011952
SC 44	—	—	SC 41 west of Gourdin	SC 40 in Georgetown	01922-01-011922	01928-01-011928
SC 44	—	—	SC 261 in Sanders Corner	SC 30 in Mannville	01928-01-01c. 1928	01947-01-011947
SC 45	76.060	122.407	US 17 / South Pinckney Street in McClellanville	US 15 / US 176 in Wells	01923-01-011923	current
SC 46	—	—	SC 45 in Ferguson	SC 41 in Moncks Corner	01923-01-01c. 1923	01939-01-011939	First form
SC 46	17.330	27.890	US 321 northwest of Hardeeville	US 278 / Waterford Drive east of Bluffton	01939-01-011939	current	Second form
SC 46Y	—	—	US 17 in Hardeeville	SC 46 in Hardeeville	01939-01-01c. 1939	01942-01-01c. 1942
SC 47	—	—	SC 40 in Green Sea	NC 21 at the North Carolina state line northeast of Lake View	01923-01-01c. 1923	01925-01-01c. 1925	First form
SC 47	5.740	9.238	US 301 east of Oaks Crossroads	SC 6 / SC 47 Truck / SC 267 in Elloree	01929-01-01c. 1929	current	Second form
SC 48	28.980	46.639	US 21 / US 76 / US 176 / US 321 in Columbia	US 601 in Wateree	01930-01-011930	current
SC 49	—	—	SC 26 / SC 40 in Georgetown	NC 30 at the North Carolina state line near Little River	01929-01-01c. 1929	01935-01-011935	First form
SC 49	79.516	127.969	US 221 / Smith Road in Watts Mills	NC 49 at the North Carolina state line in Lake Wylie	01938-01-011938	current	Second form
SC 50	—	—	SC 2 in Columbia	NC 50 at the North Carolina state line near Wallace	01922-01-011922	01928-01-011928	First form
SC 50	—	—	US 21 / SC 5 in Rock Hill	Mill Street in Rock Hill	01942-01-01c. 1942	01947-01-011947	Second form
SC 51	70.65	113.70	US 701 north of Georgetown US 21 north of Fort Mill	US 76 / Evans Street in Florence NC 51 at the North Carolina state line near Fort Mill	01926-01-01c. 1926	current
SC 52	—	—	SC 31 / SC 45 in St. Matthews	SC 3 near Eastover	01926-01-01c. 1926	01935-01-011935
SC 53	11.900	19.151	US 378 southwest of Shiloh	SC 403 in Hobbs Crossroads	01926-01-01c. 1926	current
SC 54	—	—	SC 3 in Sumter	SC 51 in Salem	01926-01-01c. 1926	01951-01-011951
SC 55	—	—	SC 21 near Greenwod	SC 24 in Friendship	01926-01-01c. 1926	01929-01-011929	First form
SC 55	20.990	33.780	SC 5 near Kings Creek	SC 49 / SC 274 / Lake Wylie Road southwest of Lake Wylie	01929-01-011929	current	Second form
SC 56	67.300	108.309	SC 39 near Chappells	US 176 on the Southern Shops–Valley Falls line	01926-01-01c. 1926	current
SC 57	25.880	41.650	SC 41 / SC 41 Alt. in Fork	Fairley Road at the North Carolina state line northeast of Minturn	01929-01-01c. 1929	current
SC 58	—	—	SC 163 west of Lake Wylie	North Carolina state line northwest of Lake Wylie	01929-01-011929	01942-01-011942	First form
SC 58	12.520	20.149	SC 341 in South Lynchburg	US 301 / US 378 in Turbeville	01940-01-011940	current	Second form
SC 59	—	—	SC 55 east of Clover	SC 58 / SC 163 near Lake Wylie	01929-01-011929	01942-01-011942	First form
SC 59	15.697	25.262	I-85 / Lakeshore Drive southwest of Fair Play	US 76 / US 123 / SC 28 in Seneca	01942-01-011942	current	Second form
SC 60	5.160	8.304	SC 6 / Bush River Road southwest of Irmo	US 176 on the St. Andrews–Columbia line	01929-01-01c. 1929	current
SC 61	67.05	107.91	SC 30 in Charleston	US 78 near Farrells Crossroads	01923-01-011923	current
SC 62	—	—	SC 6 in Red Top	SC 61 north of Johns Island	01923-01-011923	01936-01-011936	First form
SC 62	—	—	US 76 / SC 2 near Ballentine	St. Andrews	01940-01-011940	01947-01-011947	Second form
SC 63	28.200	45.384	US 278 / Hickory Hill Road in Varnville	SC 64 Bus. in Walterboro	01924-01-01c. 1924	current
SC 64	73.730	118.657	Dunbarton Boulevard / Technology Drive in Snelling	US 17 in Jacksonboro	01926-01-01c. 1926	current
SC 64Y	—	—	SC 64 in Round O	North of Round O	01939-01-01c. 1939	01942-01-01c. 1942
SC 65	—	—	US 78 near Branchville	SC 61 in Cooks Crossroads	01929-01-011929	01952-01-011952	First form
SC 65	4.710	7.580	US 17 in North Myrtle Beach	SC 9 in Cherry Grove Beach	01981-01-011981	current	Second form
SC 66	18.550	29.853	SC 56 southwest of Joanna	SC 72 in Whitmire	01933-01-011933	current
SC 67	15.460	24.880	US 378 / Walker Road east of McCormick	US 25 / US 178 near Greenwood	01934-01-011934	current
SC 68	—	—	SC 381 near Clio	North Carolina state line northeast of Clio	01935-01-01c. 1935	01938-01-011938	First form
SC 68	—	—	US 78 in Denmark	Voorhees College in Denmark	01938-01-011938	01947-01-011947	Second form
SC 68	15.330	24.671	US 278 in Almeda	US 17 Alt. / US 17 Conn. / US 21 in Yemassee	01965-01-011965	current	Third form
SC 69	—	—	SC 4 in Orangeburg	SC 31 in Cameron	01935-01-01c. 1935	01938-01-011938	First form
SC 69	—	—	SC 546 southwest of Pelion	SC 6 in Swansea	01939-01-011939	01947-01-011947	Second form
SC 69	—	—	US 17 in Atlantic Beach	US 17 in Cherry Grove Beach	01977-01-011977	01981-01-011981	Third form
SC 70	29.990	48.264	US 278 / SC 64 in Barnwell	US 301 / US 601 northwest of Cordova	01936-01-011936	current
SC 71	14.980	24.108	SC 20 in Abbeville	SC 81 east of Lowndesville	01926-01-01c. 1926	current
SC 72	—	—	SC 7 southwest of Cross Hill	SC 10 in Waterloo	01926-01-01c. 1926	01932-01-011932	First form
SC 72	—	—	SC 7 near Leeds	Leeds	01940-01-011940	01942-01-011942	Second form
SC 72	124.860	200.943	SR 72 at the Georgia state line southwest of Calhoun Falls	SC 122 in Rock Hill	01942-01-011942	current	Third form
SC 73	—	—	SC 7 in Fort Mill	SC 26 in Indian Land	01926-01-01c. 1926	01928-01-011928
SC 73	—	—	SC 38 in Brownsville	SC 9 in Dillon	01932-01-011932	01939-01-011939
SC 73	—	—	US 301 / US 501 in Latta	SC 57 near Fork	01939-01-011939	01942-01-011942
SC 73	—	—	SR 73 at the Georgia state line southwest of Allendale	SC 5 / SC 641 in Sycamore	01942-01-011942	01947-01-011947
SC 73	—	—	US 17 Bus. in Springmaid Beach	US 17 Bus. in Myrtle Beach	01960-01-011960	02006-01-012006
SC 75	8.110	13.052	SC 5 / SC 75 Truck / Riverside Road in Van Wyck	NC 75 at the North Carolina state line near Lesslie	01938-01-011938	current
SC 77	—	—	SC 9 in Hickson	NC 77 at the North Carolina state line near Wallace	01938-01-011938	01961-01-011961	First form
SC 77	—	—	US 76 / US 378 in Columbia	I-20 on the Woodfield–Dentsville line	01981-01-011981	01982-01-011982	Second form; became part of I-77
SC 79	—	—	SC 6 in Denmark	Voorhees College in Denmark	01935-01-01c. 1935	01938-01-011938	First form
SC 79	9.340	15.031	SC 9 / Brickyard Road near Bennettsville	NC 79 at the North Carolina state line near McColl	01938-01-011938	current	Second form
SC 80	—	—	SC 181 in Fair Play	SC 18 in Anderson	01937-01-011937	01962-01-011962	First form
SC 80	5.620	9.045	SC 14 / SC 101 Truck / Tandem Drive in Greer	US 29 / SC 290 Truck / Gary Armstrong Road in Greer	02002-01-012002	current	Second form
SC 81	80.890	130.180	SC 28 near Lethia	SC 124 in Greenville	01926-01-01c. 1926	current
SC 82	—	—	SC 20 near Lethia	SC 81 in Starr	01928-01-011928	01949-01-011949
SC 83	4.820	7.757	SC 381 northeast of Clio	NC 83 at the North Carolina state line northeast of Clio	01938-01-011938	current
SC 84	—	—	US 276 in Caesars Head State Park at the North Carolina state line northwest of Cleveland Solomon Jones Road in Jones Gap State Park at the North Carolina state line northwest of Cleveland	Solomon Jones Road in Caesars Head State Park at the North Carolina northwest of Cleveland YMCA Camp Greenville in Jones Gap State Park northwest of Cleveland	01935-01-01c. 1935	01947-01-011947
SC 85	—	—	SC 8 / SC 81 near Piedmont	US 29 in Piedmont	01937-01-011937	01938-01-011938
SC 85	—	—	US 1 near McBee	NC 85 at the North Carolina state line near Chesterfield	01938-01-011938	01961-01-011961
SC 86	12.090	19.457	SC 8 / Sitton Road south of Easley	US 25 / Sandy Springs Road southeast of Golden Grove	01938-01-011938	current
SC 87	—	—	SC 13 in Central	SC 81 northwest of Aaron	01940-01-011940	01947-01-011947
SC 88	14.350	23.094	North Broad Street in Pendleton	SC 8 west of Piedmont	01939-01-011939	current	Signed to begin at SC 28 Bus. in Pendleton
SC 89	—	—	SC 8 in Easley	SC 135 in Easley	01940-01-011940	01947-01-011947
SC 90	23.110	37.192	US 378 Truck / US 501 Bus. / US 701 Truck / SC 90 Truck in Red Hill	US 17 / Fairway Drive in Little River	01929-01-011929	current
SC 91	—	—	SC 92 in Monarch Mill	Black Highway northwest of York	01923-01-011923	01956-01-011956
SC 92	16.460	26.490	SC 101 in Gray Court	SC 49 southwest of Cross Anchor	01926-01-01c. 1926	current
SC 93	—	—	SC 97 northeast of Great Falls	NC 200 at the North Carolina state line near Lancaster	01926-01-01c. 1926	01952-01-011952
SC 93	19.760	31.801	US 76 / SC 28 in Clemson	US 123 in Easley	01964-01-011964	current
SC 94	—	—	SC 9 in Lake View	North Carolina state line northeast of Lake View	01926-01-01c. 1926	01938-01-011938	First form
SC 94	—	—	SC 54 northwest of New Zion	SC 175 in Coopers	01938-01-011938	01947-01-011947	Second form
SC 95	—	—	US 1 near McBee	NC 85 at the North Carolina state line near Chesterfield	01926-01-01c. 1926	01938-01-011938	First form
SC 95	—	—	SC 9 in Little Rock	Fairley Road at the North Carolina state line east of Clio	01939-01-011939	01952-01-011952	Second form
SC 96	—	—	US 1 / SC 9 in Cheraw	NC 80 at the North Carolina state line near Cheraw	01926-01-011926	01933-01-011933	First form
SC 96	—	—	SC 9 northwest of Bennettsville	North Carolina state line north of Bennettsville	01932-01-011932	01938-01-011938	Second form
SC 96	—	—	US 521 near Lancaster SC 9 near Taxahaw	SC 906 near Taxahaw SC 943 near Taxahaw	01940-01-011940	01947-01-011947	Third form
SC 97	89.800	144.519	US 521 / US 601 in Camden	SC 5 in Kings Creek	01926-01-01c. 1926	current
SC 98	—	—	US 1 / SC 9 in Kollock	NC 77 at the North Carolina state line near Wallace	01928-01-011928	01938-01-011938	First form
SC 98	—	—	SC 91 south of Robat	SC 18 near Pacolet	01940-01-011940	01956-01-011956	Second form
SC 99	9.220	14.838	US 21 / SC 200 in Great Falls	SC 9 southeast of Richburg	01936-01-011936	current
SC 100	—	—	US 1 southwest of Cheraw	SC 9 west of Chesterfield	01940-01-011940	01947-01-011947
SC 101	56.522	90.963	US 76 / Neeley Ferry Road in Hickory Tavern	SC 11 / Highway 912 near Tigerville	01928-01-011928	current
SC 102	25.550	41.119	US 15 Bus. / US 15 Truck / Patrick Highway in North Hartsville	SC 9 in Chesterfield	01936-01-011936	current
SC 103	—	—	SC 114 southeast of Gaffney	North Carolina state line near Gaffney	01937-01-011937	01947-01-011947
SC 104	—	—	SC 43 in McCormick	SC 10 northeast of Troy	01939-01-011939	01947-01-011947
SC 105	33.220	53.462	SC 49 south of Robat	I-85 / Hyatt Street in Gaffney	01940-01-011940	current
SC 106	—	—	Kathwood	SC 391 northeast of Aiken	01940-01-011940	01947-01-011947
SC 107	15.290	24.607	SC 28 near Mountain Rest	NC 107 at the North Carolina state line near Salem	01940-01-011940	current
SC 108	—	—	SC 100 southwest of Cheraw	SC 9 in Cheraw	01940-01-011940	01947-01-011947
SC 109	14.520	23.368	SC 145 / Hartsville–Ruby Road in Campbell Crossroads	NC 109 at the North Carolina state line near Mount Croghan	01935-01-01c. 1935	current
SC 110	—	—	US 221 in Chesnee	NC 741 at the North Carolina state line near Chesnee	01931-01-011931	01942-01-011942	First form
SC 110	9.280	14.935	US 29 in Cowpens	US 221 Alt. / SC 11 near Chesnee	01942-01-011942	current	Second form
SC 111	—	—	US 29 in Gaffney	NC 18 at the North Carolina state line northeast of Gaffney	01928-01-01c. 1928	01938-01-011938	First form
SC 111	—	—	SC 113 in Gilbert	SC 386 in Ridge Crossroads	01940-01-011940	01947-01-011947	Second form
SC 112	—	—	SC 9 in New Prospect	US 221 / SC 110 in Chesnee	01936-01-011936	01939-01-011939	First form
SC 112	—	—	SC 215 / SC 215 Alt. in Carlisle	SC 115 in Mean Crossroads	01940-01-011940	01947-01-011947	Second form
SC 113	13.610	21.903	SC 394 / South Dixie Road west of Salley	US 178 / Calks Ferry Road in Fairview Crossroads	01937-01-011937	current
SC 114	6.360	10.235	SC 18 north of Bonham	SC 18 / Jerusalem Road northeast of Jonesville	01939-01-011939	current
SC 115	—	—	US 176 in West Springs	SC 9 in Jonesville	01939-01-011939	01947-01-011947
SC 116	—	—	US 1 in Leesville	SC 113 near Gilbert	01940-01-011940	01947-01-011947
SC 116	3.400	5.472	Laurel Bay Road / Joe Frazier Road in Laurel Bay	US 21 / Geiger Boulevard at Marine Corps Air Station Beaufort on the Burton–Beaufort line	01961-01-011961	current
SC 117	—	—	SC 605 near Orangeburg	SC 235 near Fort Motte	01940-01-011940	01947-01-011947
SC 118	—	—	US 1 near Camden	US 1 in Cassatt	01940-01-011940	01947-01-011947	First form
SC 118	13.180	21.211	SC 19 Truck / SC 302 in Aiken	US 78 Truck / SC 4 / SC 302 east of Aiken	01974-01-011974	current	Second form; signed as a beltway around Aiken, but is only official on alignment shown
SC 119	—	—	SC 11 northwest of Gaffney	North Carolina state line northeast of Chesnee	01942-01-011942	01947-01-011947	First form
SC 119	5.990	9.640	SR 119 at the Georgia state line near Garnett	US 321 in Garnett	01960-01-011960	current	Second form
SC 120	17.390	27.986	SC 261 in Pinewood	US 76 / US 378 in Sumter	01942-01-011942	current
SC 121	—	—	SC 27 in Aiken	SC 12 in West Columbia	01926-01-01c. 1926	01928-01-011928	First form
SC 121	—	—	SC 362 northeast of Ehrhardt	SC 6 in Vance	01929-01-011929	01964-01-011964	Second form
SC 121	134.200	215.974	US 1 / US 25 / US 78 / US 278 / SR 10 / SR 121 at the Georgia state line south of North Augusta	US 21 / SC 322 in Rock Hill	01964-01-011964	current	Third form; northern part of a multi-state highway that also exists in Florida and Georgia
SC 122	—	—	SC 2 in Cayce	US 1 / US 21 / SC 2 / SC 5 / SC 43 / SC 215 in West Columbia	01942-01-011942	01947-01-011947	First form
SC 122	5.740	9.238	SC 72 / South Elizabeth Lane in Rock Hill	Waterford Park Drive in Rock Hill	01975-01-011975	current	Second form
SC 123	—	—	SC 13 near Madison	SC 183 near Madison	01942-01-011942	01947-01-011947
SC 124	—	—	US 1 / US 76 in Columbia	US  in Dentsville	01942-01-011942	01947-01-011947	First form
SC 124	5.630	9.061	US 123 north of Powdersville	South Main Street in Greenville	01969-01-01c. 1969	current	Second form
SC 125	56.212	90.464	US 278 / US 301 in Allendale	US 25 Bus. / SC 125 Truck in North Augusta	01936-01-011936	current
SC 126	4.200	6.759	US 25 / SC 121 / Elizabeth Avenue in Belvedere	SC 421 in Clearwater	01937-01-011937	current
SC 127	—	—	SC 9 in White Stone	US 29 near Converse	01942-01-011942	01947-01-011947	First form
SC 127	3.620	5.826	US 221 / US 221 Truck south of Laurens	US 76 / US 76 Bus. / US 221 Truck in Laurens	01967-01-01c. 1967	current	Second form; completely concurrent with US 221 Truck
SC 128	—	—	SC 170 in Old House	SC 28 in Almeda	01940-01-011940	01966-01-011966	First form
SC 128	2.110	3.396	SC 170 in Port Royal	US 21 in Port Royal	02012-01-012012	current	Second form
SC 129	4.970	7.998	Falling Creek Road east of Wellford	US 29 / SC 292 / Locust Street in Lyman	01962-01-011962	current
SC 130	30.072	48.396	SC 59 in Seneca	NC 281 at the North Carolina state line near Salem	01937-01-01c. 1937	current
SC 131	—	—	US 76 / SC 13 / SC 24 in Seneca	SC 289 in Calhoun	01937-01-01c. 1937	01947-01-011947
SC 132	—	—	SC 13 in Greenville	US 25 Alt. north of Greenville	01937-01-011937	01947-01-011947	First form
SC 132	—	—	US 321 near Chester	SC 72 / SC 72 Bus. / SC 121 SC 121 Bus. northeast of Chester	01975-01-01c. 1975	01981-01-01c. 1981	Second form
SC 133	20.540	33.056	US 76 / US 123 / SC 28 in Clemson	SC 11 in Keowee-Toxaway State Park near Salem	01937-01-011937	current
SC 134	—	—	US 76 / SC 13 / SC 28 in Seneca	SC 183 northeast of West Union	01938-01-011938	01947-01-011947
SC 135	20.920	33.667	US 178 near Liberty	SC 9 south of Pumpkintown	01939-01-011939	current
SC 136	—	—	SC 133 in Calhoun	SC 13 in Calhoun	01940-01-011940	01947-01-011947
SC 137	8.410	13.535	SC 93 in Norris	SC 183 near Six Mile	01940-01-011940	current
SC 138	—	—	SC 182 near Oakway	US 76 / SC 13 in Westminster	01940-01-011940	01947-01-011947
SC 139	—	—	US 76 / SC 13 / SC 28 northeast of Seneca SC 133 near Calhoun	Oconee–Pickens county line northeast of Seneca SC 88 southeast of Central	01940-01-011940	01953-01-011953
SC 140	—	—	US 15 in Hartsville	Darlington–Chesterfield county line northwest of Hartsville	01942-01-011942	01947-01-011947
SC 141	—	—	US 76 near Horrell Hill	SC 262 near Horrell Hill	01942-01-011942	01947-01-011947
SC 145	—	—	SC 644 near Walterboro	US 15 near Walterboro	01942-01-011942	01946-01-011946	First form
SC 145	26.150	42.084	US 1 near McBee	NC 145 at the North Carolina state line near Chesterfield	01961-01-011961	current	Second form
SC 146	33.447	53.828	US 276 in Greenville	SC 56 in Cross Anchor	01942-01-011942	current
SC 147	—	—	US 1 in McBee	SC 151 in Pine Ridge	01942-01-011942	01947-01-011947
SC 149	—	—	SC 102 near Hartsville	US 15 north of Dovesville	01942-01-011942	01947-01-011947
SC 150	33.580	54.042	SC 56 near Glenn Springs	NC 150 at the North Carolina state line near Gaffney	01940-01-011940	current
SC 151	—	—	SC 15 in Anderson	SC 20 in Williamston	01926-01-01c. 1926	01929-01-011929	First form
SC 151	52.850	85.054	US 52 Bus. / SC 34 in Darlington	US 601 / SC 151 Bus. in Pageland	01938-01-011938	current	Second form
SC 152	—	—	SC 15 / SC 20 in Belton	SC 21 in Ware Place	01926-01-011926	01929-01-011929	First form
SC 152	—	—	SC 121 east of Bowman	US 178 / SC 2 near Dorchester	01937-01-011937	01947-01-011947	Second form
SC 153	—	—	SC 344 southwest of Lucknow SC 341 near Lucknow	SC 348 in Lucknow SC 151 west of Hartsville	01940-01-011940	01947-01-011947	First form
SC 153	11.510	18.524	Brown Road / Old Cleveland Street north of Golden Grove	Saluda Dam Road northeast of Easley	01974-01-011974	current	Second form
SC 154	16.680	26.844	US 76 / Mayes Open Road in Mayesville	US 15 in Bishopville	01939-01-011939	current
SC 155	—	—	SC 34 / SC 151 west of Darlington	Carolina Avenue / Floyds Road in Auburn	01940-01-011940	01947-01-011947
SC 156	—	—	Fields Bridge Road near Cypress Crossroads	SC 153 in Ashland	01940-01-011940	01947-01-011947
SC 157	—	—	SC 151 southwest of Angelus	Angelus	01940-01-011940	01942-01-011942	First form
SC 157	10.210	16.431	SC 157 Truck / SC 341 / SC 341 Truck in Kershaw	SC 346 near Catarrh	01942-01-011942	current	Second form
SC 158	—	—	Rimini	SC 260 in Jordan	01940-01-011940	01947-01-011947
SC 159	—	—	Sandy Grove Church Road in Cypress Crossroads	US 15 / SC 34 near Alcot	01940-01-011940	01947-01-011947
SC 160	11.040	17.767	NC 160 at the North Carolina state line northwest of Fort Mill	US 521 in Indian Land	01942-01-011942	current
SC 161	—	—	SC 16 in Eau Claire	US 176 / SC 19 in Union	01923-01-011923	01928-01-011928	First form
SC 161	28.910	46.526	US 21 / Cel-River Road in Rock Hill	NC 161 at the North Carolina state line northeast of Clover	01929-01-01c. 1929	current	Second form
SC 162	13.540	21.791	SC 174 in Adams Run	US 17 in Rantowles	01942-01-011942	current
SC 163	—	—	SC 16 in York	North Carolina state line in Lake Wylie	01926-01-01c. 1926	01938-01-011938
SC 164	2.500	4.023	SC 174 / Willtown Road near Hollywood	SC 162 in Hollywood	01942-01-011942	current
SC 165	28.393	45.694	Dead end on Yonges Island in Meggett	US 17 Alt. / US 17 Alt. Truck / Old Light Road in Summerville	01940-01-011940	current
SC 166	—	—	US 21 near Yemassee	US 17 near Hendersonville	01942-01-011942	01947-01-011947
SC 167	—	—	SC 11 northwest of Gaffney	North Carolina state line near Gaffney	01942-01-011942	01947-01-011947
SC 169	—	—	SC 170 north of Bluffton	Near Chelsea	01940-01-011940	01946-01-011946
SC 170	49.010	78.874	SR 25 at the Georgia state line southwest of Limehouse	U.S. Route 21 Bus. / Polk Street in Beaufort	01931-01-011931	current
SC 171	—	—	SC 261 in Greeleyville	US 521 in Bryans Crossroads	01930-01-011930	01949-01-011949	First form
SC 171	12.560	20.213	Arctic Avenue in Folly Beach	SC 7 in Charleston	01956-01-011956	current	Second form
SC 171Y	—	—	SC 171 in Greeleyville	Holliman Road near Greeleyville	01940-01-01c. 1940	01942-01-011942
SC 172	—	—	US 17 / US 701 in Whitehall Terrace	Clements Ferry Road in Cainhoy	01937-01-011937	01940-01-011940	First form
SC 172	9.000	14.484	US 178 near North	SC 6 near St. Matthews	01940-01-011940	current	Second form
SC 173	—	—	SC 27 in Ridgeville	US 78 / SC 2 near Ridgeville	01936-01-011936	01940-01-011940	First form
SC 173	1.570	2.527	SC 27 / School Street in Ridgeville	US 78 / Myers–Mayo Road near Ridgeville	01940-01-011940	current	Second form
SC 174	25.730	41.408	Yacht Club Road / Dock Site Road in Edisto Beach	US 17 in Osborn	01936-01-011936	current	Signed to begin at Dock Site Road / Buoy Road in Edisto Beach
SC 175	—	—	US 301 in Sardinia Sumter–Williamsburg county line northwest of Kingstree	SC 54 northwest of Sardinia SC 38 southeast of Marion	01928-01-011928	01952-01-011952
SC 177	—	—	US 176 / US 221 in Spartanburg	NC 192 at the North Carolina state line near Fingerville	01933-01-011933	01935-01-011935	First form
SC 177	—	—	US 176 near Newberry	US 76 / SC 2 east of Ballentine	01936-01-011936	01951-01-011951	Second form
SC 177	7.820	12.585	SC 9 / Delta Plant Road in Wallace	NC 177 at the North Carolina state line near Wallace	01961-01-011961	current	Third form
SC 178	—	—	US 17 near Moncks Corner	Berkeley–Charleston county line near Honey Hill	01928-01-011928	01933-01-011933
SC 179	—	—	US 52 near Moncks Corner	McClellanville	01933-01-011933	01950-01-011950	First form
SC 179	0.670	1.078	US 17 / Graystone Boulevard in Little River	NC 179 at the North Carolina state line near Little River	01980-01-011980	current	Second form
SC 180	—	—	US 29 in Blacksburg	North Carolina state line near Blacksburg	01942-01-011942	01947-01-011947
SC 181	—	—	West Pine Grove Road in Fair Play	US 76 / SC 13 / SC 28 in Seneca	01923-01-011923	01942-01-011942	First form
SC 181	6.430	10.348	SR 181 at the Georgia state line southwest of Starr	SC 412 in Starr	01942-01-011942	current	Second form
SC 182	9.580	15.418	SC 59 / SC 243 in Fair Play	SC 24 in Oakway	01925-01-01c. 1925	current
SC 183	53.712	86.441	US 76 / US 123 in Westminster	US 123 in Greenville	01926-01-01c. 1926	current
SC 184	34.610	55.699	SR 368 at the Georgia state line southwest of Iva	SC 252 Lower Shady Grove Road northwest of Ware Shoals	01925-01-01c. 1925	current
SC 185	26.920	43.324	US 178 southwest of Hodges	SC 28 southeast of Homeland Park	01938-01-011938	current
SC 186	14.960	24.076	SC 8 northeast of Pickens	US 276 in Slater-Marietta	01939-01-011939	current
SC 187	30.334	48.818	SC 184 southwest of Iva	US 76 / SC 28 south of Pendleton	01940-01-011940	current
SC 188	—	—	SC 184 east of Antreville	US 178 / SC 20 near Honea Path	01940-01-011940	01947-01-011947	First form
SC 188	8.250	13.277	SC 28 / Bountyland Road northwest of Seneca	SC 183 northeast of Walhalla	01971-01-011971	current	Second form
SC 190	—	—	SC 39 near Chappells	Old Cherokee Road near Silverstreet	01941-01-01c. 1941	01947-01-011947
SC 191	21.930	35.293	SC 421 / Howlandville Road in Warrenville	SC 121 / Hill Top Drive in Johnston	01936-01-011936	current
SC 192	—	—	US 76 / SC 2 near Newberry	US 76 / SC 2 north of Newberry	01928-01-01c. 1928	01947-01-011947
SC 193	6.930	11.153	SC 23 / Mt. Alpha Road in Ward	SC 121 / Gabe Road near Saluda	01937-01-011937	current
SC 194	14.690	23.641	US 178 Conn. / US 378 in Saluda	SC 391 near Stoney Hill	01939-01-011939	current
SC 195	—	—	SC 43 near Saluda	SC 194 northeast of Saluda	01942-01-011942	01947-01-011947
SC 196	—	—	SC 19 in Trenton	SC 23 southwest of Johnston	01940-01-011940	01947-01-011947
SC 197	—	—	SC 19 north of Johnston	US 178 near Saluda	01940-01-011940	01947-01-011947
SC 198	2.660	4.281	I-85 / SC 5 in Blacksburg	NC 198 at the North Carolina state line north of Blacksburg	01940-01-011940	current
SC 199	—	—	SC 19 near Aiken	US 1 near Aiken	01940-01-011940	01947-01-011947
SC 200	42.780	68.848	US 321 / SC 34 in Winnsboro	NC 200 at the North Carolina state line near Lancaster	01938-01-011938	current
SC 201	12.550	20.197	SC 20 north of Abbeville	SC 284 / Level Land Road near Antreville	01939-01-011939	current
SC 202	4.520	7.274	US 76 in Little Mountain	US 176 southeast of Pomaria	01939-01-011939	current
SC 203	7.750	12.472	SC 20 / Trinity Street in Abbeville	SC 185 southeast of Arborville	01940-01-011940	current
SC 204	—	—	US 78 near Reevesville	SC 152 northwest of Rosinville	01940-01-011940	01947-01-011947
SC 205	—	—	SC 391 in Prosperity	Lexington–Richland county line northeast of Chapin	01940-01-011940	01947-01-011947
SC 206	—	—	SC 525 in North Charleston	Yeamans Hall Club in Hanahan	01940-01-011940	01947-01-011947
SC 207	9.168	14.754	US 601 / SC 9 in Pageland	NC 207 at the North Carolina state line near Pageland	01940-01-011940	current
SC 208	—	—	Orangeburg–Dorchester county line west of Reevesville	SC 204 west of Reevesville	01942-01-011942	01947-01-011947
SC 209	—	—	US 21 in Lobeco	Witsell Road / Porches Hill Road in Dale	01942-01-011942	01947-01-011947
SC 210	—	—	US 301 in Orangeburg	US 21 / SC 2 in Sandy Run	01936-01-011936	01950-01-011950	First form
SC 210	28.580	45.995	US 21 in Branchville	SC 6 in Vance	01964-01-011964	current	Second form
SC 211	—	—	SC 21 in Travelers Rest	North Carolina state line in Caesars Head State Park near Cleveland	01925-01-01c. 1925	01928-01-011928	First form
SC 211	—	—	North Carolina state line northwest of Fort Mill	US 521 in Indian Land	01928-01-011928	01942-01-011942	Second form
SC 211	27.380	44.064	SC 150 northeast of Pacolet	SC 49 in Sharon	01942-01-011942	current	Third form
SC 212	5.670	9.125	SC 64 northwest of Bells Crossroads	US 21 east of Williams	01937-01-011937	current
SC 213	21.380	34.408	US 176 / Parr Road near Peak	US 321 / US 321 Bus. / SC 34 southwest of Winnsboro Mills	01939-01-011939	current
SC 214	—	—	SC 280 in Port Royal	US 21 in Burton	01940-01-011940	01947-01-011947
SC 215	96.330	155.028	US 21 / US 321 in Columbia	SC 295 / SC 296 in Spartanburg	01928-01-011928	current
SC 216	—	—	US 21 northwest of Sheldon	US 21 in Sheldon	01939-01-011939	01947-01-011947	First form
SC 216	1.220	1.963	Battleground Road at Kings Mountain National Military Park near Blacksburg	NC 216 at the North Carolina state line northeast of Blacksburg	01960-01-011960	current	Second form
SC 217	15.390	24.768	SC 64 in Lodge	SC 61 northwest of Canadys	01936-01-011936	current
SC 218	—	—	US 21 / SC 5 northeast of Eau Claire	US 21 / SC 219 southwest of Winnsboro Mills	01939-01-011939	01950-01-011950
SC 219	9.030	14.532	US 76 / SC 34 in Newberry	US 176 northwest of Pomaria	01937-01-011937	current
SC 220	—	—	SC 605 near St. Matthews	SC 6 west of St. Matthews	01940-01-011940	01947-01-011947
SC 222	—	—	SC 22 southeast of Blair	SC 215 near Blair	01938-01-011938	01947-01-011947
SC 223	—	—	SC 22 near Mitford	Fairfield–Chester county line near Mitford	01939-01-011939	01940-01-011940	First form
SC 223	6.740	10.847	SC 9 / SC 901 north of Richburg	US 21 / W.D. Hattie Lane in Landsford	01940-01-011940	current	Second form
SC 224	—	—	SC 269 near Rion	SC 34 west of Longtown	01940-01-011940	01947-01-011947
SC 225	—	—	SC 39 near Ware Shoals	SC 39 in Cross Hill	01940-01-011940	01947-01-011947	First form
SC 225	5.900	9.495	US 25 / US 178 near Greenwood	SC 72 Bus. / Calhoun Road west of Greenwood	01973-01-011973	current	Second form
SC 226	—	—	US 21 in White Oak	Near White Oak	01940-01-011940	01947-01-011947
SC 227	—	—	US 21 in Adger	SC 704 northwest of Blackstock	01940-01-011940	01947-01-011947
SC 228	—	—	US 276 / SC 2 in Barksdale	US 221 near Ora	01940-01-011940	01947-01-011947
SC 229	—	—	SC 227 near Blackstock	SC 901 southwest of Mitford	01942-01-011942	01947-01-011947
SC 230	20.730	33.362	US 25 / SC 121 / SC 125 in North Augusta	SC 25 in West Store Crossroads	01939-01-011939	current	Signage and SCDOT reference indicates the southern terminus is at US 25 / SC 121 (Knox Avenue), also in North Augusta.
SC 231	—	—	SC 430 northwest of Johnston	US 1 near Ridge Spring	01940-01-011940	01947-01-011947
SC 232	—	—	SC 397 southwest of Ridge Spring	SC 23 / SC 39 in Ridge Spring	01940-01-011940	01947-01-011947
SC 233	—	—	SC 231 near Ward	SC 193 near Ward	01940-01-011940	01947-01-011947
SC 234	—	—	SC 23 in Ward	SC 434 near Batesburg	01940-01-011940	01947-01-011947
SC 235	—	—	SC 6 / SC 210 near Wolfton	SC 267 in Fort Motte	01940-01-011940	01947-01-011947
SC 236	—	—	SC 117 near St. Matthews	SC 235 near St. Matthews	01942-01-011942	01947-01-011947
SC 237	—	—	SC 404 near Johnston	SC 19 in Johnston	01942-01-011942	01947-01-011947
SC 238	—	—	Aiken–Edgefield county line southeast of Ridge Spring	SC 23 / SC 39 in Ridge Spring	01942-01-011942	01947-01-011947
SC 239	—	—	SC 235 near Hammond Crossroads	US 21 / SC 2 southwest of Hammond Crossroads	01942-01-011942	01947-01-011947
SC 240	—	—	US 15 near Rosinville	US 178 / SC 2 southeast of Rosinville	01944-01-01c. 1944	01947-01-011947
SC 241	—	—	Edgefield–Greenwood county line south of Pittsburg	SC 246 south east of Ninety Six	01942-01-011942	01947-01-011947
SC 242	—	—	SC 243 near Fair Play	SC 24 / SC 181 near Oakway	01940-01-011940	01947-01-011947
SC 243	8.380	13.486	SC 59 / SC 182 in Fair Play	I-85 / SC 24 southeast of Townville	01940-01-011940	current
SC 244	—	—	SC 24 in Townville	US 76 / SC 13 / SC 28 in Seneca	01940-01-011940	01947-01-011947
SC 245	5.060	8.143	US 178 in Kneece	SC 391 / Lodestar Road north of Batesburg–Leesville	01929-01-011929	current
SC 246	28.700	46.188	US 178 in Friendship	US 178 in Hodges	01929-01-011929	current
SC 247	10.700	17.220	SC 20 / Breazeale Street in Belton	US 25 in Ware Place	01929-01-011929	current
SC 248	—	—	US 29 in Anderson	SC 20 in Williamston	01929-01-011929	01935-01-011935	First form
SC 248	6.170	9.930	US 178 in Epworth	SC 34 / SC 246 in Ninety Six	01940-01-011940	current	Second form
SC 249	—	—	SC 80 near Anderson	US 76 / US 178 / SC 28	01940-01-011940	01947-01-011947
SC 250	—	—	US 25 in Donaldson	US 276 near Marietta	01937-01-01c. 1937	01968-01-01c. 1968
SC 251	—	—	US 25 near Cleveland	Mountain Page Road at the North Carolina state line northeast of Cleveland	01937-01-01c. 1937	01947-01-011947
SC 252	35.711	57.471	US 76 / US 178 southeast of Anderson	US 76 west of Laurens	01938-01-011938	current
SC 253	19.656	31.633	SC 124 in Parker	SC 414 / North Tigerville Road in Tigerville	01939-01-011939	current
SC 254	8.230	13.245	SC 72 Bus. in Greenwood	US 25 northwest of Cokesbury	01940-01-011940	current
SC 255	—	—	US 29 / SC 250 in Gantt	US 25 in Greenville	01939-01-011939	01949-01-01c. 1949
SC 256	—	—	US 178 / SC 20 in Donalds	SC 252 northwest of Ware Shoals	01940-01-011940	01947-01-011947
SC 257	—	—	SC 201 southwest of Due West	SC 284 nea Honea Path	01942-01-011942	01956-01-011956	Two instances: 1942 to 1947 and 1950 to 1956
SC 258	—	—	US 521 in Alcolu	Brogdon Road north of Alcolu	01940-01-011940	01947-01-011947
SC 259	—	—	US 25 northwest of Bath	US 1 / US 78 west of Aiken	01942-01-011942	01947-01-011947
SC 260	12.520	20.149	Santee Dam in Eagle Point	SC 261 in Manning	01939-01-011939	current
SC 261	116.960	188.229	US 701 in Yauhannah	US 521 south of Camden	01923-01-011923	current
SC 262	14.750	23.738	US 76 / US 378 / Veterans Road in Columbia	US 601 / Westvaco Road in Leesburg	01938-01-011938	current
SC 263	5.250	8.449	SC 764 in Eastover	US 76 / US 378 near Eastover	01937-01-011937	current
SC 264	—	—	SC 26 near Fort Motte	Lone Star Road in Lone Star	01939-01-011939	01940-01-011940	First form
SC 264	—	—	US 321 in Bowling Green	SC 557 west of Lake Wylie	01940-01-011940	01947-01-011947	Second form
SC 265	24.690	39.735	US 601 near Kershaw	SC 9 southeast of Ruby	01926-01-011926	current
SC 266	—	—	SC 260 west of Bloomville	Great Savannah Church Road southeast of Jordan	01939-01-011939	01947-01-011947
SC 267	23.200	37.337	US 15 near Santee	US 601 / Adams Road near Wiles Crossroads	01940-01-011940	current
SC 268	5.630	9.061	SC 265 / Steen Road southwest of Ruby	SC 9 / SC 109 in Mount Croghan	01940-01-011940	current
SC 269	11.950	19.232	SC 215 west of Blythewood	US 321 south of Winnsboro Mills	01942-01-011942	current
SC 270	—	—	US 1 in Blaney	SC 213 near Blaney	01942-01-011942	01947-01-011947
SC 271	—	—	US 76 northwest of Westminster	SC 288 in Salem	01942-01-011942	01971-01-011971
SC 272	—	—	SC 185 west of Due West	SC 256 in Donalds	01942-01-011942	01947-01-011947
SC 273	—	—	SC 96 in Tradesville	SC 207 south of Wolf Pond Cross Roads	01942-01-011942	01947-01-011947
SC 274	17.537	28.223	NC 274 at the North Carolina state line northwest of Lake Wylie	SC 322 in Rock Hill	01938-01-011938	current
SC 275	—	—	SC 905 in Red Bluff Crossroads	SC 9 in Loris	01942-01-011942	01947-01-011947
SC 277	—	—	SC 215 southwest of Blythewood	SC 218 southwest of Blythewood	01942-01-011942	01947-01-011947	First form
SC 277	8.140	13.100	US 76 in Columbia	I-77 in Dentsville	01976-01-011976	current	Second form
SC 278	—	—	Southeast of Chappells	SC 19 near Chappells	01942-01-011942	01947-01-011947
SC 279	—	—	SC 154 near St. Charles	SC 34 southeast of Antioch	01942-01-011942	01947-01-011947
SC 280	—	—	SC 281 / Parris Island access road in Port Royal	US 21 in Burton	01929-01-01c. 1929	02012-01-012012
SC 281	—	—	SC 28 near Ellenton	SC 37 in Barnwell	01925-01-01c. 1925	01926-01-011926	First form
SC 281	3.190	5.134	US 21 in Port Royal	US 21 Bus. in Beaufort	01928-01-01c. 1928	current	Second form
SC 282	—	—	SC 28 northwest of Millett	SC 28 northeast of Millett	01939-01-011939	01947-01-011947
SC 283	17.840	28.711	US 221 / SC 28 / Collier Street in Plum Branch	US 25 northwest of Edgefield	01939-01-011939	current
SC 284	—	—	SC 81 / Tom Young Bridge Road southeast of Lowndesville	SC 28 / SC 184 east of Antreville	01928-01-011928	01932-01-011932	First form
SC 284	19.590	31.527	SC 81 / Tom Young Bridge Road southeast of Lowndesville	SC 28 / SC 184 east of Antreville	01940-01-011940	current	Second form
SC 285	—	—	US 21 / SC 281 in Beaufort	Hunting Island	01939-01-011939	01954-01-011954
SC 286	—	—	SC 367 southwest of Early Branch	SC 32 northeast of Sheldon	01940-01-011940	01947-01-011947
SC 287	—	—	SC 82 in Mount Carmel	SC 432 near Troy	01940-01-011940	01947-01-011947
SC 288	15.260	24.559	US 178 / SC 11 near Sunset	US 276 in Slater-Marietta	01940-01-011940	current
SC 289	—	—	US 76 / SC 28 in Calhoun	Clemson College in Calhoun	01940-01-011940	01947-01-011947
SC 290	30.582	49.217	US 25 east of Slater-Marietta	US 221 in Moore	01937-01-01c. 1937	current
SC 291	11.400	18.347	US 25 / White Horse Road Extension in Gantt	SC 253 east of Sans Souci	01939-01-011939	current	Signed to end at US 276 / SC 253 in Sans Souci
SC 292	13.640	21.951	SC 290 in Duncan	SC 9 northwest of Boiling Springs	01939-01-011939	current
SC 293	—	—	US 29 northeast of Blacksburg	Battleground Road northeast of Blacksburg	01940-01-011940	01947-01-011947