Mitochondrial thiamine pyrophosphate carrier

SLC25A19
Identifiers
Aliases	SLC25A19, DNC, MCPHA, MUP1, THMD3, THMD4, TPC, solute carrier family 25 member 19
External IDs	OMIM: 606521; MGI: 1914533; HomoloGene: 5982; GeneCards: SLC25A19; OMA:SLC25A19 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	75,289,510 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	115,519,121 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; stromal cell of endometrium; ; right adrenal cortex; ; left adrenal cortex; ; appendix; ; granulocyte; ; mucosa of transverse colon; ; apex of heart; ; lymph node;
	Top expressed in
	neural layer of retina; ; right kidney; ; brown adipose tissue; ; saccule; ; temporal muscle; ; muscle of thigh; ; proximal tubule; ; superior frontal gyrus; ; primary visual cortex; ; sternocleidomastoid muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	deoxynucleotide transmembrane transporter activity; thiamine pyrophosphate transmembrane transporter activity; thiamine transmembrane transporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; nucleus; mitochondrion; membrane; mitochondrial inner membrane; integral component of mitochondrial inner membrane;
Biological process	deoxynucleotide transport; transmembrane transport; thiamine-containing compound metabolic process; mitochondrial transport; thiamine pyrophosphate transmembrane transport; thiamine transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	60386
	67283
	ENSG00000125454
	ENSMUSG00000020744
	Q9HC21
	Q9DAM5
	NM_001126121; NM_001126122; NM_021734
	NM_001252384; NM_001252394; NM_001252395; NM_001252396; NM_026071
	NP_001119593; NP_001119594; NP_068380
	NP_001239313; NP_001239323; NP_001239324; NP_001239325; NP_080347
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial thiamine pyrophosphate carrier is a protein that in humans is encoded by the SLC25A19 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125454 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020744 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176. S2CID 44985945.
^ Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. Bibcode:2001PNAS...98.2284D. doi:10.1073/pnas.031430998. PMC 30130. PMID 11226231.
^ "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".

External links

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125454 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020744 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11474176-5] Iacobazzi V, Ventura M, Fiermonte G, Prezioso G, Rocchi M, Palmieri F (Jul 2001). "Genomic organization and mapping of the gene (SLC25A19) encoding the human mitochondrial deoxynucleotide carrier (DNC)". Cytogenet Cell Genet. 93 (1–2): 40–2. doi:10.1159/000056945. PMID 11474176. S2CID 44985945.

[pmid11226231-6] Dolce V, Fiermonte G, Runswick MJ, Palmieri F, Walker JE (Mar 2001). "The human mitochondrial deoxynucleotide carrier and its role in the toxicity of nucleoside antivirals". Proc Natl Acad Sci U S A. 98 (5): 2284–8. Bibcode:2001PNAS...98.2284D. doi:10.1073/pnas.031430998. PMC 30130. PMID 11226231.

[entrez-7] "Entrez Gene: SLC25A19 solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19".

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Mitochondrial thiamine pyrophosphate carrier

See also

References

Further reading

External links