Mammalian protein found in Homo sapiens
Choline transporter-like protein 1 is a protein that in humans is encoded by the SLC44A1 gene .[ 5] [ 6] [ 7]
Papillary glioneuronal tumors characteristically exhibit a gene fusion between SLC44A1 and PRKCA [ 8] [ 9] [ 10] [ 11]
^ a b c GRCh38: Ensembl release 89: ENSG00000070214 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028412 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H (November 2001). "Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells" . Journal of Immunology . 167 (10): 5795–5804. doi :10.4049/jimmunol.167.10.5795 PMID 11698453 . ^ O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (February 2000). "An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins" . Proceedings of the National Academy of Sciences of the United States of America . 97 (4): 1835–40. Bibcode :2000PNAS...97.1835O . doi :10.1073/pnas.030339697 PMC 26522 PMID 10677542 . ^ "Entrez Gene: SLC44A1 solute carrier family 44, member 1" .^ Bridge JA, Liu XQ, Sumegi J, Nelson M, Reyes C, Bruch LA, Rosenblum M, Puccioni MJ, Bowdiono BS, McComb RD (2013). "Identification of a Novel, Recurrent SLC44A1-PRKCA Fusion in Papillary Glioneuronal Tumor" . Brain Pathology . 23 (2): 121–128. doi :10.1111/j.1750-3639.2012.00612.x PMC 8029478 PMID 22725730 . ^ Pages M, Lacroix L, Tauziede-Espariat A, Castel D, Daudigeos-Dubus E, Ridola V, et al. (2015). "Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion" . Acta Neuropathologica Communications . 3 : 85. doi :10.1186/s40478-015-0264-5 PMC 4681033 PMID 26671581 . 85. ^ Nagaishi M, Nobusawa S, Matsumura N, Kono F, Ishiuchi S, Abe T, Ebato M, Wang Y, Hyodo A, Yokoo H, Nakazato Y (2016). "SLC44A1 – PRKCA fusion in papillary and rosette-forming glioneuronal tumors". Journal of Clinical Neuroscience . 23 : 73–75. doi :10.1016/j.jocn.2015.04.021 . PMID 26260115 . S2CID 140207877 . ^ Taylor A, Grapentine S, Ichhpuniani J, Bakovic M (2021). "Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters" . J Biol Chem . 296 : 100604. doi :10.1016/j.jbc.2021.100604 . PMC 8081925 PMID 33789160 . {{cite journal }}: CS1 maint: multiple names: authors list (link ) Yuan Z, Tie A, Tarnopolsky M, Bakovic M (June 2006). "Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1" (PDF) . Physiological Genomics . 26 (1): 76–90. doi :10.1152/physiolgenomics.00107.2005 . PMID 16609143 . S2CID 8181779 . Archived from the original (PDF) on 2019-03-04. Fullerton MD, Wagner L, Yuan Z, Bakovic M (April 2006). "Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages" (PDF) . American Journal of Physiology. Cell Physiology . 290 (4): C1230–C1238. doi :10.1152/ajpcell.00255.2005 . PMID 16319125 . S2CID 5096497 . Archived from the original (PDF) on 2019-02-22. Li D, Wang F, Lai M, Chen Y, Zhang JF (February 2005). "A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C" . The Journal of Neuroscience . 25 (8): 1914–23. doi :10.1523/JNEUROSCI.4790-04.2005 PMC 6726054 PMID 15728831 . Traiffort E, Ruat M, O'Regan S, Meunier FM (March 2005). "Molecular characterization of the family of choline transporter-like proteins and their splice variants" . Journal of Neurochemistry . 92 (5): 1116–25. doi :10.1111/j.1471-4159.2004.02962.x PMID 15715662 . S2CID 30921826 . Lecomte MJ, De Gois S, Guerci A, Ravassard P, Faucon Biguet N, Mallet J, Berrard S (February 2005). "Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia". Molecular and Cellular Neurosciences . 28 (2): 303–13. doi :10.1016/j.mcn.2004.09.014 . PMID 15691711 . S2CID 20828310 . Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P (December 2003). "Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3" . Proceedings of the National Academy of Sciences of the United States of America . 100 (26): 16006–11. Bibcode :2003PNAS..10016006F . doi :10.1073/pnas.2136600100 PMC 307683 PMID 14663150 . Takekawa M, Maeda T, Saito H (August 1998). "Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways" . The EMBO Journal . 17 (16): 4744–52. doi :10.1093/emboj/17.16.4744 . PMC 1170803 PMID 9707433 .
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